Naturally Occurring Swine Influenza A Virus PB1-F2 Phenotypes That Contribute to Superinfection with Gram-Positive Respiratory Pathogens

Letter to the editor. Group A streptococcal infections during the seasonal influenza outbreak 2010/11 in South East England

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Flu surveillance lacking

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Pause on Avian Flu Transmission Research

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Correlates of vaccine protection from influenza and its complications

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Immunotherapy with a Combination of Intravenous Immune Globulin and P4 Peptide Rescues Mice from Postinfluenza Pneumococcal Pneumonia

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The influenza virus PB1-F2 protein has interferon antagonistic activity

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Invasive Bacterial Infections in Relation to Influenza Outbreaks, 2006–2010

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The pathogenesis of influenza virus infections: the contributions of virus and host factors

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Influenza Virus Primes Mice for Pneumonia From Staphylococcus aureus

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Immunopathogenic and Antibacterial Effects of H3N2 Influenza A Virus PB1-F2 Map to Amino Acid Residues 62, 75, 79, and 82

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Impact of Amino Acid Mutations in PB2, PB1-F2, and NS1 on the Replication and Pathogenicity of Pandemic (H1N1) 2009 Influenza Viruses

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The Virulence of 1997 H5N1 Influenza Viruses in the Mouse Model Is Increased by Correcting a Defect in Their NS1 Proteins

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(2011) Dhanasekaran Vijaykrishna et al.   NATURE

Inactivated and live, attenuated influenza vaccines protect mice against influenza:Streptococcus pyogenes super-infections

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Pathogenicity of different PR8 influenza A virus variants in mice is determined by both viral and host factors

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The Influenza Virus Protein PB1-F2 Inhibits the Induction of Type I Interferon at the Level of the MAVS Adaptor Protein

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Complications of seasonal and pandemic influenza

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Influenza A Virus Protein PB1-F2 Exacerbates IFN-  Expression of Human Respiratory Epithelial Cells

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Influenza Enhances Susceptibility to Natural Acquisition of and Disease due toStreptococcus pneumoniaein Ferrets

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PB2 and Hemagglutinin Mutations Are Major Determinants of Host Range and Virulence in Mouse-Adapted Influenza A Virus

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PB2 Residue 271 Plays a Key Role in Enhanced Polymerase Activity of Influenza A Viruses in Mammalian Host Cells

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A Single N66S Mutation in the PB1-F2 Protein of Influenza A Virus Increases Virulence by Inhibiting the Early Interferon Response In Vivo

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Differential Localization and Function of PB1-F2 Derived from Different Strains of Influenza A Virus

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A Detrimental Effect of Interleukin-10 on Protective Pulmonary Humoral Immunity during Primary Influenza A Virus Infection

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Association of 2009 Pandemic Influenza A (H1N1) Infection and Increased Hospitalization With Parapneumonic Empyema in Children in Utah

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The Proapoptotic Influenza A Virus Protein PB1-F2 Forms a Nonselective Ion Channel

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Highly Pathogenic H5N1 Influenza Viruses Carry Virulence Determinants beyond the Polybasic Hemagglutinin Cleavage Site

(2010) Jessica Bogs et al.   PLoS One

Reassortment of Pandemic H1N1/2009 Influenza A Virus in Swine

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Pathogenicity of swine influenza viruses possessing an avian or swine-origin PB2 polymerase gene evaluated in mouse and pig models

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The PB2-E627K Mutation Attenuates Viruses Containing the 2009 H1N1 Influenza Pandemic Polymerase

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PB1-F2 Proteins from H5N1 and 20th Century Pandemic Influenza Viruses Cause Immunopathology

(2010) Julie L. McAuley et al.   PLoS Pathogens

Phosphorylation of the influenza A virus protein PB1-F2 by PKC is crucial for apoptosis promoting functions in monocytes

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Diversity of influenza viruses in swine and the emergence of a novel human pandemic influenza A (H1N1)

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A Complicated Message: Identification of a Novel PB1-Related Protein Translated from Influenza A Virus Segment 2 mRNA

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The NS1 Protein of the 1918 Pandemic Influenza Virus Blocks Host Interferon and Lipid Metabolism Pathways

(2009) R. Billharz et al.   JOURNAL OF VIROLOGY

The Effects of Influenza A Virus PB1-F2 Protein on Polymerase Activity Are Strain Specific and Do Not Impact Pathogenesis

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Triple-Reassortant Swine Influenza A (H1) in Humans in the United States, 2005–2009

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An update on swine-origin influenza virus A/H1N1: a review

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The proapoptotic influenza A virus protein PB1-F2 regulates viral polymerase activity by interaction with the PB1 protein

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Planning for an Influenza Pandemic: Thinking beyond the Virus

(2008) Jonathan A. McCullers   JOURNAL OF INFECTIOUS DISEASES

Inhibition of pulmonary antibacterial defense by interferon-γ during recovery from influenza infection

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FDA/NIH/WHO public workshop on immune correlates of protection against influenza A viruses in support of pandemic vaccine development, Bethesda, Maryland, US, December 10–11, 2007

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