Hexon Modification to Improve the Activity of Oncolytic Adenovirus Vectors against Neoplastic and Stromal Cells in Pancreatic Cancer

Traceless Bioresponsive Shielding of Adenovirus Hexon with HPMA Copolymers Maintains Transduction Capacity In Vitro and In Vivo

(2014) Jan-Michael Prill et al.   PLoS One

SR-A and SREC-I Are Kupffer and Endothelial Cell Receptors for Helper-dependent Adenoviral Vectors

(2013) Pasquale Piccolo et al.   MOLECULAR THERAPY

Coagulation factor X shields adenovirus type 5 from attack by natural antibodies and complement

(2013) Zhili Xu et al.   NATURE MEDICINE

Cancers with increasing incidence trends in the United States: 1999 through 2008

(2012) Edgar P. Simard et al.   CA-A CANCER JOURNAL FOR CLINICIANS

CRIg mediates early Kupffer cell responses to adenovirus

(2012) J. Q. He et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Identification of Adenovirus Serotype 5 Hexon Regions That Interact with Scavenger Receptors

(2011) R. Khare et al.   JOURNAL OF VIROLOGY

Generation of a Kupffer Cell-evading Adenovirus for Systemic and Liver-directed Gene Transfer

(2011) Reeti Khare et al.   MOLECULAR THERAPY

Rapid and Efficient Clearance of Blood-borne Virus by Liver Sinusoidal Endothelium

(2011) Latha P. Ganesan et al.   PLoS Pathogens

Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors

(2010) R. Alba et al.   BLOOD

Identification of c-FLIPL and c-FLIPS as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells

(2010) C. Haag et al.   GUT

Substitution of Adenovirus Serotype 3 Hexon onto a Serotype 5 Oncolytic Adenovirus Reduces Factor X Binding, Decreases Liver Tropism, and Improves Antitumor Efficacy

(2010) J. J. Short et al.   MOLECULAR CANCER THERAPEUTICS

Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer

(2009) R. Alba et al.   BLOOD

Efficient delivery of angiostatin K1-5 into tumors following insertion of an NGR peptide into adenovirus capsid

(2009) B Jullienne et al.   GENE THERAPY

Expanded Anticancer Therapeutic Window of Hexon-modified Oncolytic Adenovirus

(2009) Elena V Shashkova et al.   MOLECULAR THERAPY

Cancer Statistics, 2008

(2008) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cancer-Associated Stromal Fibroblasts Promote Pancreatic Tumor Progression

(2008) R. F. Hwang et al.   CANCER RESEARCH

Adenovirus Serotype 5 Hexon Mediates Liver Gene Transfer

(2008) Simon N. Waddington et al.   CELL

Clearance of Adenovirus by Kupffer Cells Is Mediated by Scavenger Receptors, Natural Antibodies, and Complement

(2008) Z. Xu et al.   JOURNAL OF VIROLOGY

Substitution of Hexon Hypervariable Region 5 of Adenovirus Serotype 5 Abrogates Blood Factor Binding and Limits Gene Transfer to Liver

(2008) Frédéric Vigant et al.   MOLECULAR THERAPY

Adenovirus serotype 5 hexon is critical for virus infection of hepatocytes in vivo

(2008) O. Kalyuzhniy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fully Detargeted Polyethylene Glycol-coated Adenovirus Vectors Are Potent Genetic Vaccines and Escape from Pre-existing Anti-adenovirus Antibodies

(2007) Andreas Wortmann et al.   MOLECULAR THERAPY