Sparse Modeling Reveals miRNA Signatures for Diagnostics of Inflammatory Bowel Disease

Genetic studies of Crohn's disease: Past, present and future

(2014) Jimmy Z. Liu et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

TH9 cells that express the transcription factor PU.1 drive T cell–mediated colitis via IL-9 receptor signaling in intestinal epithelial cells

(2014) Katharina Gerlach et al.   NATURE IMMUNOLOGY

miR-122 targets NOD2 to decrease intestinal epithelial cell injury in Crohn’s disease

(2013) Yu Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Overexpression of miR-21 in patients with ulcerative colitis impairs intestinal epithelial barrier function through targeting the Rho GTPase RhoB

(2013) Yongzhi Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Identification of serum and tissue micro-RNA expression profiles in different stages of inflammatory bowel disease

(2013) M. Iborra et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

MicroRNA-124 Regulates STAT3 Expression and Is Down-regulated in Colon Tissues of Pediatric Patients With Ulcerative Colitis

(2013) Georgios Koukos et al.   GASTROENTEROLOGY

MicroRNA-224 Negatively Regulates p21 Expression During Late Neoplastic Progression in Inflammatory Bowel Disease

(2013) Alexandru V. Olaru et al.   INFLAMMATORY BOWEL DISEASES

NOD2 Expression is Regulated by microRNAs in Colonic Epithelial HCT116 Cells

(2013) Alice Y. Chuang et al.   INFLAMMATORY BOWEL DISEASES

Comprehensive analysis of microRNA profiles in multiple sclerosis including next-generation sequencing

(2013) Andreas Keller et al.   Multiple Sclerosis Journal

miRTarBase update 2014: an information resource for experimentally validated miRNA-target interactions

(2013) Sheng-Da Hsu et al.   NUCLEIC ACIDS RESEARCH

ErbB receptors and their growth factor ligands in pediatric intestinal inflammation

(2013) Mark R. Frey et al.   PEDIATRIC RESEARCH

Whole Genome Gene Expression Meta-Analysis of Inflammatory Bowel Disease Colon Mucosa Demonstrates Lack of Major Differences between Crohn's Disease and Ulcerative Colitis

(2013) Atle van Beelen Granlund et al.   PLoS One

MicroRNA-21 Knockout Improve the Survival Rate in DSS Induced Fatal Colitis through Protecting against Inflammation and Tissue Injury

(2013) Chenzhang Shi et al.   PLoS One

Intestinal DMBT1 Expression Is Modulated by Crohn’s Disease-Associated IL23R Variants and by a DMBT1 Variant Which Influences Binding of the Transcription Factors CREB1 and ATF-2

(2013) Julia Diegelmann et al.   PLoS One

miRNA Signatures in Sera of Patients with Active Pulmonary Tuberculosis

(2013) Paolo Miotto et al.   PLoS One

Gene Expression Analysis of Peripheral Cells for Subclassification of Pediatric Inflammatory Bowel Disease in Remission

(2013) Pieter P. E. van Lierop et al.   PLoS One

Identification of Novel Predictor Classifiers for Inflammatory Bowel Disease by Gene Expression Profiling

(2013) Trinidad Montero-Meléndez et al.   PLoS One

miR-200b inhibits TGF-β1-induced epithelial-mesenchymal transition and promotes growth of intestinal epithelial cells

(2013) Y Chen et al.   Cell Death & Disease

A Panel of Four miRNAs Accurately Differentiates Malignant from Benign Indeterminate Thyroid Lesions on Fine Needle Aspiration

(2012) X. M. Keutgen et al.   CLINICAL CANCER RESEARCH

Targeting PI3K isoforms and SHIP in the immune system: new therapeutics for inflammation and leukemia

(2012) Matthew D Blunt et al.   CURRENT OPINION IN PHARMACOLOGY

Association between genetic variants in the HNF4A gene and childhood-onset Crohn’s disease

(2012) V Marcil et al.   GENES AND IMMUNITY

Association of the RAVER2 gene with increased susceptibility for ulcerative colitis

(2012) D. Bouzid et al.   HUMAN IMMUNOLOGY

Differential MicroRNA expression tracks neoplastic progression in inflammatory bowel disease-associated colorectal cancer

(2012) Ziad Kanaan et al.   HUMAN MUTATION

Bioinformatics analysis reveals transcriptome and microRNA signatures and drug repositioning targets for IBD and other autoimmune diseases

(2012) Peter M. Clark et al.   INFLAMMATORY BOWEL DISEASES

Circulating MicroRNA in inflammatory bowel disease

(2012) Archanioti Paraskevi et al.   Journal of Crohns & Colitis

Inflammatory gene expression profiles in Crohn's disease and ulcerative colitis: A comparative analysis using a reverse transcriptase multiplex ligation-dependent probe amplification protocol

(2012) Serban Gologan et al.   Journal of Crohns & Colitis

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Genome-Wide Maps of Circulating miRNA Biomarkers for Ulcerative Colitis

(2012) Radha Duttagupta et al.   PLoS One

MicroRNA Expression Profiles of Whole Blood in Lung Adenocarcinoma

(2012) Santosh K. Patnaik et al.   PLoS One

Up-Regulation of microRNA-126 May Contribute to Pathogenesis of Ulcerative Colitis via Regulating NF-kappaB Inhibitor IκBα

(2012) Xiao Feng et al.   PLoS One

Biomarkers in inflammatory bowel disease: current practices and recent advances

(2012) Heba N. Iskandar et al.   Translational Research

PDCD4/miR-21 dysregulation in inflammatory bowel disease-associated carcinogenesis

(2012) Kathrin Ludwig et al.   VIRCHOWS ARCHIV

Elastic SCAD as a novel penalization method for SVM classification tasks in high-dimensional data

(2011) Natalia Becker et al.   BMC BIOINFORMATICS

Different miRNA signatures of oral and pharyngeal squamous cell carcinomas: a prospective translational study

(2011) C B Lajer et al.   BRITISH JOURNAL OF CANCER

The Utility of Biomarkers in the Diagnosis and Therapy of Inflammatory Bowel Disease

(2011) James D. Lewis   GASTROENTEROLOGY

IL-23 Receptor Regulation by Let-7f in Human CD4+ Memory T Cells

(2011) Z. Li et al.   JOURNAL OF IMMUNOLOGY

Role of miR-150-targeting c-Myb in colonic epithelial disruption during dextran sulphate sodium-induced murine experimental colitis and human ulcerative colitis

(2011) Zhen Bian et al.   JOURNAL OF PATHOLOGY

Circulating MicroRNA Is a Biomarker of Pediatric Crohn Disease

(2011) Adam M Zahm et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Next-generation sequencing identifies novel microRNAs in peripheral blood of lung cancer patients

(2011) Andreas Keller et al.   Molecular BioSystems

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

(2011) Patrick Brest et al.   NATURE GENETICS

Notch-1 Signaling Regulates Intestinal Epithelial Barrier Function, Through Interaction With CD4+ T Cells, in Mice and Humans

(2010) Stephanie Dahan et al.   GASTROENTEROLOGY

Identification of microRNAs associated with ileal and colonic Crohnʼs disease†

(2010) Feng Wu et al.   INFLAMMATORY BOWEL DISEASES

Peripheral blood MicroRNAs distinguish active ulcerative colitis and Crohnʼs disease

(2010) Feng Wu et al.   INFLAMMATORY BOWEL DISEASES

Dynamic changes in the expression of MicroRNA-31 during inflammatory bowel disease-associated neoplastic transformation

(2010) Alexandru V. Olaru et al.   INFLAMMATORY BOWEL DISEASES

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Identification of Restricted Subsets of Mature microRNA Abnormally Expressed in Inactive Colonic Mucosa of Patients with Inflammatory Bowel Disease

(2010) Magali Fasseu et al.   PLoS One

penalizedSVM: a R-package for feature selection SVM classification

(2009) Natalia Becker et al.   BIOINFORMATICS

Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region

(2009) Jeffrey C Barrett et al.   NATURE GENETICS

Multiple Sclerosis: MicroRNA Expression Profiles Accurately Differentiate Patients with Relapsing-Remitting Disease from Healthy Controls

(2009) Andreas Keller et al.   PLoS One

Interpretation of Genetic Association Studies: Markers with Replicated Highly Significant Odds Ratios May Be Poor Classifiers

(2009) Johanna Jakobsdottir et al.   PLoS Genetics

A novel mTOR inhibitor is efficacious in a murine model of colitis

(2008) Mandar R. Bhonde et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

MicroRNAs Are Differentially Expressed in Ulcerative Colitis and Alter Expression of Macrophage Inflammatory Peptide-2α

(2008) Feng Wu et al.   GASTROENTEROLOGY

Microfluidic-based enzymatic on-chip labeling of miRNAs

(2008) Sonja Vorwerk et al.   New Biotechnology

Elevated insulin-like growth factor 1 receptor, hepatocyte growth factor receptor and telomerase protein expression in mild ulcerative colitis

(2008) Ferenc Sipos et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY