Modeling the Role of the Glymphatic Pathway and Cerebral Blood Vessel Properties in Alzheimer’s Disease Pathogenesis

Cleavage of amyloid precursor protein by an archaeal presenilin homologue PSH

(2015) Shangyu Dang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blood–brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment

(2015) Mina Elahy et al.   Immunity & Ageing

Impairment of paravascular clearance pathways in the aging brain

(2014) Benjamin T. Kress et al.   ANNALS OF NEUROLOGY

Highly potent soluble amyloid-β seeds in human Alzheimer brain but not cerebrospinal fluid

(2014) Sarah K. Fritschi et al.   BRAIN

ApoE and Aβ in Alzheimer’s Disease: Accidental Encounters or Partners?

(2014) Takahisa Kanekiyo et al.   NEURON

The Cerebrovascular Basement Membrane: Role in the Clearance of β-amyloid and Cerebral Amyloid Angiopathy

(2014) Alan W. J. Morris et al.   Frontiers in Aging Neuroscience

LRP-1 polymorphism is associated with global and regional amyloid load in Alzheimer's disease in humans in-vivo

(2014) Timo Grimmer et al.   NeuroImage-Clinical

Oligomers, fact or artefact? SDS-PAGE induces dimerization of β-amyloid in human brain samples

(2013) Andrew D. Watt et al.   ACTA NEUROPATHOLOGICA

Contributions of Degradation and Brain-to-blood Elimination Across the Blood—Brain Barrier to Cerebral Clearance of Human Amyloid-β Peptide(1-40) in Mouse Brain

(2013) Shingo Ito et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cerebral Arterial Pulsation Drives Paravascular CSF-Interstitial Fluid Exchange in the Murine Brain

(2013) J. J. Iliff et al.   JOURNAL OF NEUROSCIENCE

ApoE influences amyloid-  (A ) clearance despite minimal apoE/A  association in physiological conditions

(2013) P. B. Verghese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Garbage Truck of the Brain

(2013) M. Nedergaard   SCIENCE

Sleep Drives Metabolite Clearance from the Adult Brain

(2013) L. Xie et al.   SCIENCE

The density difference between tissue and neural probes is a key factor for glial scarring

(2013) Gustav Lind et al.   Scientific Reports

Evidence for impaired amyloid β clearance in Alzheimer's disease

(2013) Kristin R Wildsmith et al.   Alzheimers Research & Therapy

Inflammation in Alzheimer Disease--A Brief Review of the Basic Science and Clinical Literature

(2013) T. Wyss-Coray et al.   Cold Spring Harbor Perspectives in Medicine

Mechanisms of Amyloid-β Peptide Clearance: Potential Therapeutic Targets for Alzheimer's Disease

(2012) Sang-Sun Yoon et al.   Biomolecules & Therapeutics

Amyloid-β-dependent compromise of microvascular structure and function in a model of Alzheimer’s disease

(2012) Adrienne Dorr et al.   BRAIN

A Multifaceted Role for apoE in the Clearance of Beta-Amyloid across the Blood-Brain Barrier

(2012) Corbin Bachmeier et al.   Neurodegenerative Diseases

Disruption of Arterial Perivascular Drainage of Amyloid-β from the Brains of Mice Expressing the Human APOE ε4 Allele

(2012) Cheryl A. Hawkes et al.   PLoS One

Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood A  clearance in a mouse model of  -amyloidosis

(2012) J. M. Castellano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Human apoE Isoforms Differentially Regulate Brain Amyloid-  Peptide Clearance

(2011) J. M. Castellano et al.   Science Translational Medicine

Image Analysis of Endothelial Microstructure and Endothelial Cell Dimensions of Human Arteries - A Preliminary Study

(2010) Bora Garipcan et al.   ADVANCED ENGINEERING MATERIALS

Aging and cerebrovascular dysfunction: contribution of hypertension, cerebral amyloid angiopathy, and immunotherapy

(2010) Vitaly Vasilevko et al.   Annals of the New York Academy of Sciences

β -Amyloid: A Disease Target or a Synaptic Regulator Affecting Age-Related Neurotransmitter Changes?

(2010) E. Mura et al.   CURRENT PHARMACEUTICAL DESIGN

Aggregation of amyloid Aβ(1-40) peptide in perdeuterated 2,2,2-trifluoroethanol caused by ultrasound sonication

(2010) Andrei V. Filippov et al.   MAGNETIC RESONANCE IN CHEMISTRY

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mathematical Modeling for the Pathogenesis of Alzheimer's Disease

(2010) Ishwar K. Puri et al.   PLoS One

MRI of hippocampal volume loss in early Alzheimer's disease in relation to ApoE genotype and biomarkers

(2009) N. Schuff et al.   BRAIN

Monitoring of brain interstitial total tau and beta amyloid proteins by microdialysis in patients with traumatic brain injury

(2009) Niklas Marklund et al.   JOURNAL OF NEUROSURGERY

Beta-Amyloid Deposition and the Aging Brain

(2009) Karen M. Rodrigue et al.   NEUROPSYCHOLOGY REVIEW

Plasma β-Amyloid 1-40 Is Associated With the Diffuse Small Vessel Disease Subtype

(2009) Meritxell Gomis et al.   STROKE

Cerebral amyloid angiopathy in the aetiology and immunotherapy of Alzheimer disease

(2009) Roy O Weller et al.   Alzheimers Research & Therapy

The Role of the Cell Surface LRP and Soluble LRP in Blood-Brain Barrier Aβ Clearance in Alzheimers Disease

(2008) R. Deane et al.   CURRENT PHARMACEUTICAL DESIGN

Alzheimer’s disease, cerebrovascular dysfunction and the benefits of exercise: From vessels to neurons

(2008) Christian Lange-Asschenfeldt et al.   EXPERIMENTAL GERONTOLOGY

Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS

(2008) Robert W. Mahley et al.   JOURNAL OF LIPID RESEARCH

Neocortical glial cell numbers in human brains

(2007) D.P. Pelvig et al.   NEUROBIOLOGY OF AGING