The triggering receptor expressed on myeloid cells (TREM) in inflammatory bowel disease pathogenesis

TREM-1 Promotes Survival during Klebsiella pneumoniae Liver Abscess in Mice

(2014) Yi-Tsung Lin et al.   INFECTION AND IMMUNITY

Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1)-mediated Bcl-2 Induction Prolongs Macrophage Survival

(2014) Zhihong Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A New Triggering Receptor Expressed on Myeloid Cells (Trem) Family Member, Trem-Like 4, Binds to Dead Cells and Is a DNAX Activation Protein 12-Linked Marker for Subsets of Mouse Macrophages and Dendritic Cells

(2014) H. Hemmi et al.   JOURNAL OF IMMUNOLOGY

TREM-1 Deficiency Can Attenuate Disease Severity without Affecting Pathogen Clearance

(2014) Benjamin Weber et al.   PLoS Pathogens

Chronic hypoxia reprograms human immature dendritic cells by inducing a proinflammatory phenotype and TREM-1 expression

(2013) Daniele Pierobon et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Structure, expression pattern and biological activity of molecular complex TREM-2/DAP12

(2013) Agnieszka Paradowska-Gorycka et al.   HUMAN IMMUNOLOGY

TREM-1 inhibition attenuates inflammation and tumor within the colon

(2013) Jiangang Zhou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Prognostic Value and Therapeutic Potential of TREM-1 in Streptococcus pyogenes-Induced Sepsis

(2013) Sarah A. Horst et al.   Journal of Innate Immunity

Attenuated Inflammatory Response in Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Knock-Out Mice following Stroke

(2013) Matthias W. Sieber et al.   PLoS One

Alzheimer's disease risk alleles in TREM2 illuminate innate immunity in Alzheimer's disease

(2013) Todd E Golde et al.   Alzheimers Research & Therapy

TREM2, Frontotemporal Dementia–Like Disease, Nasu-Hakola Disease, and Alzheimer Dementia: A Chicken and Egg Problem?

(2013) Marino Muxfeldt Bianchin et al.   JAMA Neurology

Value of soluble TREM-1, procalcitonin, and C-reactive protein serum levels as biomarkers for detecting bacteremia among sepsis patients with new fever in intensive care units: a prospective cohort study

(2012) Longxiang Su et al.   BMC INFECTIOUS DISEASES

The Proinflammatory Myeloid Cell Receptor TREM-1 Controls Kupffer Cell Activation and Development of Hepatocellular Carcinoma

(2012) Juan Wu et al.   CANCER RESEARCH

Bacterial Sensor Triggering Receptor Expressed on Myeloid Cells-2 Regulates the Mucosal Inflammatory Response

(2012) Carmen Correale et al.   GASTROENTEROLOGY

Evaluation of TREM1 Gene Expression in Circulating Polymorphonuclear Leukocytes and Its Inverse Correlation with the Severity of Pathophysiological Conditions in Patients with Acute Bacterial Infections

(2012) Tsuneyuki Ubagai et al.   JAPANESE JOURNAL OF INFECTIOUS DISEASES

TLT-1s, Alternative Transcripts of Triggering Receptor Expressed on Myeloid Cell-like Transcript-1 (TLT-1), Inhibits the Triggering Receptor Expressed on Myeloid Cell-2 (TREM-2)-mediated Signaling Pathway during Osteoclastogenesis

(2012) Soo-Hyun Yoon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transepithelial migration of neutrophils into the lung requires TREM-1

(2012) Julia Klesney-Tait et al.   JOURNAL OF CLINICAL INVESTIGATION

Elevated levels of serum-soluble triggering receptor expressed on myeloid cells-1 in patients with IBD do not correlate with intestinal TREM-1 mRNA expression and endoscopic disease activity

(2012) Leslie Saurer et al.   Journal of Crohns & Colitis

Soluble Trem-like Transcript-1 Regulates Leukocyte Activation and Controls Microbial Sepsis

(2012) M. Derive et al.   JOURNAL OF IMMUNOLOGY

TREM-1: intracellular signaling pathways and interaction with pattern recognition receptors

(2012) R. J. W. Arts et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Expression and function of triggering receptor expressed on myeloid cells-1 (TREM-1) on canine neutrophils

(2011) Jingjing Li et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

CX3CR1 defines functionally distinct intestinal mononuclear phagocyte subsets which maintain their respective functions during homeostatic and inflammatory conditions

(2011) Benjamin Weber et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

TREM-2, triggering receptor expressed on myeloid cell-2, negatively regulates TLR responses in dendritic cells

(2011) Hiroaki Ito et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Induction of triggering receptor expressed on myeloid cells (TREM-1) in airway epithelial cells by 1,25(OH)2 vitamin D3

(2011) Isaura Rigo et al.   Innate Immunity

Relationships between genetic polymorphisms of triggering receptor expressed on myeloid cells-1 and inflammatory bowel diseases in the Korean population

(2011) Eun Suk Jung et al.   LIFE SCIENCES

Ulcerative Colitis

(2011) Silvio Danese et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inflammatory Bowel Disease

(2010) Arthur Kaser et al.   Annual Review of Immunology

Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo

(2010) M. C. Bosco et al.   BLOOD

Triggering receptor expressed on myeloid cells-1 (TREM-1) expression on gastric epithelium: implication for a role of TREM-1 in Helicobacter pylori infection

(2010) B. Schmaußer et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

TREM2- and DAP12-Dependent Activation of PI3K Requires DAP10 and Is Inhibited by SHIP1

(2010) Q. Peng et al.   Science Signaling

TREM and TREM-like receptors in inflammation and disease

(2009) Jill W Ford et al.   CURRENT OPINION IN IMMUNOLOGY

The Linker for Activation of B Cells (LAB)/Non-T Cell Activation Linker (NTAL) Regulates Triggering Receptor Expressed on Myeloid Cells (TREM)-2 Signaling and Macrophage Inflammatory Responses Independently of the Linker for Activation of T Cells

(2009) Gillian C. Whittaker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-10 Suppresses Calcium-Mediated Costimulation of Receptor Activator NF- B Signaling during Human Osteoclast Differentiation by Inhibiting TREM-2 Expression

(2009) K.-H. Park-Min et al.   JOURNAL OF IMMUNOLOGY

TREM-1 Activation Alters the Dynamics of Pulmonary IRAK-M Expression In Vivo and Improves Host Defense during Pneumococcal Pneumonia

(2009) H. Lagler et al.   JOURNAL OF IMMUNOLOGY

Signaling Pathways of the TREM-1- and TLR4-Mediated Neutrophil Oxidative Burst

(2009) Philipp Haselmayer et al.   Journal of Innate Immunity

Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation

(2008) Laura Piccio et al.   BRAIN

Correlation of Serum-Soluble Triggering Receptor Expressed on Myeloid Cells-1 with Clinical Disease Activity in Inflammatory Bowel Disease

(2008) Jae Jun Park et al.   DIGESTIVE DISEASES AND SCIENCES

Crosstalk between components of the innate immune system: promoting anti-microbial defenses and avoiding immunopathologies

(2008) Karine Crozat et al.   IMMUNOLOGICAL REVIEWS

The Innate Immune Response to Salmonella enterica Serovar Typhimurium by Macrophages Is Dependent on TREM2-DAP12

(2008) J. F. Charles et al.   INFECTION AND IMMUNITY

PDC-TREM, a plasmacytoid dendritic cell-specific receptor, is responsible for augmented production of type I interferon

(2008) H. Watarai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses

(2008) M. Hashiguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient colonic mucosal wound repair requires Trem2 signaling

(2008) H. Seno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TREM-1 Expression in Tumor-associated Macrophages and Clinical Outcome in Lung Cancer

(2007) Chao-Chi Ho et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Regulation of TREM expression in hepatic macrophages and endothelial cells during acute endotoxemia

(2007) Li C. Chen et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY