A lipid switch unlocks Parkinson’s disease-associated ATP13A2

Rotenone impairs autophagic flux and lysosomal functions in Parkinson’s disease

(2015) F. Wu et al.   NEUROSCIENCE

Phospholipase D1 regulates autophagic flux and clearance of α-synuclein aggregates

(2014) E-J Bae et al.   CELL DEATH AND DIFFERENTIATION

Parkinson's disease-linked human PARK9/ATP13A2 maintains zinc homeostasis and promotes α-Synuclein externalization via exosomes

(2014) Stephanie M.Y. Kong et al.   HUMAN MOLECULAR GENETICS

Parkinson's disease-associated human ATP13A2 (PARK9) deficiency causes zinc dyshomeostasis and mitochondrial dysfunction

(2014) Jin-Sung Park et al.   HUMAN MOLECULAR GENETICS

Cellular function and pathological role of ATP13A2 and related P-type transport ATPases in Parkinson's disease and other neurological disorders

(2014) Sarah van Veen et al.   Frontiers in Molecular Neuroscience

Zn2+ dyshomeostasis caused by loss of ATP13A2/PARK9 leads to lysosomal dysfunction and alpha-synuclein accumulation

(2013) Taiji Tsunemi et al.   HUMAN MOLECULAR GENETICS

Viral vectors expressing a single microRNA-based short-hairpin RNA result in potent gene silencing in vitro and in vivo

(2013) Luísa Osório et al.   JOURNAL OF BIOTECHNOLOGY

Rotenone Inhibits Autophagic Flux Prior to Inducing Cell Death

(2012) Burton J. Mader et al.   ACS Chemical Neuroscience

Lysosomal dysfunction in Parkinson disease

(2012) Benjamin Dehay et al.   Autophagy

Lysosomal dysfunction in neurodegeneration

(2012) Marija Usenovic et al.   Autophagy

Identification of novel ATP13A2 interactors and their role in α-synuclein misfolding and toxicity

(2012) Marija Usenovic et al.   HUMAN MOLECULAR GENETICS

Shadows of an Absent Partner

(2012) Gerardo R. Corradi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ca2+Induces Spontaneous Dephosphorylation of a Novel P5A-type ATPase

(2012) Danny Mollerup Sørensen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants

(2012) Jason P. Covy et al.   JOURNAL OF NEUROSCIENCE RESEARCH

ATP13A2 mutations impair mitochondrial function in fibroblasts from patients with Kufor-Rakeb syndrome

(2012) Anne Grünewald et al.   NEUROBIOLOGY OF AGING

Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration

(2012) B. Dehay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

P-Type ATPases

(2011) Michael G. Palmgren et al.   Annual Review of Biophysics

Putting the pH into phosphatidic acid signaling

(2011) John JH Shin et al.   BMC BIOLOGY

Regulation of Intracellular Manganese Homeostasis by Kufor-Rakeb Syndrome-associated ATP13A2 Protein

(2011) Jieqiong Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Depletion of PINK1 affects mitochondrial metabolism, calcium homeostasis and energy maintenance

(2011) B. Heeman et al.   JOURNAL OF CELL SCIENCE

Crystal structure of a copper-transporting PIB-type ATPase

(2011) Pontus Gourdon et al.   NATURE

ATP13A2 regulates mitochondrial bioenergetics through macroautophagy

(2011) Aaron M. Gusdon et al.   NEUROBIOLOGY OF DISEASE

Phosphatidylinositol-3,5-Bisphosphate: No Longer the Poor PIP2

(2011) Cheuk Y. Ho et al.   TRAFFIC

Structural divergence between the two subgroups of P5 ATPases

(2010) Danny Mollerup Sørensen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The secretory pathway Ca2+-ATPase 1 is associated with cholesterol-rich microdomains of human colon adenocarcinoma cells

(2010) Szilvia Baron et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome

(2010) Xian-ping Dong et al.   Nature Communications

α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

(2009) Aaron D Gitler et al.   NATURE GENETICS

Structural basis for the high Ca2+ affinity of the ubiquitous SERCA2b Ca2+ pump

(2009) I. Vandecaetsbeek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phylogenetic analysis of P5 P-type ATPases, a eukaryotic lineage of secretory pathway pumps

(2007) Annette B. Møller et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION