Nuclear Receptor Signaling Inhibits HIV-1 Replication in Macrophages through Multiple trans-Repression Mechanisms

Sumoylation of Peroxisome Proliferator-Activated Receptor   by Apoptotic Cells Prevents Lipopolysaccharide-Induced NCoR Removal from  B Binding Sites Mediating Transrepression of Proinflammatory Cytokines

(2014) C. Jennewein et al.   JOURNAL OF IMMUNOLOGY

Phase 1 randomized trial of the vaginal safety and acceptability of SPL7013 gel (VivaGel) in sexually active young women (MTN-004)

(2011) Ian McGowan et al.   AIDS

Drugs that prevent HIV infection

(2011) Mark A. Wainberg   NATURE

A Randomized Trial to Assess Anti-HIV Activity in Female Genital Tract Secretions and Soluble Mucosal Immunity Following Application of 1% Tenofovir Gel

(2011) Marla J. Keller et al.   PLoS One

Preclinical evaluation of anti-HIV microbicide products: New models and biomarkers

(2010) Gustavo F. Doncel et al.   ANTIVIRAL RESEARCH

Macrophage HIV-1 infection in duodenal tissue of patients on long term HAART

(2010) Alberto Zalar et al.   ANTIVIRAL RESEARCH

Suppression of human immunodeficiency virus type 1 replication in macrophages by commensal bacteria preferentially stimulating Toll-like receptor 4

(2010) N. Ahmed et al.   JOURNAL OF GENERAL VIROLOGY

Neisseria gonorrhoeae Enhances HIV-1 Infection of Primary Resting CD4+ T Cells through TLR2 Activation

(2010) J. Ding et al.   JOURNAL OF IMMUNOLOGY

Genetic Associations of Variants in Genes Encoding HIV‐Dependency Factors Required for HIV‐1 Infection

(2010) Leslie W. Chinn et al.   JOURNAL OF INFECTIOUS DISEASES

Stimulation of the Liver X Receptor Pathway Inhibits HIV-1 Replication via Induction of ATP-Binding Cassette Transporter A1

(2010) M. P. Morrow et al.   MOLECULAR PHARMACOLOGY

Molecular mechanisms of HIV-1 persistence in the monocyte-macrophage lineage

(2010) Valentin Le Douce et al.   Retrovirology

Molecular mechanisms of neuroinvasion by monocytes-macrophages in HIV-1 infection

(2010) Gabriel Gras et al.   Retrovirology

Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women

(2010) Q. Abdool Karim et al.   SCIENCE

PPARγ and LXR Signaling Inhibit Dendritic Cell-Mediated HIV-1 Capture and trans-Infection

(2010) Timothy M. Hanley et al.   PLoS Pathogens

Selective peroxisome proliferator-activated receptor γ (PPARγ) modulation as a strategy for safer therapeutic PPARγ activation

(2009) Linda Slanec Higgins et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Polyanionic Microbicides Modify Toll-Like Receptor-Mediated Cervicovaginal Immune Responses

(2009) R. T. Trifonova et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The level of monocyte turnover predicts disease progression in the macaque model of AIDS

(2009) A. Hasegawa et al.   BLOOD

15-Deoxy-Δ12,14-prostaglandin J2 inhibits HIV-1 transactivating protein, Tat, through covalent modification

(2009) Parisa Kalantari et al.   FASEB JOURNAL

Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

(2009) S. Ghisletti et al.   GENES & DEVELOPMENT

Safety, Pharmacokinetics, and Pharmacodynamics of Single Doses of LXR-623, a Novel Liver X-Receptor Agonist, in Healthy Participants

(2009) Arie Katz et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Macrophages in Vaginal but Not Intestinal Mucosa Are Monocyte-Like and Permissive to Human Immunodeficiency Virus Type 1 Infection

(2009) R. Shen et al.   JOURNAL OF VIROLOGY

Elevated concentrations of 15-deoxy-Δ12,14-prostaglandin J2in chronic liver disease propose therapeutic trials with peroxisome proliferator activated receptor γ-inducing drugs

(2009) Olav A. Gressner et al.   LIVER INTERNATIONAL

Interactions of oxysterols with membranes and proteins

(2009) Vesa M. Olkkonen et al.   MOLECULAR ASPECTS OF MEDICINE

Differential SUMOylation of LXRα and LXRβ Mediates Transrepression of STAT1 Inflammatory Signaling in IFN-γ-Stimulated Brain Astrocytes

(2009) Jee Hoon Lee et al.   MOLECULAR CELL

TLR2 and TLR4 triggering exerts contrasting effects with regard to HIV-1 infection of human dendritic cells and subsequent virus transfer to CD4+ T cells

(2009) Sandra Thibault et al.   Retrovirology

Inhibition of extracellular signal-regulated kinase (ERK) signaling participates in repression of nuclear factor (NF)-κB activity by glucocorticoids

(2008) Lars-Göran Bladh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cellular Reservoirs of HIV-1 and their Role in Viral Persistence

(2008) Aikaterini Alexaki et al.   CURRENT HIV RESEARCH

PPAR Modulators and PPAR Pan Agonists for Metabolic Diseases: The Next Generation of Drugs Targeting Peroxisome Proliferator-Activated Receptors?

(2008) P. Feldman et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Relationship between Levels of Inflammatory Cytokines in the Genital Tract and CD4+Cell Counts in Women with Acute HIV‐1 Infection

(2008) Lisa M. Bebell et al.   JOURNAL OF INFECTIOUS DISEASES

Monocyte/macrophage trafficking in acquired immunodeficiency syndrome encephalitis: Lessons from human and nonhuman primate studies

(2008) Tracy Fischer-Smith et al.   JOURNAL OF NEUROVIROLOGY

Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells

(2008) Elizabeth A DiBlasio-Smith et al.   Journal of Translational Medicine

Efficacy of Carraguard for prevention of HIV infection in women in South Africa: a randomised, double-blind, placebo-controlled trial

(2008) Stephanie Skoler-Karpoff et al.   LANCET

Ligand-selective transactivation and transrepression via the glucocorticoid receptor: Role of cofactor interaction

(2008) Katharina Ronacher et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Expression of proinflammatory cytokines and its relationship with virus infection in the brain of macaques inoculated with macrophage-tropic simian immunodeficiency virus

(2008) Hui Qin Xing et al.   NEUROPATHOLOGY

Topical application of entry inhibitors as "virustats" to prevent sexual transmission of HIV infection

(2008) Michael M Lederman et al.   Retrovirology

PGJ2 antagonizes NF-κB-induced HIV-1 LTR activation in colonic epithelial cells

(2008) Mélissa Boisvert et al.   VIROLOGY

TLR2-mediated cell stimulation in bacterial vaginosis

(2007) Debra Mares et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY