Modeling thrombin generation: plasma composition based approach

Elevated Prothrombin Promotes Venous, but Not Arterial, Thrombosis in Mice

(2013) Maria M. Aleman et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Towards kinetic modeling of genome-scale metabolic networks without sacrificing stoichiometric, thermodynamic and physiological constraints

(2013) Anirikh Chakrabarti et al.   Biotechnology Journal

Thrombin generation and whole blood viscoelastic assays in the management of hemophilia: current state of art and future perspectives

(2013) G. Young et al.   BLOOD

Depletion of systemic concentrations of coagulation factors in blood from patients with atherosclerotic vascular disease

(2013) Kathleen E. Brummel-Ziedins et al.   CORONARY ARTERY DISEASE

The use of microfluidics in hemostasis

(2013) Keith B. Neeves et al.   CURRENT OPINION IN HEMATOLOGY

Models for thrombin generation and risk of disease

(2013) K. Brummel-Ziedins   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

From Systems to Structure: Bridging Networks and Mechanism

(2013) James S. Fraser et al.   MOLECULAR CELL

From Principle to Practice: Bridging the Gap in Patient Profiling

(2013) Jonathan H. Foley et al.   PLoS One

Low endogenous thrombin potential in trained subjects

(2013) Christina Cimenti et al.   THROMBOSIS RESEARCH

HIV Replication Alters the Composition of Extrinsic Pathway Coagulation Factors and Increases Thrombin Generation

(2013) Jason V. Baker et al.   Journal of the American Heart Association

Modeling of human factor Va inactivation by activated protein C

(2012) Maria Bravo et al.   BMC Systems Biology

Whole-Blood Thrombin Generation Monitored with a Calibrated Automated Thrombogram-Based Assay

(2012) M. Ninivaggi et al.   CLINICAL CHEMISTRY

Defining the Boundaries of Normal Thrombin Generation: Investigations into Hemostasis

(2012) Christopher M. Danforth et al.   PLoS One

Factor Xa Generation by Computational Modeling: An Additional Discriminator to Thrombin Generation Evaluation

(2012) Kathleen E. Brummel-Ziedins et al.   PLoS One

The Prothrombotic Phenotypes in Familial Protein C Deficiency Are Differentiated by Computational Modeling of Thrombin Generation

(2012) Kathleen E. Brummel-Ziedins et al.   PLoS One

Global haemostasis assays, from bench to bedside

(2012) Mark van Geffen et al.   THROMBOSIS RESEARCH

Characteristics of Fibrin Formation and Clot Stability in Individuals with Congenital Type IIb Protein C Deficiency

(2012) J.H. Foley et al.   THROMBOSIS RESEARCH

Thrombin Generation in Hemorrhage Control and Vascular Occlusion

(2011) Kenneth G. Mann   CIRCULATION

Forecasting the Future of Cardiovascular Disease in the United States

(2011) Paul A. Heidenreich et al.   CIRCULATION

The influence of prophylactic factor VIII in severe haemophilia A

(2011) M. GISSEL et al.   HAEMOPHILIA

Obstetric Haemorrhage

(2011) A. B. MacLean   JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Activated protein C inhibitor for correction of thrombin generation in hemophilia A blood and plasma1

(2011) K. E. BRUMMEL-ZIEDINS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Kinetic modeling sheds light on the mode of action of recombinant factor VIIa on thrombin generation

(2011) Alexander Y. Mitrophanov et al.   THROMBOSIS RESEARCH

Thrombin generation in chronic obstructive pulmonary disease: Dependence on plasma factor composition

(2011) Anetta Undas et al.   THROMBOSIS RESEARCH

Surveillance for Deep Vein Thrombosis and Pulmonary Embolism

(2010) Gary E. Raskob et al.   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

Rivaroxaban: A New Oral Factor Xa Inhibitor

(2010) Elisabeth Perzborn et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Thrombin Flux and Wall Shear Rate Regulate Fibrin Fiber Deposition State during Polymerization under Flow

(2010) K.B. Neeves et al.   BIOPHYSICAL JOURNAL

Heart Disease and Stroke Statistics—2011 Update

(2010) Véronique L. Roger et al.   CIRCULATION

Hypercoagulable States

(2010) Julia A.M. Anderson et al.   CLINICS IN CHEST MEDICINE

Tests of global haemostasis and their applications in bleeding disorders

(2010) S. C. NAIR et al.   HAEMOPHILIA

Anticoagulation by factor Xa inhibitors

(2010) T. ORFEO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Thrombin generation in rheumatoid arthritis: Dependence on plasma factor composition

(2010) Anetta Undas et al.   THROMBOSIS AND HAEMOSTASIS

Plasma factor and inhibitor composition contributes to thrombin generation dynamics in patients with acute or previous cerebrovascular events

(2010) Matthew Gissel et al.   THROMBOSIS RESEARCH

Systems Biology of Coagulation Initiation: Kinetics of Thrombin Generation in Resting and Activated Human Blood

(2010) Manash S. Chatterjee et al.   PLoS Computational Biology

An Imbalance of Pro- vs Anti-Coagulation Factors in Plasma From Patients With Cirrhosis

(2009) Armando Tripodi et al.   GASTROENTEROLOGY

Thrombin generation and bleeding in haemophilia A

(2009) K. E. BRUMMEL-ZIEDINS et al.   HAEMOPHILIA

Empirical and theoretical phenotypic discrimination

(2009) K. E. BRUMMEL-ZIEDINS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Discordant fibrin formation in hemophilia

(2009) K. E. BRUMMEL-ZIEDINS et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The impact of uncertainty in a blood coagulation model

(2009) C. M. Danforth et al.   MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA

Endogenous thrombin potential, prothrombin fragment 1+2 and D-dimers during pregnancy

(2009) Stephanie Hierso et al.   THROMBOSIS AND HAEMOSTASIS

The effect of high circulating estradiol levels on thrombin generation during in vitro fertilization

(2009) Kathleen E. Brummel-Ziedins et al.   THROMBOSIS RESEARCH

Effects of Shear Rate on Propagation of Blood Clotting Determined Using Microfluidics and Numerical Simulations

(2008) Matthew K. Runyon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A model for the formation, growth, and lysis of clots in quiescent plasma. A comparison between the effects of antithrombin III deficiency and protein C deficiency

(2008) M. Anand et al.   JOURNAL OF THEORETICAL BIOLOGY

Elevated platelet and leukocyte response to oral bacteria in periodontitis

(2008) E. A. NICU et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Intraindividual thrombin generation measurement variability in healthy adults over a one year period

(2008) Yesim Dargaud et al.   THROMBOSIS RESEARCH