A Nano-MgO and Ionic Liquid-Catalyzed ‘Green’ Synthesis Protocol for the Development of Adamantyl-Imidazolo-Thiadiazoles as Anti-Tuberculosis Agents Targeting Sterol 14α-Demethylase (CYP51)
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A Nano-MgO and Ionic Liquid-Catalyzed ‘Green’ Synthesis Protocol for the Development of Adamantyl-Imidazolo-Thiadiazoles as Anti-Tuberculosis Agents Targeting Sterol 14α-Demethylase (CYP51)
Authors
Keywords
Mycobacterium tuberculosis, Sterols, Root structure, Tuberculosis, Small molecules, Organic solvents, Single crystals, Streptomycin
Journal
PLoS One
Volume 10, Issue 10, Pages e0139798
Publisher
Public Library of Science (PLoS)
Online
2015-10-16
DOI
10.1371/journal.pone.0139798
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Novel synthetic coumarins that targets NF-κB in Hepatocellular carcinoma
- (2015) Mahabaleshwaraiah Neelgundmath et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Microwave-assisted synthesis, characterization and cytotoxic studies of novel estrogen receptor α ligands towards human breast cancer cells
- (2015) Hanumantharayappa Bharathkumar et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Drug-resistance mechanisms and tuberculosis drugs
- (2015) Claudio U Köser et al. LANCET
- Design, synthesis and evaluation of 1,2,3-triazole-adamantylacetamide hybrids as potent inhibitors of Mycobacterium tuberculosis
- (2014) Dinesh Addla et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- MgO nanoparticles as antibacterial agent: preparation and activity
- (2014) Zhen-Xing Tang et al. BRAZILIAN JOURNAL OF CHEMICAL ENGINEERING
- Design, Synthesis, and Evaluation of New Thiadiazole-Based Direct Inhibitors of Enoyl Acyl Carrier Protein Reductase (InhA) for the Treatment of Tuberculosis
- (2014) Roman Šink et al. JOURNAL OF MEDICINAL CHEMISTRY
- A New Ibuprofen Derivative Inhibits Platelet Aggregation and ROS Mediated Platelet Apoptosis
- (2014) Kodagahalli S. Rakesh et al. PLoS One
- Synthesis and Characterization of Novel 2-Amino-Chromene-Nitriles that Target Bcl-2 in Acute Myeloid Leukemia Cell Lines
- (2014) Hosadurga K. Keerthy et al. PLoS One
- The Lipophilic Bullet Hits the Targets: Medicinal Chemistry of Adamantane Derivatives
- (2013) Lukas Wanka et al. CHEMICAL REVIEWS
- In Vitro Characterization of the Anti-Bacterial Activity of SQ109 against Helicobacter pylori
- (2013) Morris O. Makobongo et al. PLoS One
- Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability
- (2012) Michael S. Scherman et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis, Biological Evaluation, and Structure-activity Relationship of Clonazepam, Meclonazepam, and 1,4-Benzodiazepine Compounds with Schistosomicidal Activity
- (2012) Carla M. S. Menezes et al. Chemical Biology & Drug Design
- EUCAST Technical Note on Aspergillus and amphotericin B, itraconazole, and posaconazole
- (2012) M.C. Arendrup et al. CLINICAL MICROBIOLOGY AND INFECTION
- Anticancer Drug Design Using Scaffolds of β-Lactams, Sulfonamides, Quinoline, Quinoxaline and Natural Products. Drugs Advances in Clinical Trials
- (2012) I. Balderas-Renteria et al. CURRENT MEDICINAL CHEMISTRY
- Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action
- (2012) Katherine A Sacksteder et al. Future Microbiology
- ShelXle: a Qt graphical user interface forSHELXL
- (2011) Christian B. Hübschle et al. JOURNAL OF APPLIED CRYSTALLOGRAPHY
- Design of the Anti-tuberculosis Drugs induced Adverse Reactions in China National Tuberculosis Prevention and Control Scheme Study (ADACS)
- (2010) Yin Yin Xia et al. BMC PUBLIC HEALTH
- Nano-MgO: An Efficient Catalyst for the Synthesis of Formamides from Amines and Formic Acid Under MWI
- (2010) M. B. Madhusudana Reddy et al. CATALYSIS LETTERS
- Structure validation in chemical crystallography
- (2009) Anthony L. Spek ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Trypanosoma cruzi CYP51 Inhibitor Derived from a Mycobacterium tuberculosis Screen Hit
- (2009) Chiung-Kuang Chen et al. PLoS Neglected Tropical Diseases
- Protonate3D: Assignment of ionization states and hydrogen coordinates to macromolecular structures
- (2008) Paul Labute PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug
- (2004) Lee Jia et al. BRITISH JOURNAL OF PHARMACOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More