In Vivo Silencing of A20 via TLR9-Mediated Targeted SiRNA Delivery Potentiates Antitumor Immune Response

CTLA4 aptamer delivers STAT3 siRNA to tumor-associated and malignant T cells

(2014) Andreas Herrmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Attenuated Expression of A20 Markedly Increases the Efficacy of Double-Stranded RNA-Activated Dendritic Cells As an Anti-Cancer Vaccine

(2014) K. Breckpot et al.   JOURNAL OF IMMUNOLOGY

The tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20) imposes a brake on antitumor activity of CD8 T cells

(2014) M. Giordano et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular basis for improved gene silencing by Dicer substrate interfering RNA compared with other siRNA variants

(2013) Nicholas M. Snead et al.   NUCLEIC ACIDS RESEARCH

An Optimized microRNA Backbone for Effective Single-Copy RNAi

(2013) Christof Fellmann et al.   Cell Reports

Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis

(2011) S Lippens et al.   CELL DEATH AND DIFFERENTIATION

The Ubiquitin-Editing Protein A20 Prevents Dendritic Cell Activation, Recognition of Apoptotic Cells, and Systemic Autoimmunity

(2011) Mirjam Kool et al.   IMMUNITY

A20 edits ubiquitin and autoimmune paradigms

(2011) Flavius Martin et al.   NATURE GENETICS

RNA interference with 2′,4′-bridged nucleic acid analogues

(2010) S.M. Abdur Rahman et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor–induced toxicity and experimental colitis

(2010) Lars Vereecke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Role of Ubiquitin in NF-κB Regulatory Pathways

(2009) Brian Skaug et al.   Annual Review of Biochemistry

A20 takes on tumors: tumor suppression by an ubiquitin-editing enzyme

(2009) Barbara A. Malynn et al.   JOURNAL OF EXPERIMENTAL MEDICINE

In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses

(2009) Marcin Kortylewski et al.   NATURE BIOTECHNOLOGY

A20deletion is associated with copy number gain at theTNFA/B/Clocus and occurs preferentially in translocation-negative MALT lymphoma of the ocular adnexa and salivary glands

(2008) E Chanudet et al.   JOURNAL OF PATHOLOGY

A20 is an antigen presentation attenuator and its inhibition overcomes regulatory T cell–mediated suppression

(2008) Xiao-Tong Song et al.   NATURE MEDICINE