The Stapled AKAP Disruptor Peptide STAD-2 Displays Antimalarial Activity through a PKA-Independent Mechanism

Isoform-Selective Disruption of AKAP-Localized PKA Using Hydrocarbon Stapled Peptides

(2014) Yuxiao Wang et al.   ACS Chemical Biology

Cell-Penetrating Peptides: Design, Synthesis, and Applications

(2014) Dana Maria Copolovici et al.   ACS Nano

Malaria

(2014) G.D. Burchard   INTERNIST

Hydrocarbon-Stapled Peptides: Principles, Practice, and Progress

(2014) Loren D. Walensky et al.   JOURNAL OF MEDICINAL CHEMISTRY

Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system

(2014) Mehdi Ghorbal et al.   NATURE BIOTECHNOLOGY

Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

(2014) Elizabeth A. Ashley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Spiroindolone KAE609 for Falciparum and Vivax Malaria

(2014) Nicholas J. White et al.   NEW ENGLAND JOURNAL OF MEDICINE

Use of Peptide Nucleic Acids to Manipulate Gene Expression in the Malaria Parasite Plasmodium falciparum

(2014) Netanel Kolevzon et al.   PLoS One

Proteolysis at a Specific Extracellular Residue Implicates Integral Membrane CLAG3 in Malaria Parasite Nutrient Channels

(2014) Wang Nguitragool et al.   PLoS One

Understanding the Mechanism of Atovaquone Drug Resistance in Plasmodium falciparum Cytochrome b Mutation Y268S Using Computational Methods

(2014) Bashir A. Akhoon et al.   PLoS One

Why do malaria parasites increase host erythrocyte permeability?

(2014) Sanjay A. Desai   TRENDS IN PARASITOLOGY

ATP, an extracellular signaling molecule in red blood cells: A messenger for malaria?

(2014) Gordon Langsley et al.   Biomedical Journal

Cell-Permeable Stapled Peptides Based on HIV-1 Integrase Inhibitors Derived from HIV-1 Gene Products

(2013) Wataru Nomura et al.   ACS Chemical Biology

Improved Efficacy of Fosmidomycin against Plasmodium and Mycobacterium Species by Combination with the Cell-Penetrating Peptide Octaarginine

(2013) Christof Sparr et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antiapicoplast and Gametocytocidal Screening To Identify the Mechanisms of Action of Compounds within the Malaria Box

(2013) Jessica D. Bowman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Stapled peptide-based membrane fusion inhibitors of hepatitis C virus

(2013) Hong-Kui Cui et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

(2013) Frédéric Ariey et al.   NATURE

Disrupting malaria parasite AMA1–RON2 interaction with a small molecule prevents erythrocyte invasion

(2013) Prakash Srinivasan et al.   Nature Communications

Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent

(2013) Amaravadhi Harikishore et al.   Scientific Reports

Effect of hydrocarbon stapling on the properties of α-helical antimicrobial peptides isolated from the venom of hymenoptera

(2012) Hubert Chapuis et al.   AMINO ACIDS

Creating Order from Chaos: Cellular Regulation by Kinase Anchoring

(2012) John D. Scott et al.   Annual Review of Pharmacology and Toxicology

Plasmodiumkinases as targets for new-generation antimalarials

(2012) Isabelle S Lucet et al.   Future Medicinal Chemistry

Cytochrome b Mutation Y268S Conferring Atovaquone Resistance Phenotype in Malaria Parasite Results in Reduced Parasite bc 1 Catalytic Turnover and Protein Expression

(2012) Nicholas Fisher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stabilizing supply of artemisinin and artemisinin-based combination therapy in an era of wide-spread scale-up

(2012) Rima Shretta et al.   MALARIA JOURNAL

Exploring the Plasmodium falciparum cyclic-adenosine monophosphate (cAMP)-dependent protein kinase (PfPKA) as a therapeutic target

(2012) Nina M. Haste et al.   MICROBES AND INFECTION

Malaria Parasite clag3 Genes Determine Channel-Mediated Nutrient Uptake by Infected Red Blood Cells

(2011) Wang Nguitragool et al.   CELL

On the Mechanism of Eukaryotic Cell Penetration by α- and β-Oligoarginines - Targeting Infected Erythro­cytes

(2011) Faustin Kamena et al.   CHEMISTRY & BIODIVERSITY

AKAP2 anchors PKA with aquaporin-0 to support ocular lens transparency

(2011) Matthew G. Gold et al.   EMBO Molecular Medicine

Drug-resistant malaria: Molecular mechanisms and implications for public health

(2011) Ines Petersen et al.   FEBS LETTERS

PfMDR1: Mechanisms of Transport Modulation by Functional Polymorphisms

(2011) Pedro Eduardo Ferreira et al.   PLoS One

Malaria antifolate resistance with contrasting Plasmodium falciparum dihydrofolate reductase (DHFR) polymorphisms in humans and Anopheles mosquitoes

(2011) S. Mharakurwa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spirotetrahydro β-Carbolines (Spiroindolones): A New Class of Potent and Orally Efficacious Compounds for the Treatment of Malaria

(2010) Bryan K. S. Yeung et al.   JOURNAL OF MEDICINAL CHEMISTRY

Thousands of chemical starting points for antimalarial lead identification

(2010) Francisco-Javier Gamo et al.   NATURE

Erratum: Artemisinin resistance: current status and scenarios for containment

(2010) Arjen M. Dondorp et al.   NATURE REVIEWS MICROBIOLOGY

cAMP-dependent protein kinase from Plasmodium falciparum: an update

(2010) NATHALIE WURTZ et al.   PARASITOLOGY

On the Mechanism of Chloroquine Resistance in Plasmodium falciparum

(2010) Mauro Chinappi et al.   PLoS One

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anion channels in Plasmodium-falciparum-infected erythrocytes and protein kinase A

(2009) Anaïs Merckx et al.   TRENDS IN PARASITOLOGY

AKAP220 colocalizes with AQP2 in the inner medullary collecting ducts

(2008) Rie Okutsu et al.   KIDNEY INTERNATIONAL

Plasmodium falciparum Regulatory Subunit of cAMP-Dependent PKA and Anion Channel Conductance

(2008) Anaïs Merckx et al.   PLoS Pathogens