Virulence Determinants of Pandemic A(H1N1)2009 Influenza Virus in a Mouse Model

The 2009 Pandemic H1N1 D222G Hemagglutinin Mutation Alters Receptor Specificity and Increases Virulence in Mice but Not in Ferrets

(2011) Yacine Abed et al.   JOURNAL OF INFECTIOUS DISEASES

Avian-Type Receptor-Binding Ability Can Increase Influenza Virus Pathogenicity in Macaques

(2011) T. Watanabe et al.   JOURNAL OF VIROLOGY

Effect of D222G Mutation in the Hemagglutinin Protein on Receptor Binding, Pathogenesis and Transmissibility of the 2009 Pandemic H1N1 Influenza Virus

(2011) Jessica A. Belser et al.   PLoS One

Mutations in PA, NP, and HA of a pandemic (H1N1) 2009 influenza virus contribute to its adaptation to mice

(2011) Saori Sakabe et al.   VIRUS RESEARCH

Altered Receptor Specificity and Cell Tropism of D222G Hemagglutinin Mutants Isolated from Fatal Cases of Pandemic A(H1N1) 2009 Influenza Virus

(2010) Y. Liu et al.   JOURNAL OF VIROLOGY

Virulence-Associated Substitution D222G in the Hemagglutinin of 2009 Pandemic Influenza A(H1N1) Virus Affects Receptor Binding

(2010) S. Chutinimitkul et al.   JOURNAL OF VIROLOGY

Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection

(2010)   NEW ENGLAND JOURNAL OF MEDICINE

A single-amino-acid substitution in the HA protein changes the replication and pathogenicity of the 2009 pandemic A (H1N1) influenza viruses in vitro and in vivo

(2010) Lili Xu et al.   Virology Journal

Biological and Structural Characterization of a Host-Adapting Amino Acid in Influenza Virus

(2010) Shinya Yamada et al.   PLoS Pathogens

Structural insight into the essential PB1–PB2 subunit contact of the influenza virus RNA polymerase

(2009) Kanako Sugiyama et al.   EMBO JOURNAL

Critically Ill Patients With 2009 Influenza A(H1N1) Infection in Canada

(2009) Anand Kumar   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Factors Associated With Death or Hospitalization Due to Pandemic 2009 Influenza A(H1N1) Infection in California

(2009) Janice K. Louie   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Emergence of a novel swine-origin influenza A virus (S-OIV) H1N1 virus in humans

(2009) J.S. Malik Peiris et al.   JOURNAL OF CLINICAL VIROLOGY

Hospitalized Patients with 2009 H1N1 Influenza in the United States, April–June 2009

(2009) Seema Jain et al.   NEW ENGLAND JOURNAL OF MEDICINE

Adaptive strategies of the influenza virus polymerase for replication in humans

(2009) Andrew Mehle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pandemic Potential of a Strain of Influenza A (H1N1): Early Findings

(2009) C. Fraser et al.   SCIENCE

Antigenic and Genetic Characteristics of Swine-Origin 2009 A(H1N1) Influenza Viruses Circulating in Humans

(2009) R. J. Garten et al.   SCIENCE

The structural basis for cap binding by influenza virus polymerase subunit PB2

(2008) Delphine Guilligay et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY