Possible Mechanical Roles of Glycosaminoglycans in Thoracic Aortic Dissection and Associations with Dysregulated Transforming Growth Factor-�

Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development

(2012) Lars Maegdefessel et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNAs, fibrotic remodeling, and aortic aneurysms

(2012) Dianna M. Milewicz   JOURNAL OF CLINICAL INVESTIGATION

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(2012) J. S. Wilson et al.   Journal of the Royal Society Interface

The National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC): Results from phase I and scientific opportunities in phase II

(2011) Barbara L. Kroner et al.   AMERICAN HEART JOURNAL

Pathogenesis of Acute Aortic Dissection: A Finite Element Stress Analysis

(2011) Derek P. Nathan et al.   ANNALS OF THORACIC SURGERY

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(2011) Marc K. Halushka   CARDIOVASCULAR PATHOLOGY

Mechanical assessment of elastin integrity in fibrillin-1-deficient carotid arteries: implications for Marfan syndrome

(2011) Jacopo Ferruzzi et al.   CARDIOVASCULAR RESEARCH

Parsing Aortic Aneurysms

(2011) Mark W. Majesky et al.   CIRCULATION RESEARCH

miR-29b Participates in Early Aneurysm Development in Marfan Syndrome

(2011) Denis R. Merk et al.   CIRCULATION RESEARCH

Aortic dissecting aneurysms—Histopathological findings

(2011) S. Bode-Jänisch et al.   FORENSIC SCIENCE INTERNATIONAL

Investigation of hemodynamics in the development of dissecting aneurysm within patient-specific dissecting aneurismal aortas using computational fluid dynamics (CFD) simulations

(2011) Kwong Ming Tse et al.   JOURNAL OF BIOMECHANICS

Matrix Metalloproteinases and Descending Aortic Aneurysms: Parity, Disparity, and Switch

(2011) Tom P. Theruvath et al.   JOURNAL OF CARDIAC SURGERY

Smad proteins differentially regulate transforming growth factor-β-mediated induction of chondroitin sulfate proteoglycans

(2011) Bala T. S. Susarla et al.   JOURNAL OF NEUROCHEMISTRY

Effect of aneurysm on the mechanical dissection properties of the human ascending thoracic aorta

(2011) Salvatore Pasta et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

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(2011) Mark E. Lindsay et al.   NATURE

Noncanonical TGF  Signaling Contributes to Aortic Aneurysm Progression in Marfan Syndrome Mice

(2011) T. M. Holm et al.   SCIENCE

TGFBR2 mutations alter smooth muscle cell phenotype and predispose to thoracic aortic aneurysms and dissections

(2010) Sakiko Inamoto et al.   CARDIOVASCULAR RESEARCH

Spontaneous arterial dissection: phenotype and molecular pathogenesis

(2010) Caspar Grond-Ginsbach et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Familial Thoracic Aortic Aneurysms and Dissections

(2010) Dong-Chuan Guo et al.   Circulation-Cardiovascular Genetics

The cell-elastin-elastase(s) interacting triade directs elastolysis

(2010) William Hornebeck   Frontiers in Bioscience-Landmark

Hyaluronan Synthesis Mediates the Fibrotic Response of Keratocytes to Transforming Growth Factor β

(2010) Naxin Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

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(2010) John A. Elefteriades et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Distribution of intimomedial tears in patients with type B aortic dissection

(2010) Ali Khoynezhad et al.   JOURNAL OF VASCULAR SURGERY

Transforming growth factor-β regulation of proteoglycan synthesis in vascular smooth muscle: Contribution to lipid binding and accelerated atherosclerosis in diabetes

(2010) Sundy N.Y. YANG et al.   Journal of Diabetes

Histopathologic Findings in Ascending Aortas From Individuals With Loeys-Dietz Syndrome (LDS)

(2009) Joseph J. Maleszewski et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

TGF-β1 Limits Plaque Growth, Stabilizes Plaque Structure, and Prevents Aortic Dilation in Apolipoprotein E-Null Mice

(2009) Andrew D. Frutkin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Long-term treatment with the AT1-receptor antagonist telmisartan inhibits biglycan accumulation in murine atherosclerosis

(2009) Nadine Nagy et al.   BASIC RESEARCH IN CARDIOLOGY

Causes and histopathology of ascending aortic disease in children and young adults

(2009) Deepali Jain et al.   CARDIOVASCULAR PATHOLOGY

Genetic Evidence for the Coordinated Regulation of Collagen Fibrillogenesis in the Cornea by Decorin and Biglycan

(2009) Guiyun Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fluid–structure interaction analysis of turbulent pulsatile flow within a layered aortic wall as related to aortic dissection

(2009) Khalil Khanafer et al.   JOURNAL OF BIOMECHANICS

Murine model of surgically induced acute aortic dissection type A

(2009) Peter Matt et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Cellular and molecular mechanisms of thoracic aortic aneurysms

(2009) Ismail El-Hamamsy et al.   Nature Reviews Cardiology

Vascular Extracellular Matrix and Arterial Mechanics

(2009) Jessica E. Wagenseil et al.   PHYSIOLOGICAL REVIEWS

Distinct defects in collagen microarchitecture underlie vessel-wall failure in advanced abdominal aneurysms and aneurysms in Marfan syndrome

(2009) J. H. N. Lindeman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intraportal administration of neuropeptide Y and hepatic glucose metabolism

(2008) Makoto Nishizawa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Reversible Secretion of Glycosaminoglycans and Proteoglycans by Cyclically Stretched Valvular Cells in 3D Culture

(2008) Vishal Gupta et al.   ANNALS OF BIOMEDICAL ENGINEERING

Intracranial and Abdominal Aortic Aneurysms: Similarities, Differences, and Need for a New Class of Computational Models

(2008) J.D. Humphrey et al.   Annual Review of Biomedical Engineering

Genetic Basis of Thoracic Aortic Aneurysms and Dissections: Focus on Smooth Muscle Cell Contractile Dysfunction

(2008) Dianna M. Milewicz et al.   Annual Review of Genomics and Human Genetics

Arterial remodeling in vascular disease: a key role for hyaluronan and versican

(2008) Thomas et al.   Frontiers in Bioscience-Landmark

Tissue diffusion and retention of metalloproteinases in ascending aortic aneurysms and dissections

(2008) Luciano F. Borges et al.   HUMAN PATHOLOGY

Dissection Properties of the Human Aortic Media: An Experimental Study

(2008) Gerhard Sommer et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Regional heterogeneity within the aorta: Relevance to aneurysm disease

(2008) Jean Marie Ruddy et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Ascending thoracic aortic aneurysms are associated with compositional remodeling and vessel stiffening but not weakening in age-matched subjects

(2008) Dimitrios C. Iliopoulos et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Transforming Growth Factor-β Signaling in Thoracic Aortic Aneurysm Development: A Paradox in Pathogenesis

(2008) Jeffrey A. Jones et al.   JOURNAL OF VASCULAR RESEARCH

Upregulation of elastase proteins results in aortic dilatation in mucopolysaccharidosis I mice

(2008) Xiucui Ma et al.   MOLECULAR GENETICS AND METABOLISM

Influence of decreasing nutrient path length on the development of engineered cartilage

(2008) L. Bian et al.   OSTEOARTHRITIS AND CARTILAGE

Variation in the histopathological features of patients with ascending aortic aneurysms: a study of 111 surgically excised cases

(2007) M J Collins et al.   JOURNAL OF CLINICAL PATHOLOGY