Ability to Generate Patient-Derived Breast Cancer Xenografts Is Enhanced in Chemoresistant Disease and Predicts Poor Patient Outcomes

Gene mutations in primary tumors and corresponding patient-derived xenografts derived from non-small cell lung cancer

(2015) Chuncheng Hao et al.   CANCER LETTERS

Clinical Actionability Enhanced through Deep Targeted Sequencing of Solid Tumors

(2015) K. Chen et al.   CLINICAL CHEMISTRY

Tumorgrafts asIn VivoSurrogates for Women with Ovarian Cancer

(2014) S. John Weroha et al.   CLINICAL CANCER RESEARCH

Influence of Biospecimen Variables on Proteomic Biomarkers in Breast Cancer

(2014) F. Meric-Bernstam et al.   CLINICAL CANCER RESEARCH

A comprehensively characterized large panel of head and neck cancer patient-derived xenografts identifies the mTOR inhibitor everolimus as potential new treatment option

(2014) Konrad Klinghammer et al.   INTERNATIONAL JOURNAL OF CANCER

Concordance of Genomic Alterations between Primary and Recurrent Breast Cancer

(2014) F. Meric-Bernstam et al.   MOLECULAR CANCER THERAPEUTICS

Patient-Derived Xenograft Models: An Emerging Platform for Translational Cancer Research

(2014) M. Hidalgo et al.   Cancer Discovery

Setting up a wide panel of patient-derived tumor xenografts of non-small cell lung cancer by improving the preanalytical steps

(2014) Marius Ilie et al.   Cancer Medicine

A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models

(2013) X. Zhang et al.   CANCER RESEARCH

Origin of the vasculature supporting growth of primary patient tumor xenografts

(2013) Bonnie L Hylander et al.   Journal of Translational Medicine

Targeting the PI3-Kinase/Akt/mTOR Signaling Pathway

(2013) Burhan Hassan et al.   Surgical Oncology Clinics of North America

Characterization of a Large Panel of Patient-Derived Tumor Xenografts Representing the Clinical Heterogeneity of Human Colorectal Cancer

(2012) S. Julien et al.   CLINICAL CANCER RESEARCH

VarScan 2: Somatic mutation and copy number alteration discovery in cancer by exome sequencing

(2012) D. C. Koboldt et al.   GENOME RESEARCH

Patient-Derived Xenografts of Non Small Cell Lung Cancer: Resurgence of an Old Model for Investigation of Modern Concepts of Tailored Therapy and Cancer Stem Cells

(2012) Massimo Moro et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Genomic characterization of explant tumorgraft models derived from fresh patient tumor tissue

(2012) David J Monsma et al.   Journal of Translational Medicine

Histological and Molecular Evaluation of Patient-Derived Colorectal Cancer Explants

(2012) Joshua M. Uronis et al.   PLoS One

ROCK Inhibitor and Feeder Cells Induce the Conditional Reprogramming of Epithelial Cells

(2011) Xuefeng Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

Modeling of response to endocrine therapy in a panel of human luminal breast cancer xenografts

(2011) P. Cottu et al.   BREAST CANCER RESEARCH AND TREATMENT

Tumor Engraftment in Nude Mice and Enrichment in Stroma- Related Gene Pathways Predict Poor Survival and Resistance to Gemcitabine in Patients with Pancreatic Cancer

(2011) I. Garrido-Laguna et al.   CLINICAL CANCER RESEARCH

MK-1775, a Potent Wee1 Inhibitor, Synergizes with Gemcitabine to Achieve Tumor Regressions, Selectively in p53-Deficient Pancreatic Cancer Xenografts

(2011) N. V. Rajeshkumar et al.   CLINICAL CANCER RESEARCH

Prioritizing Phase I Treatment Options Through Preclinical Testing on Personalized Tumorgraft

(2011) M. Pia Morelli et al.   JOURNAL OF CLINICAL ONCOLOGY

A Pilot Clinical Study of Treatment Guided by Personalized Tumorgrafts in Patients with Advanced Cancer

(2011) M. Hidalgo et al.   MOLECULAR CANCER THERAPEUTICS

PI3K Pathway Mutations and PTEN Levels in Primary and Metastatic Breast Cancer

(2011) A. M. Gonzalez-Angulo et al.   MOLECULAR CANCER THERAPEUTICS

Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes

(2011) Yoko S DeRose et al.   NATURE MEDICINE

Genome-scale analysis of replication timing: from bench to bioinformatics

(2011) Tyrone Ryba et al.   Nature Protocols

Selective Genomic Copy Number Imbalances and Probability of Recurrence in Early-Stage Breast Cancer

(2011) Patricia A. Thompson et al.   PLoS One

Quantifying the relative amount of mouse and human DNA in cancer xenografts using species-specific variation in gene length

(2010) Ming-Tseh Lin et al.   BIOTECHNIQUES

Predictors of Tumor Progression During Neoadjuvant Chemotherapy in Breast Cancer

(2010) Abigail S. Caudle et al.   JOURNAL OF CLINICAL ONCOLOGY

Genome remodelling in a basal-like breast cancer metastasis and xenograft

(2010) Li Ding et al.   NATURE

Prognostic impact of discordance between triple-receptor measurements in primary and recurrent breast cancer

(2009) C. Liedtke et al.   ANNALS OF ONCOLOGY

Molecular profiling and characterization of luminal-like and basal-like in vivo breast cancer xenograft models

(2009) Anna Bergamaschi et al.   Molecular Oncology

Gene expression patterns within cell lines are predictive of chemosensitivity

(2008) Brian Z Ring et al.   BMC GENOMICS

Comparison of Akt/mTOR signaling in primary breast tumors and matched distant metastases

(2008) Argun Akcakanat et al.   CANCER

Response to Neoadjuvant Therapy and Long-Term Survival in Patients With Triple-Negative Breast Cancer

(2008) Cornelia Liedtke et al.   JOURNAL OF CLINICAL ONCOLOGY

From Human to Mouse and Back: 'Tumorgraft' Models Surge in Popularity

(2008) K. Garber   JNCI-Journal of the National Cancer Institute

Intrinsic Resistance of Tumorigenic Breast Cancer Cells to Chemotherapy

(2008) X. Li et al.   JNCI-Journal of the National Cancer Institute