Prime-Boost Immunization Strategies against Chikungunya Virus

Chikungunya outbreak in the Caribbean region, December 2013 to March 2014, and the significance for Europe

(2014) W Van Bortel et al.   Eurosurveillance

A Novel Poxvirus-Based Vaccine, MVA-CHIKV, Is Highly Immunogenic and Protects Mice against Chikungunya Infection

(2014) J. Garcia-Arriaza et al.   JOURNAL OF VIROLOGY

Glucopyranosyl Lipid A Adjuvant Significantly Enhances HIV Specific T and B Cell Responses Elicited by a DNA-MVA-Protein Vaccine Regimen

(2014) Paul F. McKay et al.   PLoS One

Unique Epitopes Recognized by Antibodies Induced in Chikungunya Virus-Infected Non-Human Primates: Implications for the Study of Immunopathology and Vaccine Development

(2014) Yiu-Wing Kam et al.   PLoS One

Deliberate Attenuation of Chikungunya Virus by Adaptation to Heparan Sulfate-Dependent Infectivity: A Model for Rational Arboviral Vaccine Design

(2014) Christina L. Gardner et al.   PLoS Neglected Tropical Diseases

Complex Correlates of Protection After Vaccination

(2013) S. A. Plotkin   CLINICAL INFECTIOUS DISEASES

An Essential Role of Antibodies in the Control of Chikungunya Virus Infection

(2013) F.-M. Lum et al.   JOURNAL OF IMMUNOLOGY

Chikungunya Virus Host Range E2 Transmembrane Deletion Mutants Induce Protective Immunity against Challenge in C57BL/6J Mice

(2013) A. Piper et al.   JOURNAL OF VIROLOGY

Novel Attenuated Chikungunya Vaccine Candidates Elicit Protective Immunity in C57BL/6 mice

(2013) D. Hallengard et al.   JOURNAL OF VIROLOGY

Prevalence of and risk factors for chronic arthralgia and rheumatoid-like polyarthritis more than 2 years after infection with chikungunya virus

(2013) Khadijah Essackjee et al.   POSTGRADUATE MEDICAL JOURNAL

Chikungunya virus-like particles are more immunogenic in a lethal AG129 mouse model compared to glycoprotein E1 or E2 subunits

(2013) Stefan W. Metz et al.   VACCINE

Deciphering the protective role of adaptive immunity to CHIKV/IRES a novel candidate vaccine against Chikungunya in the A129 mouse model

(2013) Haiyan Chu et al.   VACCINE

A recombinant measles vaccine expressing chikungunya virus-like particles is strongly immunogenic and protects mice from lethal challenge with chikungunya virus

(2013) Samantha Brandler et al.   VACCINE

Immune enhancing properties of the novel Matrix-M™ adjuvant leads to potentiated immune responses to an influenza vaccine in mice

(2013) Sofia E. Magnusson et al.   VACCINE

Virus replicon particle based Chikungunya virus neutralization assay using Gaussia luciferase as readout

(2013) Sabine Gläsker et al.   Virology Journal

Effective Chikungunya Virus-like Particle Vaccine Produced in Insect Cells

(2013) Stefan W. Metz et al.   PLoS Neglected Tropical Diseases

Nomenclature for Immune Correlates of Protection After Vaccination

(2012) S. A. Plotkin et al.   CLINICAL INFECTIOUS DISEASES

Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein

(2012) Yiu-Wing Kam et al.   EMBO Molecular Medicine

Chikungunya virus and prospects for a vaccine

(2012) Scott C Weaver et al.   Expert Review of Vaccines

Early Appearance of Neutralizing Immunoglobulin G3 Antibodies Is Associated With Chikungunya Virus Clearance and Long-term Clinical Protection

(2012) Yiu-Wing Kam et al.   JOURNAL OF INFECTIOUS DISEASES

Longitudinal Analysis of the Human Antibody Response to Chikungunya Virus Infection: Implications for Serodiagnosis and Vaccine Development

(2012) Y.-W. Kam et al.   JOURNAL OF VIROLOGY

A Chimeric Vesiculo/Alphavirus Is an Effective Alphavirus Vaccine

(2012) A. Chattopadhyay et al.   JOURNAL OF VIROLOGY

A Specific Domain of the Chikungunya Virus E2 Protein Regulates Particle Formation in Human Cells: Implications for Alphavirus Vaccine Design

(2012) Wataru Akahata et al.   JOURNAL OF VIROLOGY

Superior Induction of T Cell Responses to Conserved HIV-1 Regions by Electroporated Alphavirus Replicon DNA Compared to That with Conventional Plasmid DNA Vaccine

(2012) Maria L. Knudsen et al.   JOURNAL OF VIROLOGY

Arthritogenic alphaviruses—an overview

(2012) Andreas Suhrbier et al.   Nature Reviews Rheumatology

Impaired quality of life after chikungunya virus infection: a 2-year follow-up study

(2012) E. Couturier et al.   RHEUMATOLOGY

Evaluation of recombinant E2 protein-based and whole-virus inactivated candidate vaccines against chikungunya virus

(2012) Manish Kumar et al.   VACCINE

Cross-protective immunity against o‘nyong-nyong virus afforded by a novel recombinant chikungunya vaccine

(2012) Charalambos D. Partidos et al.   VACCINE

Manipulation of immunodominant dengue virus E protein epitopes reduces potential antibody-dependent enhancement

(2012) Holly R Hughes et al.   Virology Journal

Chikungunya: a re-emerging virus

(2011) Felicity J Burt et al.   LANCET

Inhibitors of Alphavirus Entry and Replication Identified with a Stable Chikungunya Replicon Cell Line and Virus-Based Assays

(2011) Leena Pohjala et al.   PLoS One

Antibody persistence and response to 2010–2011 trivalent influenza vaccine one year after a single dose of 2009 AS03-adjuvanted pandemic H1N1 vaccine in children

(2011) Vladimir Gilca et al.   VACCINE

A complex adenovirus vaccine against chikungunya virus provides complete protection against viraemia and arthritis

(2011) Danher Wang et al.   VACCINE

Evaluation of an inactivated Ross River virus vaccine in active and passive mouse immunization models and establishment of a correlate of protection

(2011) Georg W. Holzer et al.   VACCINE

Functional processing and secretion of Chikungunya virus E1 and E2 glycoproteins in insect cells

(2011) Stefan W Metz et al.   Virology Journal

A DNA Vaccine against Chikungunya Virus Is Protective in Mice and Induces Neutralizing Antibodies in Mice and Nonhuman Primates

(2011) Karthik Mallilankaraman et al.   PLoS Neglected Tropical Diseases

Novel Chikungunya Vaccine Candidate with an IRES-Based Attenuation and Host Range Alteration Mechanism

(2011) Kenneth Plante et al.   PLoS Pathogens

Chikungunya Virus Arthritis in Adult Wild-Type Mice

(2010) J. Gardner et al.   JOURNAL OF VIROLOGY

Semliki Forest Virus-Induced Endoplasmic Reticulum Stress Accelerates Apoptotic Death of Mammalian Cells

(2010) G. Barry et al.   JOURNAL OF VIROLOGY

Host Alternation of Chikungunya Virus Increases Fitness while Restricting Population Diversity and Adaptability to Novel Selective Pressures

(2010) L. L. Coffey et al.   JOURNAL OF VIROLOGY

Glycoprotein organization of Chikungunya virus particles revealed by X-ray crystallography

(2010) James E. Voss et al.   NATURE

A virus-like particle vaccine for epidemic Chikungunya virus protects nonhuman primates against infection

(2010) Wataru Akahata et al.   NATURE MEDICINE

Biology and pathogenesis of chikungunya virus

(2010) Olivier Schwartz et al.   NATURE REVIEWS MICROBIOLOGY

Heterologous prime–boost vaccination

(2009) Shan Lu   CURRENT OPINION IN IMMUNOLOGY

Chikungunya: a bending reality

(2009) Zhisheng Her et al.   MICROBES AND INFECTION

Skin Electroporation: Effects on Transgene Expression, DNA Persistence and Local Tissue Environment

(2009) Anna-Karin Roos et al.   PLoS One

Assessment of immunogenic potential of Vero adapted formalin inactivated vaccine derived from novel ECSA genotype of Chikungunya virus

(2009) Mugdha Tiwari et al.   VACCINE

Live Chimeric and Inactivated Japanese Encephalitis Virus Vaccines Differ in Their Cross-Protective Values against Murray Valley Encephalitis Virus

(2008) M. Lobigs et al.   JOURNAL OF VIROLOGY

Chimeric alphavirus vaccine candidates for chikungunya

(2008) Eryu Wang et al.   VACCINE

Immunogenicity of novel consensus-based DNA vaccines against Chikungunya virus

(2008) Karuppiah Muthumani et al.   VACCINE