Changes in Protein Domains outside the Catalytic Site of the Bacteriophage Q  Replicase Reduce the Mutagenic Effect of 5-Azacytidine

Evolution at increased error rate leads to the coexistence of multiple adaptive pathways in an RNA virus

(2013) Laura Cabanillas et al.   BMC EVOLUTIONARY BIOLOGY

Correlation Between Mutation Rate and Genome Size in Riboviruses: Mutation Rate of Bacteriophage Q 

(2013) K. Bradwell et al.   GENETICS

Biomedical implications of viral mutation and evolution

(2012) Rafael Sanjuán et al.   Future Virology

A Polymerase Mechanism-based Strategy for Viral Attenuation and Vaccine Development

(2012) Spencer A. Weeks et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleoside Analogue Mutagenesis of a Single-Stranded DNA Virus: Evolution and Resistance

(2012) Pilar Domingo-Calap et al.   JOURNAL OF VIROLOGY

Coxsackievirus B3 mutator strains are attenuated in vivo

(2012) N. F. Gnadig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Three Faces of Riboviral Spontaneous Mutation: Spectrum, Mode of Genome Replication, and Mutation Rate

(2012) Libertad García-Villada et al.   PLoS Genetics

Ribavirin Can Be Mutagenic for Arenaviruses

(2011) H. Moreno et al.   JOURNAL OF VIROLOGY

Azacytidine and Decitabine Induce Gene-Specific and Non-Random DNA Demethylation in Human Cancer Cell Lines

(2011) Sabine Hagemann et al.   PLoS One

Arbovirus high fidelity variant loses fitness in mosquitoes and mice

(2011) L. L. Coffey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of mutations conferring 5-azacytidine resistance in bacteriophage Qβ

(2011) María Arribas et al.   VIROLOGY

Isolation of Fidelity Variants of RNA Viruses and Characterization of Virus Mutation Frequency

(2011) Stéphanie Beaucourt et al.   Jove-Journal of Visualized Experiments

Structure of Foot-and-Mouth Disease Virus Mutant Polymerases with Reduced Sensitivity to Ribavirin

(2010) C. Ferrer-Orta et al.   JOURNAL OF VIROLOGY

Structure of the Q  replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins

(2010) R. T. Kidmose et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Assembly of Q  viral RNA polymerase with host translational elongation factors EF-Tu and -Ts

(2010) D. Takeshita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase

(2010) P. Gong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-Escape

(2010) Rubén Agudo et al.   PLoS Pathogens

Fidelity Variants of RNA Dependent RNA Polymerases Uncover an Indirect, Mutagenic Activity of Amiloride Compounds

(2010) Laura I. Levi et al.   PLoS Pathogens

Dynamics: the missing link between structure and function of the viral RNA-dependent RNA polymerase?

(2009) Craig E Cameron et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

5-Azacytidine Can Induce Lethal Mutagenesis in Human Immunodeficiency Virus Type 1

(2009) M. J. Dapp et al.   JOURNAL OF VIROLOGY

Beneficial Effects of Population Bottlenecks in an RNA Virus Evolving at Increased Error Rate

(2008) Clara Cases-González et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Domains within the 3' Untranslated Region of Turnip Crinkle Virus

(2008) J. C. McCormack et al.   JOURNAL OF VIROLOGY

Determinants of RNA-Dependent RNA Polymerase (In)fidelity Revealed by Kinetic Analysis of the Polymerase Encoded by a Foot-and-Mouth Disease Virus Mutant with Reduced Sensitivity to Ribavirin

(2008) A. Arias et al.   JOURNAL OF VIROLOGY

RNA cytosine methylation analysis by bisulfite sequencing

(2008) M. Schaefer et al.   NUCLEIC ACIDS RESEARCH