Influenza Virus M2 Protein Ion Channel Activity Helps To Maintain Pandemic 2009 H1N1 Virus Hemagglutinin Fusion Competence during Transport to the Cell Surface

Aminoadamantanes with Persistent in Vitro Efficacy against H1N1 (2009) Influenza A

(2014) Antonios Kolocouris et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structural Stability of Influenza A(H1N1)pdm09 Virus Hemagglutinins

(2014) H. Yang et al.   JOURNAL OF VIROLOGY

The Matrix Gene Segment Destabilizes the Acid and Thermal Stability of the Hemagglutinin of Pandemic Live Attenuated Influenza Virus Vaccines

(2014) C. D. O'Donnell et al.   JOURNAL OF VIROLOGY

A Single Amino Acid in the Stalk Region of the H1N1pdm Influenza Virus HA Protein Affects Viral Fusion, Stability and Infectivity

(2014) Christopher R. Cotter et al.   PLoS Pathogens

Egg- or cell culture-derived hemagglutinin mutations impair virus stability and antigen content of inactivated influenza vaccines

(2013) Sabine Nakowitsch et al.   Biotechnology Journal

Influenza HA Subtypes Demonstrate Divergent Phenotypes for Cleavage Activation and pH of Fusion: Implications for Host Range and Adaptation

(2013) Summer E. Galloway et al.   PLoS Pathogens

Pandemic influenza vaccine: characterization of A/California/07/2009 (H1N1) recombinant hemagglutinin protein and insights into H1N1 antigen stability

(2012) Elena Feshchenko et al.   BMC BIOTECHNOLOGY

Neutralizing and protective epitopes of the 2009 pandemic influenza H1N1 hemagglutinin

(2012) Falko Schmeisser et al.   Influenza and Other Respiratory Viruses

Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

(2012) Masaki Imai et al.   NATURE

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets

(2012) S. Herfst et al.   SCIENCE

Structural Characterization of an Early Fusion Intermediate of Influenza Virus Hemagglutinin

(2011) R. Xu et al.   JOURNAL OF VIROLOGY

Selection with a Peptide Fusion Inhibitor Corresponding to the First Heptad Repeat of HIV-1 gp41 Identifies Two Genetic Pathways Conferring Cross-Resistance to Peptide Fusion Inhibitors Corresponding to the First and Second Heptad Repeats (HR1 and HR2) of gp41

(2011) W. Wang et al.   JOURNAL OF VIROLOGY

Enhanced Growth of Influenza Vaccine Seed Viruses in Vero Cells Mediated by Broadening the Optimal pH Range for Virus Membrane Fusion

(2011) S. Murakami et al.   JOURNAL OF VIROLOGY

Single HA2 Mutation Increases the Infectivity and Immunogenicity of a Live Attenuated H5N1 Intranasal Influenza Vaccine Candidate Lacking NS1

(2011) Brigitte M. Krenn et al.   PLoS One

Antigenic stability of H1N1 pandemic vaccines correlates with vaccine strain

(2011) Aaron Farnsworth et al.   VACCINE

Mutations affecting the stability of the haemagglutinin molecule impair the immunogenicity of live attenuated H3N2 intranasal influenza vaccine candidates lacking NS1

(2011) Sabine Nakowitsch et al.   VACCINE

Influenza virus assembly and budding

(2011) Jeremy S. Rossman et al.   VIROLOGY

Cross-Neutralizing Antibodies to Pandemic 2009 H1N1 and Recent Seasonal H1N1 Influenza A Strains Influenced by a Mutation in Hemagglutinin Subunit 2

(2011) Wei Wang et al.   PLoS Pathogens

Resistance characteristics of influenza to amino-adamantyls

(2010) Peleg Astrahan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Influenza Virus M2 Protein Mediates ESCRT-Independent Membrane Scission

(2010) Jeremy S. Rossman et al.   CELL

Novel Inhibitors of Influenza Virus Fusion: Structure-Activity Relationship and Interaction with the Viral Hemagglutinin

(2010) E. Vanderlinden et al.   JOURNAL OF VIROLOGY

Cleavage of Influenza Virus Hemagglutinin by Airway Proteases TMPRSS2 and HAT Differs in Subcellular Localization and Susceptibility to Protease Inhibitors

(2010) E. Bottcher-Friebertshauser et al.   JOURNAL OF VIROLOGY

Influenza Virus M2 Ion Channel Protein Is Necessary for Filamentous Virion Formation

(2010) J. S. Rossman et al.   JOURNAL OF VIROLOGY

Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus

(2010) R. Acharya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A mutation in the receptor binding site enhances infectivity of 2009 H1N1 influenza hemagglutinin pseudotypes without changing antigenicity

(2010) Wei Wang et al.   VIROLOGY

Functional Studies and Modeling of Pore-Lining Residue Mutants of the Influenza A Virus M2 Ion Channel

(2009) Victoria Balannik et al.   BIOCHEMISTRY

Amino Acid Residues in the Fusion Peptide Pocket Regulate the pH of Activation of the H5N1 Influenza Virus Hemagglutinin Protein

(2009) M. L. Reed et al.   JOURNAL OF VIROLOGY

The pH of Activation of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Pathogenicity and Transmissibility in Ducks

(2009) M. L. Reed et al.   JOURNAL OF VIROLOGY

Influenza virus morphogenesis and budding

(2009) Debi P. Nayak et al.   VIRUS RESEARCH

Adamantane resistance in influenza A(H1) viruses increased in 2007 in South East Asia but decreased in Australia and some other countries

(2008) I BARR et al.   ANTIVIRAL RESEARCH

Increased Incidence of Adamantane‐Resistant Influenza A(H1N1) and A(H3N2) Viruses During the 2006–2007 Influenza Season in Japan

(2008) Reiko Saito et al.   JOURNAL OF INFECTIOUS DISEASES

Establishment of retroviral pseudotypes with influenza hemagglutinins from H1, H3, and H5 subtypes for sensitive and specific detection of neutralizing antibodies

(2008) Wei Wang et al.   JOURNAL OF VIROLOGICAL METHODS

The Influenza Virus M2 Protein Cytoplasmic Tail Interacts with the M1 Protein and Influences Virus Assembly at the Site of Virus Budding

(2008) B. J. Chen et al.   JOURNAL OF VIROLOGY

Structure and mechanism of the M2 proton channel of influenza A virus

(2008) Jason R. Schnell et al.   NATURE

Structural basis for the function and inhibition of an influenza virus proton channel

(2008) Amanda L. Stouffer et al.   NATURE

Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel

(2008) X. Jing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Interplay of Functional Tuning, Drug Resistance, and Thermodynamic Stability in the Evolution of the M2 Proton Channel from the Influenza A Virus

(2008) Amanda L. Stouffer et al.   STRUCTURE