Effect of flavonoids on learning, memory and neurocognitive performance: relevance and potential implications for Alzheimer's disease pathophysiology

The global prevalence of dementia: A systematic review and metaanalysis

(2013) Martin Prince et al.   Alzheimers & Dementia

Cocoa polyphenols enhance positive mood states but not cognitive performance: a randomized, placebo-controlled trial

(2013) Matthew P Pase et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Dietary Levels of Pure Flavonoids Improve Spatial Memory Performance and Increase Hippocampal Brain-Derived Neurotrophic Factor

(2013) Catarina Rendeiro et al.   PLoS One

Natural polyphenols against neurodegenerative disorders: Potentials and pitfalls

(2012) Azadeh Ebrahimi et al.   AGEING RESEARCH REVIEWS

2012 Alzheimer’s disease facts and figures

(2012)   Alzheimers & Dementia

Dietary intakes of berries and flavonoids in relation to cognitive decline

(2012) Elizabeth E. Devore et al.   ANNALS OF NEUROLOGY

Regulation of NF-κB activity in astrocytes: effects of flavonoids at dietary-relevant concentrations

(2012) Alison Spilsbury et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Neuroinflammation, Oxidative Stress and the Pathogenesis of Alzheimers Disease

(2012) Paula Agostinho et al.   CURRENT PHARMACEUTICAL DESIGN

Benefits in Cognitive Function, Blood Pressure, and Insulin Resistance Through Cocoa Flavanol Consumption in Elderly Subjects With Mild Cognitive Impairment

(2012) Giovambattista Desideri et al.   HYPERTENSION

Concord Grape Juice Supplementation and Neurocognitive Function in Human Aging

(2012) Robert Krikorian et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Tannic Acid Is a Natural β-Secretase Inhibitor That Prevents Cognitive Impairment and Mitigates Alzheimer-like Pathology in Transgenic Mice

(2012) Takashi Mori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fruit, vegetables and prevention of cognitive decline or dementia: A systematic review of cohort studies

(2012) M. Loef et al.   Journal of Nutrition Health & Aging

Relative impact of flavonoid composition, dose and structure on vascular function: A systematic review of randomised controlled trials of flavonoid-rich food products

(2012) Colin D. Kay et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Long-term soy isoflavone supplementation and cognition in women: A randomized, controlled trial

(2012) V. W. Henderson et al.   NEUROLOGY

Dietary Polyphenols as Modulators of Brain Functions: Biological Actions and Molecular Mechanisms Underpinning Their Beneficial Effects

(2012) David Vauzour   Oxidative Medicine and Cellular Longevity

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Flavonoid intake in relation to cognitive function in later life in the Lothian Birth Cohort 1936

(2011) Catherine Butchart et al.   BRITISH JOURNAL OF NUTRITION

Fruit and vegetable intake and cognitive decline in middle-aged men and women: the Doetinchem Cohort Study

(2011) Astrid C. J. Nooyens et al.   BRITISH JOURNAL OF NUTRITION

Systemic Inflammation Is Associated with MCI and Its Subtypes: The Sydney Memory and Aging Study

(2011) Julian N. Trollor et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Diet and Alzheimer’s disease risk factors or prevention: the current evidence

(2011) Vincenzo Solfrizzi et al.   Expert Review of Neurotherapeutics

Flavonoids, cognition, and dementia: Actions, mechanisms, and potential therapeutic utility for Alzheimer disease

(2011) Robert J. Williams et al.   FREE RADICAL BIOLOGY AND MEDICINE

Total and Specific Polyphenol Intakes in Midlife Are Associated with Cognitive Function Measured 13 Years Later

(2011) Emmanuelle Kesse-Guyot et al.   JOURNAL OF NUTRITION

Neuroinflammation: Modulation by flavonoids and mechanisms of action

(2011) Jeremy P.E. Spencer et al.   MOLECULAR ASPECTS OF MEDICINE

Alzheimer's Therapeutics: Translation of Preclinical Science to Clinical Drug Development

(2011) Alena V Savonenko et al.   NEUROPSYCHOPHARMACOLOGY

Consumption of cocoa flavanols results in an acute improvement in visual and cognitive functions

(2011) David T. Field et al.   PHYSIOLOGY & BEHAVIOR

Steady state visually evoked potential (SSVEP) topography changes associated with cocoa flavanol consumption

(2011) D.A. Camfield et al.   PHYSIOLOGY & BEHAVIOR

Influence of apolipoprotein E ɛ4 on rates of cognitive and functional decline in mild cognitive impairment

(2010) Danielle C. Whitehair et al.   Alzheimers & Dementia

Adherence to a Mediterranean-type dietary pattern and cognitive decline in a community population

(2010) C. C. Tangney et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Accruing evidence on benefits of adherence to the Mediterranean diet on health: an updated systematic review and meta-analysis

(2010) Francesco Sofi et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Food Combination and Alzheimer Disease Risk

(2010) Yian Gu   ARCHIVES OF NEUROLOGY

Genetic evidence for the involvement of lipid metabolism in Alzheimer's disease

(2010) Lesley Jones et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Fruit polyphenols, immunity and inflammation

(2010) Javier González-Gallego et al.   BRITISH JOURNAL OF NUTRITION

The flavonoid baicalein promotes NMDA receptor-dependent long-term potentiation and enhances memory

(2010) Wei Wang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Blueberry Supplementation Improves Memory in Older Adults†

(2010) Robert Krikorian et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Inhibition of I B Kinase-  Protects Dopamine Neurons Against Lipopolysaccharide-Induced Neurotoxicity

