Combining Targeted Agents With Modern Radiotherapy in Soft Tissue Sarcomas
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Combining Targeted Agents With Modern Radiotherapy in Soft Tissue Sarcomas
Authors
Keywords
-
Journal
JNCI-Journal of the National Cancer Institute
Volume 106, Issue 11, Pages dju329-dju329
Publisher
Oxford University Press (OUP)
Online
2014-10-19
DOI
10.1093/jnci/dju329
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- In Vivo Antitumor and Antimetastatic Activity of Sunitinib in Preclinical Neuroblastoma Mouse Model
- (2015) Libo Zhang et al. NEOPLASIA
- The Dual PI3K/mTOR Inhibitor NVP-BEZ235 Is a Potent Inhibitor of ATM- and DNA-PKCs-Mediated DNA Damage Responses
- (2015) Bipasha Mukherjee et al. NEOPLASIA
- Phase I Trial of Neoadjuvant Conformal Radiotherapy Plus Sorafenib for Patients with Locally Advanced Soft Tissue Sarcoma of the Extremity
- (2014) Robert J. Canter et al. ANNALS OF SURGICAL ONCOLOGY
- Systemic treatment of soft-tissue sarcoma—gold standard and novel therapies
- (2014) Mark Linch et al. Nature Reviews Clinical Oncology
- Combined management of retroperitoneal sarcoma with dose intensification radiotherapy and resection: Long-term results of a prospective trial
- (2014) Myles J.F. Smith et al. RADIOTHERAPY AND ONCOLOGY
- Inflammatory Myofibroblastic Tumors Harbor Multiple Potentially Actionable Kinase Fusions
- (2014) C. M. Lovly et al. Cancer Discovery
- Sarcoma Diagnosis in the Age of Molecular Pathology
- (2013) Elizabeth G. Demicco ADVANCES IN ANATOMIC PATHOLOGY
- Early onset recall pneumonitis during targeted therapy with sunitinib
- (2013) Takeshi Yuasa et al. BMC CANCER
- Phase 2 study of preoperative image-guided intensity-modulated radiation therapy to reduce wound and combined modality morbidities in lower extremity soft tissue sarcoma
- (2013) Brian O'Sullivan et al. CANCER
- Radiotherapy of Human Sarcoma Promotes an Intratumoral Immune Effector Signature
- (2013) A. Sharma et al. CLINICAL CANCER RESEARCH
- Phase I Trial of Preoperative Chemoradiation plus Sorafenib for High-Risk Extremity Soft Tissue Sarcomas with Dynamic Contrast-Enhanced MRI Correlates
- (2013) J. M. Meyer et al. CLINICAL CANCER RESEARCH
- Pazopanib, a new therapy for metastatic soft tissue sarcoma
- (2013) Jaap Verweij et al. EXPERT OPINION ON PHARMACOTHERAPY
- Sunitinib Plus Androgen Deprivation and Radiation Therapy for Patients With Localized High-Risk Prostate Cancer: Results From a Multi-institutional Phase 1 Study
- (2013) Paul G. Corn et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Fluorouracil, Leucovorin, and Irinotecan Plus Either Sunitinib or Placebo in Metastatic Colorectal Cancer: A Randomized, Phase III Trial
- (2013) Alfredo Carrato et al. JOURNAL OF CLINICAL ONCOLOGY
- Designing Transformative Clinical Trials in the Cancer Genome Era
- (2013) Stefan Sleijfer et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase II Trial of the CDK4 Inhibitor PD0332991 in Patients With Advanced CDK4-Amplified Well-Differentiated or Dedifferentiated Liposarcoma
- (2013) Mark A. Dickson et al. JOURNAL OF CLINICAL ONCOLOGY
- Opportunities and Challenges in the Era of Molecularly Targeted Agents and Radiation Therapy
- (2013) Steven H. Lin et al. JNCI-Journal of the National Cancer Institute
- Combining Radiotherapy and Cancer Immunotherapy: A Paradigm Shift
- (2013) Silvia C. Formenti et al. JNCI-Journal of the National Cancer Institute
- ALK Inhibitor PF02341066 (Crizotinib) Increases Sensitivity to Radiation in Non-Small Cell Lung Cancer Expressing EML4-ALK
- (2013) Y. Sun et al. MOLECULAR CANCER THERAPEUTICS
- Combining PARP-1 Inhibition and Radiation in Ewing Sarcoma Results in Lethal DNA Damage
- (2013) Hae-June Lee et al. MOLECULAR CANCER THERAPEUTICS
- Strategies for optimizing the response of cancer and normal tissues to radiation
- (2013) Everett J. Moding et al. NATURE REVIEWS DRUG DISCOVERY
- Pazopanib versus Sunitinib in Metastatic Renal-Cell Carcinoma
- (2013) Robert J. Motzer et al. NEW ENGLAND JOURNAL OF MEDICINE
- PI3K Inhibition Enhances Doxorubicin-Induced Apoptosis in Sarcoma Cells
- (2013) Diana Marklein et al. PLoS One
- Tumor Infiltrating PD1-Positive Lymphocytes and the Expression of PD-L1 Predict Poor Prognosis of Soft Tissue Sarcomas
- (2013) Jung Ryul Kim et al. PLoS One
- Postoperative complications following neoadjuvant bevacizumab treatment for advanced colorectal cancer
- (2013) Yuichiro Yoshioka et al. SURGERY TODAY
- Silencing CDK4 radiosensitizes breast cancer cells by promoting apoptosis
- (2013) Katie R Hagen et al. Cell Division
- New Therapeutic Targets in Soft Tissue Sarcoma
- (2012) Elizabeth G. Demicco et al. ADVANCES IN ANATOMIC PATHOLOGY
- Phase II prospective study with sorafenib in advanced soft tissue sarcomas after anthracycline-based therapy
- (2012) A. Santoro et al. ANNALS OF ONCOLOGY
- An open-label, multicenter, phase II study of bevacizumab for the treatment of angiosarcoma and epithelioid hemangioendotheliomas
- (2012) M. Agulnik et al. ANNALS OF ONCOLOGY
- Deconstruction of the SS18-SSX Fusion Oncoprotein Complex: Insights into Disease Etiology and Therapeutics
- (2012) Le Su et al. CANCER CELL
- PARP-1 Inhibition as a Targeted Strategy to Treat Ewing's Sarcoma
- (2012) J. C. Brenner et al. CANCER RESEARCH
- First-Line Treatment of Advanced Breast Cancer With Sunitinib in Combination With Docetaxel Versus Docetaxel Alone: Results of a Prospective, Randomized Phase III Study
- (2012) Jonas Bergh et al. JOURNAL OF CLINICAL ONCOLOGY
- Sunitinib Plus Erlotinib Versus Placebo Plus Erlotinib in Patients With Previously Treated Advanced Non–Small-Cell Lung Cancer: A Phase III Trial
- (2012) Giorgio V. Scagliotti et al. JOURNAL OF CLINICAL ONCOLOGY
- A novel multi-kinase inhibitor pazopanib suppresses growth of synovial sarcoma cells through inhibition of the PI3K-AKT pathway
- (2012) Seiichi Hosaka et al. JOURNAL OF ORTHOPAEDIC RESEARCH
- NCI–RTOG Translational Program Strategic Guidelines for the Early-Stage Development of Radiosensitizers
- (2012) Yaacov Richard Lawrence et al. JNCI-Journal of the National Cancer Institute
- Pazopanib and the treatment palette for soft-tissue sarcoma
- (2012) Vivien HC Bramwell LANCET
- Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial
- (2012) Winette TA van der Graaf et al. LANCET
- Effect of the MDM2 antagonist RG7112 on the P53 pathway in patients with MDM2-amplified, well-differentiated or dedifferentiated liposarcoma: an exploratory proof-of-mechanism study
- (2012) Isabelle Ray-Coquard et al. LANCET ONCOLOGY
- A phase II study of sunitinib in patients with relapsed or refractory small cell lung cancer
- (2012) Ji-Youn Han et al. LUNG CANCER
- A retrospective study of SBRT of metastases in patients with primary sarcoma
- (2012) Christina Linder Stragliotto et al. MEDICAL ONCOLOGY
- Akt Promotes Post-Irradiation Survival of Human Tumor Cells through Initiation, Progression, and Termination of DNA-PKcs-Dependent DNA Double-Strand Break Repair
- (2012) M. Toulany et al. MOLECULAR CANCER RESEARCH
- Systematic identification of genomic markers of drug sensitivity in cancer cells
- (2012) Mathew J. Garnett et al. NATURE
- Concise Drug Review: Pazopanib and Axitinib
- (2012) R. M. J. M. van Geel et al. ONCOLOGIST
- Initial testing of the MDM2 inhibitor RG7112 by the pediatric preclinical testing program
- (2012) Hernan Carol et al. PEDIATRIC BLOOD & CANCER
- Improving Outcomes for Retroperitoneal Sarcomas: A Work in Progress
- (2012) Carol J. Swallow et al. Surgical Oncology Clinics of North America
- Activation of the AKT/cyclin D1/Cdk4 survival signaling pathway in radioresistant cancer stem cells
- (2012) T Shimura et al. Oncogenesis
- Hemorrhagic complications in a phase II study of sunitinib in patients of nasopharyngeal carcinoma who has previously received high-dose radiation
- (2011) E. P. Hui et al. ANNALS OF ONCOLOGY
- The safety and efficacy of sunitinib before planned nephrectomy in metastatic clear cell renal cancer
- (2011) T. Powles et al. ANNALS OF ONCOLOGY
- A phase 1b trial of the combination of the antiangiogenic agent sunitinib and radiation therapy for patients with primary and metastatic central nervous system malignancies
- (2011) Evan J. Wuthrick et al. CANCER
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Phase I and Pharmacokinetic Study of Sunitinib in Pediatric Patients with Refractory Solid Tumors: A Children's Oncology Group Study
- (2011) S. G. DuBois et al. CLINICAL CANCER RESEARCH
- Phase I, Dose-Escalation Trial of the Oral Cyclin-Dependent Kinase 4/6 Inhibitor PD 0332991, Administered Using a 21-Day Schedule in Patients with Advanced Cancer
- (2011) K. T. Flaherty et al. CLINICAL CANCER RESEARCH
- Clinical and molecular approaches to well differentiated and dedifferentiated liposarcoma
- (2011) Aimee M Crago et al. CURRENT OPINION IN ONCOLOGY
- Pharmacologic Activation of p53 by Small-Molecule MDM2 Antagonists
- (2011) Hong Shen et al. CURRENT PHARMACEUTICAL DESIGN
- Targeting the AKT/GSK3β/Cyclin D1/Cdk4 Survival Signaling Pathway for Eradication of Tumor Radioresistance Acquired by Fractionated Radiotherapy
- (2011) Tsutomu Shimura et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Combination of External Beam Radiotherapy (EBRT) With Intratumoral Injection of Dendritic Cells as Neo-Adjuvant Treatment of High-Risk Soft Tissue Sarcoma Patients
- (2011) Steven E. Finkelstein et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Stereotactic Body Radiotherapy for Pulmonary Metastases From Soft-Tissue Sarcomas: Excellent Local Lesion Control and Improved Patient Survival
- (2011) Sughosh Dhakal et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Aberrant AKT activation drives well-differentiated liposarcoma
- (2011) A. Gutierrez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Radioresistance of human glioma spheroids and expression of HSP70, p53 and EGFr
- (2011) Carlos A Fedrigo et al. Radiation Oncology
- Effect of adjuvant chemotherapy on survival in FNCLCC grade 3 soft tissue sarcomas: a multivariate analysis of the French Sarcoma Group Database
- (2010) A. Italiano et al. ANNALS OF ONCOLOGY
- Does Neoadjuvant Bevacizumab Increase Surgical Complications in Breast Surgery?
- (2010) M. Golshan et al. ANNALS OF SURGICAL ONCOLOGY
- Phase III randomized trial of sunitinib versus capecitabine in patients with previously treated HER2-negative advanced breast cancer
- (2010) Carlos H. Barrios et al. BREAST CANCER RESEARCH AND TREATMENT
- Phase II study of sunitinib malate, a multitargeted tyrosine kinase inhibitor in patients with relapsed or refractory soft tissue sarcomas. Focus on three prevalent histologies: Leiomyosarcoma, liposarcoma and malignant fibrous histiocytoma
- (2010) S. Tariq Mahmood et al. INTERNATIONAL JOURNAL OF CANCER
- Phosphoinositide-3-Kinase Inhibition Enhances Radiosensitization of Cervical Cancer In Vivo
- (2010) Yi Liu et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Effect of rapamycin, an mTOR inhibitor, on radiation sensitivity of lung cancer cells having different p53 gene status
- (2010) Nagata INTERNATIONAL JOURNAL OF ONCOLOGY
- Enhancement of Radiation Response in Osteosarcoma and Rhabomyosarcoma Cell Lines by Histone Deacetylase Inhibition
- (2010) Claudia Blattmann et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Angiogenic Blockade and Radiotherapy in Hepatocellular Carcinoma
- (2010) Kwan-Hwa Chi et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Phase II Study of Neoadjuvant Bevacizumab and Radiotherapy for Resectable Soft Tissue Sarcomas
- (2010) Sam S. Yoon et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Neoadjuvant Bevacizumab, Oxaliplatin, 5-Fluorouracil, and Radiation for Rectal Cancer
- (2010) Tom Dipetrillo et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Stereotactic Body Radiation Therapy for Inoperable Early Stage Lung Cancer
- (2010) Robert Timmerman JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Sunitinib-Induced Pseudoprogression After Whole-Brain Radiotherapy for Metastatic Renal Cell Carcinoma
- (2010) Paul J. Kelly et al. JOURNAL OF CLINICAL ONCOLOGY
- Neoadjuvant Clinical Trial With Sorafenib for Patients With Stage II or Higher Renal Cell Carcinoma
- (2010) C. Lance Cowey et al. JOURNAL OF CLINICAL ONCOLOGY
- Bevacizumab-induced tumor vessel remodeling in rhabdomyosarcoma xenografts increases the effectiveness of adjuvant ionizing radiation
- (2010) Adrianne L. Myers et al. JOURNAL OF PEDIATRIC SURGERY
- Prospective Clinical Trial of Preoperative Sunitinib in Patients With Renal Cell Carcinoma
- (2010) Nicholas J. Hellenthal et al. JOURNAL OF UROLOGY
- Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy
- (2010) Jordi Barretina et al. NATURE GENETICS
- Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity
- (2010) Frédéric Chibon et al. NATURE MEDICINE
- Crizotinib inALK-Rearranged Inflammatory Myofibroblastic Tumor
- (2010) James E. Butrynski et al. NEW ENGLAND JOURNAL OF MEDICINE
- Feasibility and effects of high-dose hypofractionated radiation therapy and simultaneous multi-kinase inhibition with sunitinib in progressive metastatic renal cell cancer
- (2010) Michael Staehler et al. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
- Radiosensitivity translates into excellent local control in extremity myxoid liposarcoma
- (2009) Peter W. M. Chung et al. CANCER
- Phase 1 study of concurrent sunitinib and image-guided radiotherapy followed by maintenance sunitinib for patients with oligometastases
- (2009) Johnny Kao et al. CANCER
- A Three-Gene Signature for Outcome in Soft Tissue Sarcoma
- (2009) A.-C. Hoffmann et al. CLINICAL CANCER RESEARCH
- Efficacy of Sunitinib and Radiotherapy in Genetically Engineered Mouse Model of Soft-Tissue Sarcoma
- (2009) Sam S. Yoon et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Stereotactic Body Radiation Therapy for Early-Stage Non–Small-Cell Lung Carcinoma: Four-Year Results of a Prospective Phase II Study
- (2009) Achilles J. Fakiris et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Intensity-Modulated Radiotherapy–Based Stereotactic Body Radiotherapy for Medically Inoperable Early-Stage Lung Cancer: Excellent Local Control
- (2009) Gregory M.M. Videtic et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Multicenter Phase II Trial of Sunitinib in the Treatment of Nongastrointestinal Stromal Tumor Sarcomas
- (2009) Suzanne George et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase II Study of Sorafenib in Patients With Metastatic or Recurrent Sarcomas
- (2009) Robert G. Maki et al. JOURNAL OF CLINICAL ONCOLOGY
- Pazopanib, a Multikinase Angiogenesis Inhibitor, in Patients With Relapsed or Refractory Advanced Soft Tissue Sarcoma: A Phase II Study From the European Organisation for Research and Treatment of Cancer–Soft Tissue and Bone Sarcoma Group (EORTC Study 62043)
- (2009) Stefan Sleijfer et al. JOURNAL OF CLINICAL ONCOLOGY
- Can MDM2 and CDK4 make the diagnosis of well differentiated/dedifferentiated liposarcoma? An immunohistochemical study on 129 soft tissue tumours
- (2009) P B Aleixo et al. JOURNAL OF CLINICAL PATHOLOGY
- Potent and Orally Active Small-Molecule Inhibitors of the MDM2−p53 Interaction
- (2009) Shanghai Yu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Radiation-induced Akt activation modulates radioresistance in human glioblastoma cells
- (2009) Hui-Fang Li et al. Radiation Oncology
- Why Do Patients with Low-Grade Soft Tissue Sarcoma Die?
- (2008) Robert J. Canter et al. ANNALS OF SURGICAL ONCOLOGY
- A systematic meta-analysis of randomized controlled trials of adjuvant chemotherapy for localized resectable soft-tissue sarcoma
- (2008) Nabeel Pervaiz et al. CANCER
- Meta-analysis of ifosfamide-based combination chemotherapy in advanced soft tissue sarcoma
- (2008) Shailendra Verma et al. CANCER TREATMENT REVIEWS
- Preoperative Bevacizumab Does Not Significantly Increase Postoperative Complication Rates in Patients Undergoing Hepatic Surgery for Colorectal Cancer Liver Metastases
- (2008) Susan B. Kesmodel et al. JOURNAL OF CLINICAL ONCOLOGY
- Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial
- (2008) Ann-Lii Cheng et al. LANCET ONCOLOGY
- Sorafenib in Advanced Hepatocellular Carcinoma
- (2008) Josep M. Llovet et al. NEW ENGLAND JOURNAL OF MEDICINE
- Initial testing (stage 1) of sunitinib by the pediatric preclinical testing program
- (2008) John M. Maris et al. PEDIATRIC BLOOD & CANCER
- Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition
- (2008) S. Shangary et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Progress in Childhood Cancer: 50 Years of Research Collaboration, a Report From the Children's Oncology Group
- (2008) Maura O'Leary et al. SEMINARS IN ONCOLOGY
- Preoperative radiotherapy and bevacizumab for angiosarcoma of the head and neck: Two case studies
- (2007) Bridget F. Koontz et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More