Structural basis for activation and non-canonical catalysis of the Rap GTPase activating protein domain of plexin

Recorded scan times can limit the accuracy of sedimentation coefficients in analytical ultracentrifugation

(2013) Huaying Zhao et al.   ANALYTICAL BIOCHEMISTRY

The role of semaphorins and their receptors in vascular development and cancer

(2013) Chenghua Gu et al.   EXPERIMENTAL CELL RESEARCH

Emerging Role of Semaphorins as Major Regulatory Signals and Potential Therapeutic Targets in Cancer

(2012) Luca Tamagnone   CANCER CELL

Recurrent R-spondin fusions in colon cancer

(2012) Somasekar Seshagiri et al.   NATURE

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Comprehensive genomic characterization of squamous cell lung cancers

(2012)   NATURE

Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex

(2012) Bert J C Janssen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Plexins Are GTPase-Activating Proteins for Rap and Are Activated by Induced Dimerization

(2012) Y. Wang et al.   Science Signaling

Structural insights into semaphorins and their receptors

(2012) Christian Siebold et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Diverse roles for semaphorin−plexin signaling in the immune system

(2012) Hyota Takamatsu et al.   TRENDS IN IMMUNOLOGY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Semaphorin signaling in angiogenesis, lymphangiogenesis and cancer

(2011) Atsuko Sakurai et al.   CELL RESEARCH

Ca2+-dependent Monomer and Dimer Formation Switches CAPRI Protein between Ras GTPase-activating Protein (GAP) and RapGAP Activities

(2011) Yanfeng Dai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Frequent mutations of chromatin remodeling genes in transitional cell carcinoma of the bladder

(2011) Yaoting Gui et al.   NATURE GENETICS

Regulating Rap small G-proteins in time and space

(2011) Martijn Gloerich et al.   TRENDS IN CELL BIOLOGY

A Dual Binding Mode for RhoGTPases in Plexin Signalling

(2011) Christian H. Bell et al.   PLOS BIOLOGY

Structural Basis of Semaphorin-Plexin Recognition and Viral Mimicry from Sema7A and A39R Complexes with PlexinC1

(2010) Heli Liu et al.   CELL

Unravelling the mechanism of dual-specificity GAPs

(2010) Begoña Sot et al.   EMBO JOURNAL

Structural basis of semaphorin–plexin signalling

(2010) Bert J. C. Janssen et al.   NATURE

Structural basis for semaphorin signalling through the plexin receptor

(2010) Terukazu Nogi et al.   NATURE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Plexin-B1 is a GTPase activating protein for M-Ras, remodelling dendrite morphology

(2009) Yasuhiro Saito et al.   EMBO REPORTS

Structure and Function of the Intracellular Region of the Plexin-B1 Transmembrane Receptor

(2009) Yufeng Tong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Ability of GAP1IP4BP To Function as a Rap1 GTPase-Activating Protein (GAP) Requires Its Ras GAP-Related Domain and an Arginine Finger Rather than an Asparagine Thumb

(2009) S. Kupzig et al.   MOLECULAR AND CELLULAR BIOLOGY

Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration

(2009) H. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Rap–RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues

(2008) Andrea Scrima et al.   EMBO JOURNAL

The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction

(2008) Vladimir Pena et al.   EMBO REPORTS

Release of MICAL Autoinhibition by Semaphorin-Plexin Signaling Promotes Interaction with Collapsin Response Mediator Protein

(2008) E. F. Schmidt et al.   JOURNAL OF NEUROSCIENCE