(2010) F. Zhang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Inhibition of nitric oxide production by quercetin in endotoxin/cytokine-stimulated microglia

(2010) Tsung-Kuei Kao et al.   LIFE SCIENCES

Natural products as a source of Alzheimer's drug leads

(2010) Philip Williams et al.   NATURAL PRODUCT REPORTS

Serum C-reactive protein is linked to cerebral microstructural integrity and cognitive function

(2010) H. Wersching et al.   NEUROLOGY

Rate of progression of mild cognitive impairment to dementia - meta-analysis of 41 robust inception cohort studies

(2009) A. J. Mitchell et al.   ACTA PSYCHIATRICA SCANDINAVICA

Elevated C-reactive protein levels are associated with prevalent dementia in the oldest-old

(2009) B. Adar Kravitz et al.   Alzheimers & Dementia

Association of C-reactive protein with mild cognitive impairment

(2009) Rosebud O. Roberts et al.   Alzheimers & Dementia

Role of oxidative stress and AT1 receptors in cerebral vascular dysfunction with aging

(2009) Mary L. Modrick et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Flavonoids and cognition: The molecular mechanisms underlying their behavioural effects

(2009) Jeremy P.E. Spencer et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The citrus flavanone naringenin inhibits inflammatory signalling in glial cells and protects against neuroinflammatory injury

(2009) Katerina Vafeiadou et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Effects of Family History and Apolipoprotein E ε4 Status on Cognitive Decline in the Absence of Alzheimer Dementia

(2009) Kathleen M. Hayden   ARCHIVES OF NEUROLOGY

Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment

(2009) Robert Krikorian et al.   BRITISH JOURNAL OF NUTRITION

Inflammatory Disease Processes and Interactions with Nutrition

(2009) P. C. Calder et al.   BRITISH JOURNAL OF NUTRITION

The impact of flavonoids on memory: physiological and molecular considerations

(2009) Jeremy P. E. Spencer   CHEMICAL SOCIETY REVIEWS

Impact of diet on adult hippocampal neurogenesis

(2009) Doris Stangl et al.   Genes and Nutrition

Consumption of cocoa flavanols results in acute improvements in mood and cognitive performance during sustained mental effort

(2009) Andrew B Scholey et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Dietary phenolics: chemistry, bioavailability and effects on health

(2009) Alan Crozier et al.   NATURAL PRODUCT REPORTS

Long-term administration of green tea catechins prevents age-related spatial learning and memory decline in C57BL/6 J mice by regulating hippocampal cyclic amp-response element binding protein signaling cascade

(2009) Q. Li et al.   NEUROSCIENCE

Long-term green tea catechin administration prevents spatial learning and memory impairment in senescence-accelerated mouse prone-8 mice by decreasing Aβ1-42 oligomers and upregulating synaptic plasticity–related proteins in the hippocampus

(2009) Q. Li et al.   NEUROSCIENCE

Transcription Factors in Long-Term Memory and Synaptic Plasticity

(2009) Cristina M. Alberini   PHYSIOLOGICAL REVIEWS

Aging and Replicative Senescence Have Related Effects on Human Stem and Progenitor Cells

(2009) Wolfgang Wagner et al.   PLoS One

No acute effects of grape juice on appetite, implicit memory and mood

(2009) Sara J. Hendrickson et al.   Food & Nutrition Research

Flavonols and flavones as BACE-1 inhibitors: Structure–activity relationship in cell-free, cell-based and in silico studies reveal novel pharmacophore features

(2008) Yoshiari Shimmyo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Chlorogenic Acid and Its Metabolitem-Coumaric Acid Evoke Neurite Outgrowth in Hippocampal Neuronal Cells

(2008) Hideyuki ITO et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Green tea epigallocatechin-3-gallate (EGCG) reduces β-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice

(2008) Kavon Rezai-Zadeh et al.   BRAIN RESEARCH

Mechanisms and Functional Implications of Adult Neurogenesis

(2008) Chunmei Zhao et al.   CELL

Blueberry-induced changes in spatial working memory correlate with changes in hippocampal CREB phosphorylation and brain-derived neurotrophic factor (BDNF) levels

(2008) Claire M. Williams et al.   FREE RADICAL BIOLOGY AND MEDICINE

The neuroprotective potential of flavonoids: a multiplicity of effects

(2008) David Vauzour et al.   Genes and Nutrition

Effects of Grape Seed-derived Polyphenols on Amyloid β-Protein Self-assembly and Cytotoxicity

(2008) Kenjiro Ono et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intake of Flavonoid-Rich Wine, Tea, and Chocolate by Elderly Men and Women Is Associated with Better Cognitive Test Performance

(2008) Eha Nurk et al.   JOURNAL OF NUTRITION

Nobiletin, a Citrus Flavonoid, Improves Memory Impairment and A  Pathology in a Transgenic Mouse Model of Alzheimer's Disease

(2008) H. Onozuka et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Sustained Benefits in Vascular Function Through Flavanol-Containing Cocoa in Medicated Diabetic Patients

(2008) Jan Balzer et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers

(2008) Dagmar E Ehrnhoefer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

In vitro and ex vivo anti-inflammatory activity of quercetin in healthy volunteers

(2008) Agnes W. Boots et al.   NUTRITION

Targeting multiple Alzheimer’s disease etiologies with multimodal neuroprotective and neurorestorative iron chelators

(2007) Tamar Amit et al.   FASEB JOURNAL

Resveratrol and quercetin, two natural polyphenols, reduce apoptotic neuronal cell death induced by neuroinflammation

(2007) Genevieve Bureau et al.   JOURNAL OF NEUROSCIENCE RESEARCH