Consecutive radicalS-adenosylmethionine methylations form the ethyl side chain in thienamycin biosynthesis

Delineating the Biosynthesis of Gentamicin X2, the Common Precursor of the Gentamicin C Antibiotic Complex

(2015) Chuan Huang et al.   CHEMISTRY & BIOLOGY

Identification and Characterization of the Carbapenem MM 4550 and its Gene Cluster inStreptomyces argenteolusATCC 11009

(2014) Rongfeng Li et al.   CHEMBIOCHEM

Radical S-Adenosylmethionine Enzymes

(2014) Joan B. Broderick et al.   CHEMICAL REVIEWS

Mechanistic Diversity of RadicalS-Adenosylmethionine (SAM)-dependent Methylation

(2014) Matthew R. Bauerle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Initial characterization of Fom3 from Streptomyces wedmorensis: The methyltransferase in fosfomycin biosynthesis

(2013) Kylie D. Allen et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Computational proteomics in the post-identification era

(2013) Martin Eisenacher et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

GenK-Catalyzed C-6′ Methylation in the Biosynthesis of Gentamicin: Isolation and Characterization of a Cobalamin-Dependent Radical SAM Enzyme

(2013) Hak Joong Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thiostrepton tryptophan methyltransferase expands the chemistry of radical SAM enzymes

(2012) Stéphane Pierre et al.   Nature Chemical Biology

Metagenome Mining Reveals Polytheonamides as Posttranslationally Modified Ribosomal Peptides

(2012) M. F. Freeman et al.   SCIENCE

Radical-Mediated Enzymatic Methylation: A Tale of Two SAMS

(2011) Qi Zhang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Mutational Analysis of the Thienamycin Biosynthetic Gene Cluster fromStreptomyces cattleya

(2011) Miriam Rodríguez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Definition of the Common and Divergent Steps in Carbapenem β-Lactam Antibiotic Biosynthesis

(2011) Micah J. Bodner et al.   CHEMBIOCHEM

Biosynthetic Studies and Genetic Engineering of Pactamycin Analogs with Improved Selectivity toward Malarial Parasites

(2011) Wanli Lu et al.   CHEMISTRY & BIOLOGY

Cfr and RlmN Contain a Single [4Fe-4S] Cluster, which Directs Two Distinct Reactivities forS-Adenosylmethionine: Methyl Transfer by SN2 Displacement and Radical Generation

(2011) Tyler L. Grove et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RlmN and Cfr are Radical SAM Enzymes Involved in Methylation of Ribosomal RNA

(2010) Feng Yan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Escherichia coliAllows Efficient Modular Incorporation of Newly Isolated Quinomycin Biosynthetic Enzyme into Echinomycin Biosynthetic Pathway for Rational Design and Synthesis of Potent Antibiotic Unnatural Natural Product

(2009) Kenji Watanabe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Radical SAM Superfamily

(2008) Perry A. Frey et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Four enzymes define the incorporation of coenzyme A in thienamycin biosynthesis

(2008) M. F. Freeman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA