Mitochondrial calcium overload is a key determinant in heart failure

Ca2+ entry via Trpm2 is essential for cardiac myocyte bioenergetics maintenance

(2015) Nicholas E. Hoffman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Role of NADPH oxidase in the regulation of autophagy in cardiomyocytes

(2015) Sebastiano Sciarretta et al.   CLINICAL SCIENCE

Calcium release channel RyR2 regulates insulin release and glucose homeostasis

(2015) Gaetano Santulli et al.   JOURNAL OF CLINICAL INVESTIGATION

Assessment of cardiac function in mice lacking the mitochondrial calcium uniporter

(2015) Kira M. Holmström et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitochondrial oxidative stress promotes atrial fibrillation

(2015) Wenjun Xie et al.   Scientific Reports

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging

(2015) Gaetano Santulli et al.   Current Molecular Pharmacology

Adrenergic Signaling Regulates Mitochondrial Ca2+ Uptake Through Pyk2-Dependent Tyrosine Phosphorylation of the Mitochondrial Ca2+ Uniporter

(2014) Jin O-Uchi et al.   ANTIOXIDANTS & REDOX SIGNALING

A selective microRNA-based strategy inhibits restenosis while preserving endothelial function

(2014) Gaetano Santulli et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of metabolism in individual mitochondria during excitation–contraction coupling

(2014) Guohua Gong et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Genetically enhancing mitochondrial antioxidant activity improves muscle function in aging

(2014) Alisa Umanskaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Role of Calstabin2 in Age-related Cardiac Alterations

(2014) Qi Yuan et al.   Scientific Reports

Reactive oxygen species and redox compartmentalization

(2014) Nina Kaludercic et al.   Frontiers in Physiology

Myocardial energetics in heart failure

(2013) Alexander Nickel et al.   BASIC RESEARCH IN CARDIOLOGY

Depressing Mitochondria-Reticulum Interactions Protects Cardiomyocytes From Lethal Hypoxia-Reoxygenation Injury

(2013) Melanie Paillard et al.   CIRCULATION

Calcium cycling proteins and heart failure: mechanisms and therapeutics

(2013) Andrew R. Marks   JOURNAL OF CLINICAL INVESTIGATION

Imaging atrial arrhythmic intracellular calcium in intact heart

(2013) Wenjun Xie et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Coupling of ryanodine receptor 2 and voltage-dependent anion channel 2 is essential for Ca2+transfer from the sarcoplasmic reticulum to the mitochondria in the heart

(2012) Choon Kee Min et al.   BIOCHEMICAL JOURNAL

Bax regulates primary necrosis through mitochondrial dynamics

(2012) R. S. Whelan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Ca2+ uptake contributes to buffering cytoplasmic Ca2+ peaks in cardiomyocytes

(2012) I. Drago et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CaMK4 Gene Deletion Induces Hypertension

(2012) Gaetano Santulli et al.   Journal of the American Heart Association

Playing with Cardiac “Redox Switches”: The “HNO Way” to Modulate Cardiac Function

(2011) Carlo G. Tocchetti et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial localization unveils a novel role for GRK2 in organelle biogenesis

(2011) Anna Fusco et al.   CELLULAR SIGNALLING

The ups and downs of mitochondrial calcium signalling in the heart

(2010) Elinor J. Griffiths et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Intracardiac Injection of AdGRK5-NT Reduces Left Ventricular Hypertrophy by Inhibiting NF-κB–Dependent Hypertrophic Gene Expression

(2010) Daniela Sorriento et al.   HYPERTENSION

Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice

(2010) Jian Shan et al.   JOURNAL OF CLINICAL INVESTIGATION

Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice

(2010) John W. Elrod et al.   JOURNAL OF CLINICAL INVESTIGATION

Local control of mitochondrial membrane potential, permeability transition pore and reactive oxygen species by calcium and calmodulin in rat ventricular myocytes

(2009) Keiichi Odagiri et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The mitochondrial membrane potential and Ca2+ oscillations in smooth muscle

(2007) S. Chalmers et al.   JOURNAL OF CELL SCIENCE