Combination of PB2 271A and SR Polymorphism at Positions 590/591 Is Critical for Viral Replication and Virulence of Swine Influenza Virus in Cultured Cells and In Vivo

Molecular Characterization of Pandemic H1N1 Influenza Viruses Isolated from Turkeys and Pathogenicity of a Human pH1N1 Isolate in Turkeys

(2010) Yohannes Berhane et al.   AVIAN DISEASES

PB2 Residue 271 Plays a Key Role in Enhanced Polymerase Activity of Influenza A Viruses in Mammalian Host Cells

(2010) K. A. Bussey et al.   JOURNAL OF VIROLOGY

Introduction of Virulence Markers in PB2 of Pandemic Swine-Origin Influenza Virus Does Not Result in Enhanced Virulence or Transmission

(2010) S. Herfst et al.   JOURNAL OF VIROLOGY

Substitution of lysine at 627 position in PB2 protein does not change virulence of the 2009 pandemic H1N1 virus in mice

(2010) Huachen Zhu et al.   VIROLOGY

Pathogenicity of swine influenza viruses possessing an avian or swine-origin PB2 polymerase gene evaluated in mouse and pig models

(2010) Wenjun Ma et al.   VIROLOGY

The PB2-E627K Mutation Attenuates Viruses Containing the 2009 H1N1 Influenza Pandemic Polymerase

(2010) B. W. Jagger et al.   mBio

Biological and Structural Characterization of a Host-Adapting Amino Acid in Influenza Virus

(2010) Shinya Yamada et al.   PLoS Pathogens

NS2/NEP protein regulates transcription and replication of the influenza virus RNA genome

(2009) Nicole C. Robb et al.   JOURNAL OF GENERAL VIROLOGY

Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic

(2009) Gavin J. D. Smith et al.   NATURE

Adaptive strategies of the influenza virus polymerase for replication in humans

(2009) Andrew Mehle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transmission of Influenza Virus in a Mammalian Host Is Increased by PB2 Amino Acids 627K or 627E/701N

(2009) John Steel et al.   PLoS Pathogens