Differential Contribution of TRPA1, TRPV4 and TRPM8 to Colonic Nociception in Mice

TRPM8 has a key role in experimental colitis-induced visceral hyperalgesia in mice

(2014) T. Hosoya et al.   NEUROGASTROENTEROLOGY AND MOTILITY

TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins

(2014) Victor Meseguer et al.   Nature Communications

TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain

(2013) Boyi Liu et al.   PAIN

TRPM8 activation attenuates inflammatory responses in mouse models of colitis

(2013) R. Ramachandran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Piezo proteins are pore-forming subunits of mechanically activated channels

(2012) Bertrand Coste et al.   NATURE

The dilated TRPA1 channel pore state is blocked by amiloride and analogues

(2011) Tue G. Banke   BRAIN RESEARCH

TRPA1 and Substance P Mediate Colitis in Mice

(2011) Matthias A. Engel et al.   GASTROENTEROLOGY

Transient Receptor Potential Ankyrin 1 Is Expressed by Inhibitory Motoneurons of the Mouse Intestine

(2011) Daniel P. Poole et al.   GASTROENTEROLOGY

A novel role for TRPM8 in visceral afferent function

(2011) Andrea M. Harrington et al.   PAIN

Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system

(2011) Peter Holzer   PHARMACOLOGY & THERAPEUTICS

Transient Receptor Potential Vanilloid 4 Activated Inflammatory Signals by Intestinal Epithelial Cells and Colitis in Mice

(2010) Emilie D'Aldebert et al.   GASTROENTEROLOGY

Wild-type and Brachyolmia-causing Mutant TRPV4 Channels Respond Directly to Stretch Force

(2010) Stephen Loukin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anatomical registration and three-dimensional visualization of low and high-resolution pan-colonic manometry recordings

(2010) J. B. Davidson et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Transient receptor potential ankyrin-1 has a major role in mediating visceral pain in mice

(2009) Fiore Cattaruzza et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Molecular basis of mechanosensitivity

(2009) Stuart M. Brierley   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Primary afferents with TRPM8 and TRPA1 profiles target distinct subpopulations of rat superficial dorsal horn neurones

(2009) Paul J Wrigley et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Ion Channel TRPA1 Is Required for Normal Mechanosensation and Is Modulated by Algesic Stimuli

(2009) Stuart M. Brierley et al.   GASTROENTEROLOGY

TRP channels: new targets for visceral pain

(2009) L A Blackshaw et al.   GUT

The TRPV4 Cation Channel Mediates Stretch-evoked Ca2+Influx and ATP Release in Primary Urothelial Cell Cultures

(2009) Tsutomu Mochizuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma

(2009) A. I. Caceres et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of transient receptor potential A1 channel by phosphatidylinositol-4,5-bisphosphate

(2008) Donghee Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia

(2008) Walter E. B. Sipe et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Transient Receptor Potential Vanilloid-4 Has a Major Role in Visceral Hypersensitivity Symptoms

(2008) Nicolas Cenac et al.   GASTROENTEROLOGY

Selective Role for TRPV4 Ion Channels in Visceral Sensory Pathways

(2008) Stuart M. Brierley et al.   GASTROENTEROLOGY

Inhibition of TRPM8 by Icilin Distinct from Desensitization Induced by Menthol and Menthol Derivatives

(2008) Frank J. P. Kühn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of Transmembrane Domain 5 as a Critical Molecular Determinant of Menthol Sensitivity in Mammalian TRPA1 Channels

(2008) B. Xiao et al.   JOURNAL OF NEUROSCIENCE

Interaction of Transient Receptor Potential Vanilloid 4, Integrin, and Src Tyrosine Kinase in Mechanical Hyperalgesia

(2008) N. Alessandri-Haber et al.   JOURNAL OF NEUROSCIENCE

Gain-of-function mutations in TRPV4 cause autosomal dominant brachyolmia

(2008) Matthew J Rock et al.   NATURE GENETICS

Effects of chili on postprandial gastrointestinal symptoms in diarrhoea predominant irritable bowel syndrome: evidence for capsaicin-sensitive visceral nociception hypersensitivity

(2008) s. gonlachanvit et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4,5-biphosphate manipulators

(2008) Yuji Karashima et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY