Fusion Activation through Attachment Protein Stalk Domains Indicates a Conserved Core Mechanism of Paramyxovirus Entry into Cells

A Mutation in the Stalk of the Newcastle Disease Virus Hemagglutinin-Neuraminidase (HN) Protein Prevents Triggering of the F Protein despite Allowing Efficient HN-F Complex Formation

(2013) A. M. Mirza et al.   JOURNAL OF VIROLOGY

Mutations in the Parainfluenza Virus 5 Fusion Protein Reveal Domains Important for Fusion Triggering and Metastability

(2013) S. Bose et al.   JOURNAL OF VIROLOGY

Measles Virus Fusion Machinery Activated by Sialic Acid Binding Globular Domain

(2013) A. Talekar et al.   JOURNAL OF VIROLOGY

A Stabilized Headless Measles Virus Attachment Protein Stalk Efficiently Triggers Membrane Fusion

(2013) M. A. Brindley et al.   JOURNAL OF VIROLOGY

Individual N-Glycans Added at Intervals along the Stalk of the Nipah Virus G Protein Prevent Fusion but Do Not Block the Interaction with the Homologous F Protein

(2013) Q. Zhu et al.   JOURNAL OF VIROLOGY

The Receptor Attachment Function of Measles Virus Hemagglutinin Can Be Replaced with an Autonomous Protein That Binds Her2/neu While Maintaining Its Fusion-Helper Function

(2013) A. Rasbach et al.   JOURNAL OF VIROLOGY

Hydrophobic and Charged Residues in the Central Segment of the Measles Virus Hemagglutinin Stalk Mediate Transmission of the Fusion-Triggering Signal

(2013) S. Apte-Sengupta et al.   JOURNAL OF VIROLOGY

Cross-neutralization of four paramyxoviruses by a human monoclonal antibody

(2013) Davide Corti et al.   NATURE

Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

(2013) J. S. McLellan et al.   SCIENCE

Unraveling a Three-Step Spatiotemporal Mechanism of Triggering of Receptor-Induced Nipah Virus Fusion and Cell Entry

(2013) Qian Liu et al.   PLoS Pathogens

Structure of the Parainfluenza Virus 5 (PIV5) Hemagglutinin-Neuraminidase (HN) Ectodomain

(2013) Brett D. Welch et al.   PLoS Pathogens

Structural Rearrangements of the Central Region of the Morbillivirus Attachment Protein Stalk Domain Trigger F Protein Refolding for Membrane Fusion

(2012) Nadine Ader et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Fusion Triggering

(2012) Chanakha K. Navaratnarajah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Second Receptor Binding Site of the Globular Head of the Newcastle Disease Virus Hemagglutinin-Neuraminidase Activates the Stalk of Multiple Paramyxovirus Receptor Binding Proteins To Trigger Fusion

(2012) M. Porotto et al.   JOURNAL OF VIROLOGY

Cysteines in the Stalk of the Nipah Virus G Glycoprotein Are Located in a Distinct Subdomain Critical for Fusion Activation

(2012) D. Maar et al.   JOURNAL OF VIROLOGY

Triggering the measles virus membrane fusion machinery

(2012) M. A. Brindley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fusion activation by a headless parainfluenza virus 5 hemagglutinin-neuraminidase stalk suggests a modular mechanism for triggering

(2012) S. Bose et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Paramyxovirus Fusion and Entry: Multiple Paths to a Common End

(2012) Andres Chang et al.   Viruses-Basel

Bats host major mammalian paramyxoviruses

(2012) Jan Felix Drexler et al.   Nature Communications

Structure of the Ulster Strain Newcastle Disease Virus Hemagglutinin-Neuraminidase Reveals Auto-Inhibitory Interactions Associated with Low Virulence

(2012) Ping Yuan et al.   PLoS Pathogens

Cedar Virus: A Novel Henipavirus Isolated from Australian Bats

(2012) Glenn A. Marsh et al.   PLoS Pathogens

Premature Activation of the Paramyxovirus Fusion Protein before Target Cell Attachment with Corruption of the Viral Fusion Machinery

(2011) Shohreh F. Farzan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes

(2011) J. S. McLellan et al.   JOURNAL OF VIROLOGY

Spring-Loaded Model Revisited: Paramyxovirus Fusion Requires Engagement of a Receptor Binding Protein beyond Initial Triggering of the Fusion Protein

(2011) M. Porotto et al.   JOURNAL OF VIROLOGY

Structure and Mutagenesis of the Parainfluenza Virus 5 Hemagglutinin-Neuraminidase Stalk Domain Reveals a Four-Helix Bundle and the Role of the Stalk in Fusion Promotion

(2011) S. Bose et al.   JOURNAL OF VIROLOGY

The heads of the measles virus attachment protein move to transmit the fusion-triggering signal

(2011) Chanakha K Navaratnarajah et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers

(2011) K. A. Swanson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Capture and imaging of a prehairpin fusion intermediate of the paramyxovirus PIV5

(2011) Y. H. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a four-helix bundle stalk

(2011) P. Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dimeric Architecture of the Hendra Virus Attachment Glycoprotein: Evidence for a Conserved Mode of Assembly

(2010) T. A. Bowden et al.   JOURNAL OF VIROLOGY

Blue Native PAGE and Biomolecular Complementation Reveal a Tetrameric or Higher-Order Oligomer Organization of the Physiological Measles Virus Attachment Protein H

(2010) M. A. Brindley et al.   JOURNAL OF VIROLOGY

Structure of the Newcastle disease virus F protein in the post-fusion conformation

(2010) Kurt Swanson et al.   VIROLOGY

Influenza Virus Vaccine Based on the Conserved Hemagglutinin Stalk Domain

(2010) J. Steel et al.   mBio

Glycoprotein interactions in paramyxovirus fusion

(2009) Ronald M Iorio et al.   Future Virology

Probing the Spatial Organization of Measles Virus Fusion Complexes

(2009) T. Paal et al.   JOURNAL OF VIROLOGY

Bimolecular Complementation of Paramyxovirus Fusion and Hemagglutinin-Neuraminidase Proteins Enhances Fusion: Implications for the Mechanism of Fusion Triggering

(2009) S. A. Connolly et al.   JOURNAL OF VIROLOGY

Structure of the measles virus hemagglutinin bound to the CD46 receptor

(2009) César Santiago et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Novel Receptor-induced Activation Site in the Nipah Virus Attachment Glycoprotein (G) Involved in Triggering the Fusion Glycoprotein (F)

(2008) Hector C. Aguilar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Interaction between Paramyxovirus Fusion and Attachment Proteins

(2008) Jin K. Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Residues in the Stalk Domain of the Hendra Virus G Glycoprotein Modulate Conformational Changes Associated with Receptor Binding

(2008) K. A. Bishop et al.   JOURNAL OF VIROLOGY

Crystal Structure and Carbohydrate Analysis of Nipah Virus Attachment Glycoprotein: a Template for Antiviral and Vaccine Design

(2008) T. A. Bowden et al.   JOURNAL OF VIROLOGY

Structural basis of Nipah and Hendra virus attachment to their cell-surface receptor ephrin-B2

(2008) Thomas A Bowden et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Host cell recognition by the henipaviruses: Crystal structures of the Nipah G attachment glycoprotein and its complex with ephrin-B3

(2008) K. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Domain architecture and oligomerization properties of the paramyxovirus PIV 5 hemagglutinin-neuraminidase (HN) protein

(2008) Ping Yuan et al.   VIROLOGY