Probing the Functions of the Paramyxovirus Glycoproteins F and HN with a Panel of Synthetic Antibodies

Fusion Activation through Attachment Protein Stalk Domains Indicates a Conserved Core Mechanism of Paramyxovirus Entry into Cells

(2014) S. Bose et al.   JOURNAL OF VIROLOGY

Mutations in the Parainfluenza Virus 5 Fusion Protein Reveal Domains Important for Fusion Triggering and Metastability

(2013) S. Bose et al.   JOURNAL OF VIROLOGY

A Stabilized Headless Measles Virus Attachment Protein Stalk Efficiently Triggers Membrane Fusion

(2013) M. A. Brindley et al.   JOURNAL OF VIROLOGY

Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

(2013) J. S. McLellan et al.   SCIENCE

Unraveling a Three-Step Spatiotemporal Mechanism of Triggering of Receptor-Induced Nipah Virus Fusion and Cell Entry

(2013) Qian Liu et al.   PLoS Pathogens

Structure of the Parainfluenza Virus 5 (PIV5) Hemagglutinin-Neuraminidase (HN) Ectodomain

(2013) Brett D. Welch et al.   PLoS Pathogens

Two Synthetic Antibodies that Recognize and Neutralize Distinct Proteolytic Forms of the Ebola Virus Envelope Glycoprotein

(2012) Jayne F. Koellhoffer et al.   CHEMBIOCHEM

Structural Rearrangements of the Central Region of the Morbillivirus Attachment Protein Stalk Domain Trigger F Protein Refolding for Membrane Fusion

(2012) Nadine Ader et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Fusion Triggering

(2012) Chanakha K. Navaratnarajah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Generating conformation-specific synthetic antibodies to trap proteins in selected functional states

(2012) Marcin Paduch et al.   METHODS

Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site

(2012) Xiaolin Wen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

T Cell Receptor-Like Recognition of Tumor In Vivo by Synthetic Antibody Fragment

(2012) Keith R. Miller et al.   PLoS One

Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion protein

(2012) B. D. Welch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Triggering the measles virus membrane fusion machinery

(2012) M. A. Brindley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fusion activation by a headless parainfluenza virus 5 hemagglutinin-neuraminidase stalk suggests a modular mechanism for triggering

(2012) S. Bose et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the Ulster Strain Newcastle Disease Virus Hemagglutinin-Neuraminidase Reveals Auto-Inhibitory Interactions Associated with Low Virulence

(2012) Ping Yuan et al.   PLoS Pathogens

Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes

(2011) J. S. McLellan et al.   JOURNAL OF VIROLOGY

Structure and Mutagenesis of the Parainfluenza Virus 5 Hemagglutinin-Neuraminidase Stalk Domain Reveals a Four-Helix Bundle and the Role of the Stalk in Fusion Promotion

(2011) S. Bose et al.   JOURNAL OF VIROLOGY

The heads of the measles virus attachment protein move to transmit the fusion-triggering signal

(2011) Chanakha K Navaratnarajah et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers

(2011) K. A. Swanson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Capture and imaging of a prehairpin fusion intermediate of the paramyxovirus PIV5

(2011) Y. H. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a four-helix bundle stalk

(2011) P. Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Using Sculptor and Situs for simultaneous assembly of atomic components into low-resolution shapes

(2010) Stefan Birmanns et al.   JOURNAL OF STRUCTURAL BIOLOGY

Dimeric Architecture of the Hendra Virus Attachment Glycoprotein: Evidence for a Conserved Mode of Assembly

(2010) T. A. Bowden et al.   JOURNAL OF VIROLOGY

Blue Native PAGE and Biomolecular Complementation Reveal a Tetrameric or Higher-Order Oligomer Organization of the Physiological Measles Virus Attachment Protein H

(2010) M. A. Brindley et al.   JOURNAL OF VIROLOGY

Structure of the Newcastle disease virus F protein in the post-fusion conformation

(2010) Kurt Swanson et al.   VIROLOGY

The Importance of Being Tyrosine: Lessons in Molecular Recognition from Minimalist Synthetic Binding Proteins

(2009) Shohei Koide et al.   ACS Chemical Biology

Probing the Spatial Organization of Measles Virus Fusion Complexes

(2009) T. Paal et al.   JOURNAL OF VIROLOGY

Structure of the measles virus hemagglutinin bound to the CD46 receptor

(2009) César Santiago et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Stable Prefusion Intermediate of the Alphavirus Fusion Protein Reveals Critical Features of Class II Membrane Fusion

(2008) Claudia Sánchez-San Martín et al.   Cell Host & Microbe

A Novel Receptor-induced Activation Site in the Nipah Virus Attachment Glycoprotein (G) Involved in Triggering the Fusion Glycoprotein (F)

(2008) Hector C. Aguilar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Interaction between Paramyxovirus Fusion and Attachment Proteins

(2008) Jin K. Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Residues in the Stalk Domain of the Hendra Virus G Glycoprotein Modulate Conformational Changes Associated with Receptor Binding

(2008) K. A. Bishop et al.   JOURNAL OF VIROLOGY

Crystal Structure and Carbohydrate Analysis of Nipah Virus Attachment Glycoprotein: a Template for Antiviral and Vaccine Design

(2008) T. A. Bowden et al.   JOURNAL OF VIROLOGY

Viral membrane fusion

(2008) Stephen C Harrison   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2

(2008) Thomas A Bowden et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Host cell recognition by the henipaviruses: Crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3

(2008) K. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Paramyxoviruses: different receptors – different mechanisms of fusion

(2008) Ronald M. Iorio et al.   TRENDS IN MICROBIOLOGY

Domain architecture and oligomerization properties of the paramyxovirus PIV 5 hemagglutinin-neuraminidase (HN) protein

(2008) Ping Yuan et al.   VIROLOGY