Hexon Modification to Improve the Activity of Oncolytic Adenovirus Vectors against Neoplastic and Stromal Cells in Pancreatic Cancer
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Hexon Modification to Improve the Activity of Oncolytic Adenovirus Vectors against Neoplastic and Stromal Cells in Pancreatic Cancer
Authors
Keywords
Pancreatic cancer, Infectious disease control, DNA isolation, Hepatocytes, Vector-borne diseases, Viral replication, Flow cytometry, Viral vectors
Journal
PLoS One
Volume 10, Issue 2, Pages e0117254
Publisher
Public Library of Science (PLoS)
Online
2015-02-19
DOI
10.1371/journal.pone.0117254
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Traceless Bioresponsive Shielding of Adenovirus Hexon with HPMA Copolymers Maintains Transduction Capacity In Vitro and In Vivo
- (2014) Jan-Michael Prill et al. PLoS One
- SR-A and SREC-I Are Kupffer and Endothelial Cell Receptors for Helper-dependent Adenoviral Vectors
- (2013) Pasquale Piccolo et al. MOLECULAR THERAPY
- Coagulation factor X shields adenovirus type 5 from attack by natural antibodies and complement
- (2013) Zhili Xu et al. NATURE MEDICINE
- Cancers with increasing incidence trends in the United States: 1999 through 2008
- (2012) Edgar P. Simard et al. CA-A CANCER JOURNAL FOR CLINICIANS
- CRIg mediates early Kupffer cell responses to adenovirus
- (2012) J. Q. He et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Identification of Adenovirus Serotype 5 Hexon Regions That Interact with Scavenger Receptors
- (2011) R. Khare et al. JOURNAL OF VIROLOGY
- Generation of a Kupffer Cell-evading Adenovirus for Systemic and Liver-directed Gene Transfer
- (2011) Reeti Khare et al. MOLECULAR THERAPY
- Rapid and Efficient Clearance of Blood-borne Virus by Liver Sinusoidal Endothelium
- (2011) Latha P. Ganesan et al. PLoS Pathogens
- Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors
- (2010) R. Alba et al. BLOOD
- Identification of c-FLIPL and c-FLIPS as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells
- (2010) C. Haag et al. GUT
- Substitution of Adenovirus Serotype 3 Hexon onto a Serotype 5 Oncolytic Adenovirus Reduces Factor X Binding, Decreases Liver Tropism, and Improves Antitumor Efficacy
- (2010) J. J. Short et al. MOLECULAR CANCER THERAPEUTICS
- Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer
- (2009) R. Alba et al. BLOOD
- Efficient delivery of angiostatin K1-5 into tumors following insertion of an NGR peptide into adenovirus capsid
- (2009) B Jullienne et al. GENE THERAPY
- Expanded Anticancer Therapeutic Window of Hexon-modified Oncolytic Adenovirus
- (2009) Elena V Shashkova et al. MOLECULAR THERAPY
- Cancer Statistics, 2008
- (2008) A. Jemal et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression
- (2008) R. F. Hwang et al. CANCER RESEARCH
- Adenovirus Serotype 5 Hexon Mediates Liver Gene Transfer
- (2008) Simon N. Waddington et al. CELL
- Clearance of Adenovirus by Kupffer Cells Is Mediated by Scavenger Receptors, Natural Antibodies, and Complement
- (2008) Z. Xu et al. JOURNAL OF VIROLOGY
- Substitution of Hexon Hypervariable Region 5 of Adenovirus Serotype 5 Abrogates Blood Factor Binding and Limits Gene Transfer to Liver
- (2008) Frédéric Vigant et al. MOLECULAR THERAPY
- Adenovirus serotype 5 hexon is critical for virus infection of hepatocytes in vivo
- (2008) O. Kalyuzhniy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fully Detargeted Polyethylene Glycol-coated Adenovirus Vectors Are Potent Genetic Vaccines and Escape from Pre-existing Anti-adenovirus Antibodies
- (2007) Andreas Wortmann et al. MOLECULAR THERAPY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More