Ribavirin-Resistant Variants of Foot-and-Mouth Disease Virus: the Effect of Restricted Quasispecies Diversity on Viral Virulence

An increased replication fidelity mutant of foot-and-mouth disease virus retains fitness in vitro and virulence in vivo

(2013) Jianxiong Zeng et al.   ANTIVIRAL RESEARCH

A Polymerase Mechanism-based Strategy for Viral Attenuation and Vaccine Development

(2012) Spencer A. Weeks et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inoculation of newborn mice with non-coding regions of foot-and-mouth disease virus RNA can induce a rapid, solid and wide-range protection against viral infection

(2011) Miguel Rodríguez-Pulido et al.   ANTIVIRAL RESEARCH

Mutational Robustness of an RNA Virus Influences Sensitivity to Lethal Mutagenesis

(2011) J. D. Graci et al.   JOURNAL OF VIROLOGY

Arbovirus high fidelity variant loses fitness in mosquitoes and mice

(2011) L. L. Coffey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isolation of Fidelity Variants of RNA Viruses and Characterization of Virus Mutation Frequency

(2011) Stéphanie Beaucourt et al.   Jove-Journal of Visualized Experiments

Poliovirus Polymerase Residue 5 Plays a Critical Role in Elongation Complex Stability

(2010) S. E. Hobdey et al.   JOURNAL OF VIROLOGY

Identification of a conformational epitope on the VP1 G-H Loop of type Asia1 foot-and-mouth disease virus defined by a protective monoclonal antibody

(2010) Haiwei Wang et al.   VETERINARY MICROBIOLOGY

Quasispecies Theory and the Behavior of RNA Viruses

(2010) Adam S. Lauring et al.   PLoS Pathogens

A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-Escape

(2010) Rubén Agudo et al.   PLoS Pathogens

Fidelity Variants of RNA Dependent RNA Polymerases Uncover an Indirect, Mutagenic Activity of Amiloride Compounds

(2010) Laura I. Levi et al.   PLoS Pathogens

Validation of two real-time RT-PCR methods for foot-and-mouth disease diagnosis: RNA-extraction, matrix effect, uncertainty of measurement and precision

(2009) Nesya Goris et al.   JOURNAL OF VIROLOGICAL METHODS

Differences in the virulence of two strains of Foot-and-Mouth Disease Virus Serotype A with the same spatiotemporal distribution

(2009) Soledad García-Nuñez et al.   VIRUS RESEARCH

Tolerance to mutations in the foot-and-mouth disease virus integrin-binding RGD region is different in cultured cells and in vivo and depends on the capsid sequence context

(2008) M. Gutierrez-Rivas et al.   JOURNAL OF GENERAL VIROLOGY

Crystal Structure of Coxsackievirus B3 3Dpol Highlights the Functional Importance of Residue 5 in Picornavirus Polymerases

(2008) G. Campagnola et al.   JOURNAL OF VIROLOGY

Determinants of RNA-Dependent RNA Polymerase (In)fidelity Revealed by Kinetic Analysis of the Polymerase Encoded by a Foot-and-Mouth Disease Virus Mutant with Reduced Sensitivity to Ribavirin

(2008) A. Arias et al.   JOURNAL OF VIROLOGY

Engineering attenuated virus vaccines by controlling replication fidelity

(2008) Marco Vignuzzi et al.   NATURE MEDICINE

No evidence of selection for mutational robustness during lethal mutagenesis of lymphocytic choriomeningitis virus

(2008) Verónica Martín et al.   VIROLOGY