Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ–RhoGEF

Class A Plexins Are Organized as Preformed Inactive Dimers on the Cell Surface

(2015) Morgan Marita et al.   BIOPHYSICAL JOURNAL

Structural mechanisms of plexin signaling

(2015) Heath G. Pascoe et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Regulated Localization Is Sufficient for Hormonal Control of Regulator of G Protein Signaling Homology Rho Guanine Nucleotide Exchange Factors (RH-RhoGEFs)

(2014) Angela M. Carter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of Crumbs tail in complex with the PALS1 PDZ–SH3–GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex

(2014) Youjun Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic dissection of plexin signaling in vivo

(2014) Thomas Worzfeld et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structures and target recognition modes of PDZ domains: recurring themes and emerging pictures

(2013) Fei Ye et al.   BIOCHEMICAL JOURNAL

Activated RhoA Is a Positive Feedback Regulator of the Lbc Family of Rho Guanine Nucleotide Exchange Factor Proteins

(2013) Frank Medina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexin

(2013) Yuxiao Wang et al.   eLife

High-Precision Isothermal Titration Calorimetry with Automated Peak-Shape Analysis

(2012) Sandro Keller et al.   ANALYTICAL CHEMISTRY

The emerging contribution of sequence context to the specificity of protein interactions mediated by PDZ domains

(2012) Katja Luck et al.   FEBS LETTERS

Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex

(2012) Bert J C Janssen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Plexins Are GTPase-Activating Proteins for Rap and Are Activated by Induced Dimerization

(2012) Y. Wang et al.   Science Signaling

Rewiring of PDZ Domain-Ligand Interaction Network Contributed to Eukaryotic Evolution

(2012) Jinho Kim et al.   PLoS Genetics

A Dual Binding Mode for RhoGTPases in Plexin Signalling

(2011) Christian H. Bell et al.   PLOS BIOLOGY

Structural Basis of Semaphorin-Plexin Recognition and Viral Mimicry from Sema7A and A39R Complexes with PlexinC1

(2010) Heli Liu et al.   CELL

Activated RhoA Binds to the Pleckstrin Homology (PH) Domain of PDZ-RhoGEF, a Potential Site for Autoregulation

(2010) Zhe Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis of semaphorin–plexin signalling

(2010) Bert J. C. Janssen et al.   NATURE

Structural basis for semaphorin signalling through the plexin receptor

(2010) Terukazu Nogi et al.   NATURE

Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEF

(2010) Zhe Chen et al.   PROTEIN SCIENCE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Selectivity of Receptor Tyrosine Kinase Signaling Is Controlled by a Secondary SH2 Domain Binding Site

(2009) Jae Hyun Bae et al.   CELL

Structure and Function of the Intracellular Region of the Plexin-B1 Transmembrane Receptor

(2009) Yufeng Tong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration

(2009) H. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conformational change upon ligand binding and dynamics of the PDZ domain from leukemia-associated Rho guanine nucleotide exchange factor

(2008) Jiangxin Liu et al.   PROTEIN SCIENCE

A Specificity Map for the PDZ Domain Family

(2008) Raffi Tonikian et al.   PLOS BIOLOGY