Structural Flexibility of a Conserved Antigenic Region in Hepatitis C Virus Glycoprotein E2 Recognized by Broadly Neutralizing Antibodies
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Structural Flexibility of a Conserved Antigenic Region in Hepatitis C Virus Glycoprotein E2 Recognized by Broadly Neutralizing Antibodies
Authors
Keywords
-
Journal
JOURNAL OF VIROLOGY
Volume 89, Issue 4, Pages 2170-2181
Publisher
American Society for Microbiology
Online
2014-12-04
DOI
10.1128/jvi.02190-14
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The past, present and future of neutralizing antibodies for hepatitis C virus
- (2014) Jonathan K. Ball et al. ANTIVIRAL RESEARCH
- Flexibility in Surface-Exposed Loops in a Virus Capsid Mediates Escape from Antibody Neutralization
- (2014) A. O. Kolawole et al. JOURNAL OF VIROLOGY
- Structure of the core ectodomain of the hepatitis C virus envelope glycoprotein 2
- (2014) Abdul Ghafoor Khan et al. NATURE
- Discrete conformations of epitope II on the hepatitis C virus E2 protein for antibody-mediated neutralization and nonneutralization
- (2014) L. Deng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An alpaca nanobody inhibits hepatitis C virus entry and cell-to-cell transmission
- (2013) Alexander W. Tarr et al. HEPATOLOGY
- Reversion of Somatic Mutations of the Respiratory Syncytial Virus-Specific Human Monoclonal Antibody Fab19 Reveal a Direct Relationship between Association Rate and Neutralizing Potency
- (2013) J. T. Bates et al. JOURNAL OF IMMUNOLOGY
- Glycan Shifting on Hepatitis C Virus (HCV) E2 Glycoprotein Is a Mechanism for Escape from Broadly Neutralizing Antibodies
- (2013) Homer Pantua et al. JOURNAL OF MOLECULAR BIOLOGY
- HCV direct-acting antiviral agents: the best interferon-free combinations
- (2013) Raymond Schinazi et al. LIVER INTERNATIONAL
- Structural evidence for a bifurcated mode of action in the antibody-mediated neutralization of hepatitis C virus
- (2013) L. Deng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hepatitis C Virus E2 Envelope Glycoprotein Core Structure
- (2013) L. Kong et al. SCIENCE
- Structural Basis of HCV Neutralization by Human Monoclonal Antibodies Resistant to Viral Neutralization Escape
- (2013) Thomas Krey et al. PLoS Pathogens
- Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization
- (2012) Laura E. McCoy et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody
- (2012) J. A. Potter et al. JOURNAL OF VIROLOGY
- Structure of Hepatitis C Virus Envelope Glycoprotein E2 Antigenic Site 412 to 423 in Complex with Antibody AP33
- (2012) L. Kong et al. JOURNAL OF VIROLOGY
- Increased Antibody Affinity Confers Broad In Vitro Protection against Escape Mutants of Severe Acute Respiratory Syndrome Coronavirus
- (2012) M. Rani et al. JOURNAL OF VIROLOGY
- Cooperativity in Virus Neutralization by Human Monoclonal Antibodies to Two Adjacent Regions Located at the Amino Terminus of Hepatitis C Virus E2 Glycoprotein
- (2012) Z. Keck et al. JOURNAL OF VIROLOGY
- Broad and potent neutralization of HIV-1 by a gp41-specific human antibody
- (2012) Jinghe Huang et al. NATURE
- Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1
- (2012) L. Kong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Human Monoclonal Antibodies to a Novel Cluster of Conformational Epitopes on HCV E2 with Resistance to Neutralization Escape in a Genotype 2a Isolate
- (2012) Zhen-yong Keck et al. PLoS Pathogens
- Affinity Maturation to Improve Human Monoclonal Antibody Neutralization Potency and Breadth against Hepatitis C Virus
- (2011) Yong Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neutralizing Monoclonal Antibodies against Hepatitis C Virus E2 Protein Bind Discontinuous Epitopes and Inhibit Infection at a Postattachment Step
- (2011) M. C. Sabo et al. JOURNAL OF VIROLOGY
- Hepatitis C Patient-Derived Glycoproteins Exhibit Marked Differences in Susceptibility to Serum Neutralizing Antibodies: Genetic Subtype Defines Antigenic but Not Neutralization Serotype
- (2011) A. W. Tarr et al. JOURNAL OF VIROLOGY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Mutations within a Conserved Region of the Hepatitis C Virus E2 Glycoprotein That Influence Virus-Receptor Interactions and Sensitivity to Neutralizing Antibodies
- (2010) S. Dhillon et al. JOURNAL OF VIROLOGY
- Hepatitis C Virus Hypervariable Region 1 Modulates Receptor Interactions, Conceals the CD81 Binding Site, and Protects Conserved Neutralizing Epitopes
- (2010) D. Bankwitz et al. JOURNAL OF VIROLOGY
- Hypervariable Region 1 Differentially Impacts Viability of Hepatitis C Virus Strains of Genotypes 1 to 6 and Impairs Virus Neutralization
- (2010) J. Prentoe et al. JOURNAL OF VIROLOGY
- Efficient method for production of high yields of Fab fragments in Drosophila S2 cells
- (2010) M. Backovic et al. PROTEIN ENGINEERING DESIGN & SELECTION
- The Disulfide Bonds in Glycoprotein E2 of Hepatitis C Virus Reveal the Tertiary Organization of the Molecule
- (2010) Thomas Krey et al. PLoS Pathogens
- Identification and Characterization of Broadly Neutralizing Human Monoclonal Antibodies Directed against the E2 Envelope Glycoprotein of Hepatitis C Virus
- (2009) T. J. Broering et al. JOURNAL OF VIROLOGY
- A Point Mutation Leading to Hepatitis C Virus Escape from Neutralization by a Monoclonal Antibody to a Conserved Conformational Epitope
- (2008) Z.-Y. Keck et al. JOURNAL OF VIROLOGY
- In vitro selection of a neutralization-resistant hepatitis C virus escape mutant
- (2008) M. Gal-Tanamy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More