The tick-derived inhibitor Ixolaris prevents tissue factor signaling on tumor cells

Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice

(2012) A. M. Gil-Bernabe et al.   BLOOD

Inhibition of tissue factor by ixolaris reduces primary tumor growth and experimental metastasis in a murine model of melanoma

(2012) Andreia Da Silva de Oliveira et al.   THROMBOSIS RESEARCH

Tissue factor and cell signalling in cancer progression and thrombosis

(2011) W. RUF et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2–mediated heparin-binding EGF signaling in endothelial cells

(2011) Katrin J. Svensson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oncogenic epidermal growth factor receptor up-regulates multiple elements of the tissue factor signaling pathway in human glioma cells

(2010) N. Magnus et al.   BLOOD

Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development

(2010) F. Schaffner et al.   BLOOD

The Endothelial Protein C Receptor Supports Tissue Factor Ternary Coagulation Initiation Complex Signaling through Protease-activated Receptors

(2010) Jennifer Disse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Engineering of Substrate Selectivity for Tissue Factor·Factor VIIa Complex Signaling through Protease-activated Receptor 2

(2010) Katrine S. Larsen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ixolaris, a tissue factor inhibitor, blocks primary tumor growth and angiogenesis in a glioblastoma model

(2009) T. C. CARNEIRO-LOBO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Inhibition of tissue factor/protease-activated receptor-2 signaling limits proliferation, migration and invasion of malignant glioma cells

(2009) F. Gessler et al.   NEUROSCIENCE

Protease-Activated Receptor (PAR) 2, but not PAR1, Signaling Promotes the Development of Mammary Adenocarcinoma in Polyoma Middle T Mice

(2008) H. H. Versteeg et al.   CANCER RESEARCH

Blood Coagulation, Inflammation, and Malaria

(2008) Ivo M. B. Francischetti et al.   MICROCIRCULATION