Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood

Partially Redundant Enhancers Cooperatively Maintain Mammalian Pomc Expression Above a Critical Functional Threshold

(2015) Daniel D. Lam et al.   PLoS Genetics

Insulin Excites Anorexigenic Proopiomelanocortin Neurons via Activation of Canonical Transient Receptor Potential Channels

(2014) Jian Qiu et al.   Cell Metabolism

Maintenance of postmitotic neuronal cell identity

(2014) Evan S Deneris et al.   NATURE NEUROSCIENCE

A High-Resolution Spatiotemporal Atlas of Gene Expression of the Developing Mouse Brain

(2014) Carol L. Thompson et al.   NEURON

Isl1 Directly Controls a Cholinergic Neuronal Identity in the Developing Forebrain and Spinal Cord by Forming Cell Type-Specific Complexes

(2014) Hyong-Ho Cho et al.   PLoS Genetics

Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity

(2013) Esteban O Mazzoni et al.   NATURE NEUROSCIENCE

Evolution of transcriptional enhancers and animal diversity

(2013) M. Rubinstein et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Enhancer turnover and conserved regulatory function in vertebrate evolution

(2013) S. Domene et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The LIM homeobox gene Isl1 is required for the correct development of the striatonigral pathway in the mouse

(2013) L. A. Ehrman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isl1 and Ldb Co-regulators of transcription are essential early determinants of mouse limb development

(2012) Ginat Narkis et al.   DEVELOPMENTAL DYNAMICS

Islet  -,  -, and  -Cell Development Is Controlled by the Ldb1 Coregulator, Acting Primarily With the Islet-1 Transcription Factor

(2012) C. S. Hunter et al.   DIABETES

Obesity-programmed mice are rescued by early genetic intervention

(2012) Viviana F. Bumaschny et al.   JOURNAL OF CLINICAL INVESTIGATION

The estrogen receptor α colocalizes with proopiomelanocortin in hypothalamic neurons and binds to a conserved motif present in the neuron-specific enhancer nPE2

(2011) Flávio S.J. de Souza et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Convergent evolution of two mammalian neuronal enhancers by sequential exaptation of unrelated retroposons

(2011) L. F. Franchini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early evolution of the LIM homeobox gene family

(2010) Mansi Srivastava et al.   BMC BIOLOGY

Differential requirements for neurogenin 3 in the development of POMC and NPY neurons in the hypothalamus

(2010) Michelle Pelling et al.   DEVELOPMENTAL BIOLOGY

Segregation of Acute Leptin and Insulin Effects in Distinct Populations of Arcuate Proopiomelanocortin Neurons

(2010) K. W. Williams et al.   JOURNAL OF NEUROSCIENCE

Phenotypic robustness conferred by apparently redundant transcriptional enhancers

(2010) Nicolás Frankel et al.   NATURE

A genomic atlas of mouse hypothalamic development

(2010) Tomomi Shimogori et al.   NATURE NEUROSCIENCE

Pet-1 is required across different stages of life to regulate serotonergic function

(2010) Chen Liu et al.   NATURE NEUROSCIENCE

Early Chordate Origins of the Vertebrate Second Heart Field

(2010) A. Stolfi et al.   SCIENCE

Distinct phases of cardiomyocyte differentiation regulate growth of the zebrafish heart

(2009) E. de Pater et al.   DEVELOPMENT

The bHLH transcription factor Hand2 is essential for the maintenance of noradrenergic properties in differentiated sympathetic neurons

(2009) Mirko Schmidt et al.   DEVELOPMENTAL BIOLOGY

Islet-1 is Required for the Maturation, Proliferation, and Survival of the Endocrine Pancreas

(2009) A. Du et al.   DIABETES

Proopiomelanocortin Expression in both GABA and Glutamate Neurons

(2009) S. T. Hentges et al.   JOURNAL OF NEUROSCIENCE

Nurr1 Is Required for Maintenance of Maturing and Adult Midbrain Dopamine Neurons

(2009) B. Kadkhodaei et al.   JOURNAL OF NEUROSCIENCE

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Cell-Autonomous Requirement for Rx Function in the Mammalian Retina and Posterior Pituitary

(2009) Olga Medina-Martinez et al.   PLoS One

Variation in Homeodomain DNA Binding Revealed by High-Resolution Analysis of Sequence Preferences

(2008) Michael F. Berger et al.   CELL