Functional Impact of 14 Single Nucleotide Polymorphisms Causing Missense Mutations of Human α7 Nicotinic Receptor

The analgesic-like properties of the alpha7 nAChR silent agonist NS6740 is associated with non-conducting conformations of the receptor

(2015) Roger L. Papke et al.   NEUROPHARMACOLOGY

Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor

(2015) Radovan Spurny et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The therapeutic promise of positive allosteric modulation of nicotinic receptors

(2014) Victor V. Uteshev   EUROPEAN JOURNAL OF PHARMACOLOGY

Molecular Recognition of the Neurotransmitter Acetylcholine by an Acetylcholine Binding Protein Reveals Determinants of Binding to Nicotinic Acetylcholine Receptors

(2014) Jeppe A. Olsen et al.   PLoS One

The cholinergic anti-inflammatory pathway: A critical review

(2013) D. Martelli et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

The Activity of GAT107, an Allosteric Activator and Positive Modulator of α7 Nicotinic Acetylcholine Receptors (nAChR), Is Regulated by Aromatic Amino Acids That Span the Subunit Interface

(2013) Roger L. Papke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signal Transduction Pathways in the Pentameric Ligand-Gated Ion Channels

(2013) David Mowrey et al.   PLoS One

Stoichiometry for activation of neuronal  7 nicotinic receptors

(2013) N. Andersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional anatomy of an allosteric protein

(2013) Prasad Purohit et al.   Nature Communications

An interaction between α7 nicotinic receptors and a G-protein pathway complex regulates neurite growth in neural cells

(2012) Jacob C. Nordman et al.   JOURNAL OF CELL SCIENCE

Sources of energy for gating by neurotransmitters in acetylcholine receptor channels

(2012) P. Purohit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Investigation of the Molecular Mechanism of the  7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator PNU-120596 Provides Evidence for Two Distinct Desensitized States

(2011) D. K. Williams et al.   MOLECULAR PHARMACOLOGY

Agonist activation of  7 nicotinic acetylcholine receptors via an allosteric transmembrane site

(2011) J. K. Gill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of loop 9 on the function of neuronal nicotinic receptors

(2010) Manuel Criado et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Stimulation of  7 Nicotinic Acetylcholine Receptor by Nicotine Increases Suppressive Capacity of Naturally Occurring CD4+CD25+ Regulatory T Cells in Mice In Vitro

(2010) D.-w. Wang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Regulation of Glutamate Release by  7 Nicotinic Receptors: Differential Role in Methamphetamine-Induced Damage to Dopaminergic and Serotonergic Terminals

(2010) N. A. Northrop et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Allosteric activation mechanism of the cys-loop receptors

(2009) Yong-chang Chang et al.   ACTA PHARMACOLOGICA SINICA

Differential Regulation of Receptor Activation and Agonist Selectivity by Highly Conserved Tryptophans in the Nicotinic Acetylcholine Receptor Binding Site

(2009) D. K. Williams et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The cholinergic anti-inflammatory pathway: towards innovative treatment of rheumatoid arthritis

(2009) Marjolein A. van Maanen et al.   Nature Reviews Rheumatology

Positive Allosteric Modulation of the  7 Nicotinic Acetylcholine Receptor: Ligand Interactions with Distinct Binding Sites and Evidence for a Prominent Role of the M2-M3 Segment

(2008) D. Bertrand et al.   MOLECULAR PHARMACOLOGY

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

(2008) Nicolas Bocquet et al.   NATURE

A recurrent 15q13.3 microdeletion syndrome associated with mental retardation and seizures

(2008) Andrew J Sharp et al.   NATURE GENETICS

Native glycine receptor subtypes and their physiological roles

(2008) Joseph W. Lynch   NEUROPHARMACOLOGY

GABAA receptors: Subtypes provide diversity of function and pharmacology

(2008) Richard W. Olsen et al.   NEUROPHARMACOLOGY

International Union of Pharmacology. LXX. Subtypes of  -Aminobutyric AcidA Receptors: Classification on the Basis of Subunit Composition, Pharmacology, and Function. Update

(2008) R. W. Olsen et al.   PHARMACOLOGICAL REVIEWS

Potentiation of  7 nicotinic acetylcholine receptors via an allosteric transmembrane site

(2008) G. T. Young et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation

(2007) W J Jonge et al.   BRITISH JOURNAL OF PHARMACOLOGY

Aromatic residues at position 55 of rat α7 nicotinic acetylcholine receptors are critical for maintaining rapid desensitization

(2007) Elaine A. Gay et al.   JOURNAL OF PHYSIOLOGY-LONDON