Bindarit, an Inhibitor of Monocyte Chemotactic Protein Synthesis, Protects against Bone Loss Induced by Chikungunya Virus Infection

Effects of the MCP-1 synthesis inhibitor bindarit on tumorigenesis and inflammatory markers in the C3(1)/SV40Tag mouse model of breast cancer

(2014) J.L. Steiner et al.   CYTOKINE

CCR2 Deficiency Promotes Exacerbated Chronic Erosive Neutrophil-Dominated Chikungunya Virus Arthritis

(2014) Y. S. Poo et al.   JOURNAL OF VIROLOGY

Arthritogenic alphaviral infection perturbs osteoblast function and triggers pathologic bone loss

(2014) W. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-interleukin-6 receptor antibody prevents systemic bone mass loss via reducing the number of osteoclast precursors in bone marrow in a collagen-induced arthritis model

(2013) Keisuke Tanaka et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Activated human T cells express alternative mRNA transcripts encoding a secreted form of RANKL

(2013) N C Walsh et al.   GENES AND IMMUNITY

Association of systemic and intra-articular osteoclastogenic potential, pro-inflammatory mediators and disease activity with the form of inflammatory arthritis

(2013) Marina Ikić et al.   INTERNATIONAL ORTHOPAEDICS

Impaired bone formation and increased osteoclastogenesis in mice lacking chemokine (C-C motif) ligand 5 (Ccl5)

(2013) Kristofer Wintges et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Physiological Functions of Osteoblast Lineage and T Cell-Derived RANKL in Bone Homeostasis

(2013) Toshio Fumoto et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Osteoclastogenesis induced by CHIKV-infected fibroblast-like synoviocytes: A possible interplay between synoviocytes and monocytes/macrophages in CHIKV-induced arthralgia/arthritis

(2013) Weerawat Phuklia et al.   VIRUS RESEARCH

Serumβ-Catenin Levels Associated with the Ratio of RANKL/OPG in Patients with Postmenopausal Osteoporosis

(2013) Xiao-Juan Xu et al.   International Journal of Endocrinology

Reciprocal Activation of CD4+ T Cells and Synovial Fibroblasts by Stromal Cell-Derived Factor 1 Promotes RANKL Expression and Osteoclastogenesis in Rheumatoid Arthritis

(2013) Hae-Rim Kim et al.   Arthritis & Rheumatology

Bindarit

(2012) Eugenio Mora et al.   CELL CYCLE

Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee

(2012) David W Dempster et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Interleukin 6, RANKL, and Osteoprotegerin Expression by Chikungunya Virus-Infected Human Osteoblasts

(2012) M. Noret et al.   JOURNAL OF INFECTIOUS DISEASES

The CCL2 synthesis inhibitor bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis

(2012) Shujun Ge et al.   Journal of Neuroinflammation

RANTES, MCP-1 chemokines and factors describing rheumatoid arthritis

(2012) Monika Pavkova Goldbergova et al.   MOLECULAR IMMUNOLOGY

Inflammatory bone loss: pathogenesis and therapeutic intervention

(2012) Kurt Redlich et al.   NATURE REVIEWS DRUG DISCOVERY

Antiproteinuric Effect of Chemokine C-C Motif Ligand 2 Inhibition in Subjects with Acute Proliferative Lupus Nephritis

(2011) Alessandro Ble et al.   AMERICAN JOURNAL OF NEPHROLOGY

A Mouse Model of Chikungunya Virus–Induced Musculoskeletal Inflammatory Disease

(2011) Thomas E. Morrison et al.   AMERICAN JOURNAL OF PATHOLOGY

The genetics of alphaviruses

(2011) Suan Sin Foo et al.   Future Virology

Protection From Arthritis and Myositis in a Mouse Model of Acute Chikungunya Virus Disease by Bindarit, an Inhibitor of Monocyte Chemotactic Protein-1 Synthesis

(2011) Nestor E. Rulli et al.   JOURNAL OF INFECTIOUS DISEASES

Inflammatory Cytokine Expression Is Associated with Chikungunya Virus Resolution and Symptom Severity

(2011) Alyson A. Kelvin et al.   PLoS Neglected Tropical Diseases

Baseline RANKL:OPG ratio and markers of bone and cartilage degradation predict annual radiological progression over 11 years in rheumatoid arthritis

(2010) L. H. D. van Tuyl et al.   ANNALS OF THE RHEUMATIC DISEASES

Chikungunya disease in nonhuman primates involves long-term viral persistence in macrophages

(2010) Karine Labadie et al.   JOURNAL OF CLINICAL INVESTIGATION

Active Infection of Human Blood Monocytes by Chikungunya Virus Triggers an Innate Immune Response

(2010) Z. Her et al.   JOURNAL OF IMMUNOLOGY

Persistent Chronic Inflammation and Infection by Chikungunya Arthritogenic Alphavirus in Spite of a Robust Host Immune Response

(2010) J. J. Hoarau et al.   JOURNAL OF IMMUNOLOGY

Persistent Arthralgia Induced by Chikungunya Virus Infection is Associated with Interleukin-6 and Granulocyte Macrophage Colony-Stimulating Factor

(2010) Angela Chow et al.   JOURNAL OF INFECTIOUS DISEASES

Chikungunya Virus Arthritis in Adult Wild-Type Mice

(2010) J. Gardner et al.   JOURNAL OF VIROLOGY

Different Effects of the Different Natural CC Chemokine Receptor 2b Ligands on  -Arrestin Recruitment, G i Signaling, and Receptor Internalization

(2010) Y. A. Berchiche et al.   MOLECULAR PHARMACOLOGY

Serum RANKL, osteoprotegerin (OPG), and RANKL/OPG ratio in nephrotic children

(2010) Anna Wasilewska et al.   PEDIATRIC NEPHROLOGY

Natural killer cells trigger osteoclastogenesis and bone destruction in arthritis

(2010) K. Soderstrom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical progression of chikungunya fever during acute and chronic arthritic stages and the changes in joint morphology as revealed by imaging

(2010) Sathya Prakash Manimunda et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Rheumatoid arthritis after Chikungunya fever: a prospective follow-up study of 21 cases

(2009) E Bouquillard et al.   ANNALS OF THE RHEUMATIC DISEASES

Amelioration of alphavirus-induced arthritis and myositis in a mouse model by treatment with bindarit, an inhibitor of monocyte chemotactic proteins

(2009) Nestor E. Rulli et al.   ARTHRITIS AND RHEUMATISM

MCP-1 expressed by osteoclasts stimulates osteoclastogenesis in an autocrine/paracrine manner

(2009) Kana Miyamoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Destructive arthritis in a patient with chikungunya virus infection with persistent specific IgM antibodies

(2009) Denis Malvy et al.   BMC INFECTIOUS DISEASES

The Chemokine Cxcl1 Is a Novel Target Gene of Parathyroid Hormone (PTH)/PTH-Related Protein in Committed Osteoblasts

(2009) Döne Onan et al.   ENDOCRINOLOGY

Bone remodeling in rheumatic disease: a question of balance

(2009) Nicole C. Walsh et al.   IMMUNOLOGICAL REVIEWS

A report of 21 cases of rheumatoid arthritis following Chikungunya fever. A mean follow-up of two years

(2009) Éric Bouquillard et al.   JOINT BONE SPINE

Factors associated with persistence of arthralgia among chikungunya virus-infected travellers: Report of 42 French cases

(2009) Sophie Larrieu et al.   JOURNAL OF CLINICAL VIROLOGY

Functions of RANKL/RANK/OPG in bone modeling and remodeling

(2008) Brendan F. Boyce et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

High levels of synovial fluid osteoprotegerin (OPG) and increased serum ratio of receptor activator of nuclear factor-κB ligand (RANKL) to OPG correlate with disease severity in patients with primary knee osteoarthritis

(2008) Anastasia Pilichou et al.   CLINICAL BIOCHEMISTRY

Treatment with bindarit, an inhibitor of MCP-1 synthesis, protects mice against trinitrobenzene sulfonic acid-induced colitis

(2008) M. Bhatia et al.   INFLAMMATION RESEARCH

Vicious cycle between myeloma cell binding to bone marrow stromal cells via VLA-4–VCAM-1 adhesion and macrophage inflammatory protein-1α and MIP-1β production

(2008) Masahiro Abe et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Macrophage‐Derived Proinflammatory Factors Contribute to the Development of Arthritis and Myositis after Infection with an Arthrogenic Alphavirus

(2008) Brett A. Lidbury et al.   JOURNAL OF INFECTIOUS DISEASES

Connective tissue metabolism in chikungunya patients

(2008) Sudarsanareddy Lokireddy et al.   Virology Journal