Selection with a Peptide Fusion Inhibitor Corresponding to the First Heptad Repeat of HIV-1 gp41 Identifies Two Genetic Pathways Conferring Cross-Resistance to Peptide Fusion Inhibitors Corresponding to the First and Second Heptad Repeats (HR1 and HR2) of gp41

Contribution of Intrinsic Reactivity of the HIV-1 Envelope Glycoproteins to CD4-Independent Infection and Global Inhibitor Sensitivity

(2011) Hillel Haim et al.   PLoS Pathogens

Short Communication: High Polymorphism Rates in the HR1 and HR2 gp41 and Presence of Primary Resistance-Related Mutations in HIV Type 1 Circulating in Brazil: Possible Impact on Enfuvirtide Efficacy

(2010) Carla Teixeira et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Characterization of HIV-1 resistance to a fusion inhibitor, N36, derived from the gp41 amino-terminal heptad repeat

(2010) Kazuki Izumi et al.   ANTIVIRAL RESEARCH

A V3 Loop-Dependent gp120 Element Disrupted by CD4 Binding Stabilizes the Human Immunodeficiency Virus Envelope Glycoprotein Trimer

(2010) S.-H. Xiang et al.   JOURNAL OF VIROLOGY

Analysis of HIV Type 1 gp41 and Enfuvirtide Susceptibility among Men in the United States Who Were HIV Infected Prior to Availability of HIV Entry Inhibitors

(2009) Sarah E. Hudelson et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

HR-2 Mutations in Human Immunodeficiency Virus Type 1 gp41 Restore Fusion Kinetics Delayed by HR-1 Mutations That Cause Clinical Resistance to Enfuvirtide

(2009) N. Ray et al.   JOURNAL OF VIROLOGY

Early Steps of HIV-1 Fusion Define the Sensitivity to Inhibitory Peptides That Block 6-Helix Bundle Formation

(2009) Kosuke Miyauchi et al.   PLoS Pathogens

Asymmetric Deactivation of HIV-1 gp41 following Fusion Inhibitor Binding

(2009) Kristen M. Kahle et al.   PLoS Pathogens

Impact of the Enfuvirtide Resistance Mutation N43D and the Associated Baseline Polymorphism E137K on Peptide Sensitivity and Six-Helix Bundle Structure†‡

(2008) Xuefang Bai et al.   BIOCHEMISTRY

Design of an engineered N-terminal HIV-1 gp41 trimer with enhanced stability and potency

(2008) John J. Dwyer et al.   PROTEIN SCIENCE

Enhancing Exposure of HIV-1 Neutralization Epitopes through Mutations in gp41

(2007) Catherine A Blish et al.   PLOS MEDICINE