Tailoring the Antibody Response to Aggregated Aß Using Novel Alzheimer-Vaccines

Next-generation active immunization approach for synucleinopathies: implications for Parkinson’s disease clinical trials

(2014) Markus Mandler et al.   ACTA NEUROPATHOLOGICA

MER5101, a Novel A 1-15:DT Conjugate Vaccine, Generates a Robust Anti-A  Antibody Response and Attenuates A  Pathology and Cognitive Deficits in APPswe/PS1 E9 Transgenic Mice

(2013) B. Liu et al.   JOURNAL OF NEUROSCIENCE

Neurotoxicity of Amyloid  -Protein: Synaptic and Network Dysfunction

(2013) L. Mucke et al.   Cold Spring Harbor Perspectives in Medicine

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

AFFITOME® technology in neurodegenerative diseases: The doubling advantage

(2011) Achim Schneeberger et al.   Human vaccines & immunotherapeutics

The Second-Generation Active A  Immunotherapy CAD106 Reduces Amyloid Accumulation in APP Transgenic Mice While Minimizing Potential Side Effects

(2011) C. Wiessner et al.   JOURNAL OF NEUROSCIENCE

Revising the definition of Alzheimer's disease: a new lexicon

(2010) Bruno Dubois et al.   LANCET NEUROLOGY

Aβ oligomers inhibit synapse remodelling necessary for memory consolidation

(2010) Darragh B. Freir et al.   NEUROBIOLOGY OF AGING

Cognitive effects of cell-derived and synthetically derived Aβ oligomers

(2010) Miranda N. Reed et al.   NEUROBIOLOGY OF AGING

Update on Paraneoplastic and Autoimmune Disorders of the Central Nervous System

(2010) Myrna Rosenfeld et al.   SEMINARS IN NEUROLOGY

Immunotherapy, Vascular Pathology, and Microhemorrhages in Transgenic Mice

(2009) Donna Wilcock et al.   CNS & Neurological Disorders-Drug Targets

Amyloid Reduction by Amyloid-  Vaccination Also Reduces Mouse Tau Pathology and Protects from Neuron Loss in Two Mouse Models of Alzheimer's Disease

(2009) D. M. Wilcock et al.   JOURNAL OF NEUROSCIENCE

 -Amyloid Monomers Are Neuroprotective

(2009) M. L. Giuffrida et al.   JOURNAL OF NEUROSCIENCE

Soluble fibrillar oligomer levels are elevated in Alzheimer's disease brain and correlate with cognitive dysfunction

(2009) Jennifer L. Tomic et al.   NEUROBIOLOGY OF DISEASE

Aβ40 promotes neuronal cell fate in neural progenitor cells

(2008) Y Chen et al.   CELL DEATH AND DIFFERENTIATION

Aβ1–42 stimulates adult SVZ neurogenesis through the p75 neurotrophin receptor

(2008) Areechun Sotthibundhu et al.   NEUROBIOLOGY OF AGING

Endogenous secreted amyloid precursor protein-α regulates hippocampal NMDA receptor function, long-term potentiation and spatial memory

(2008) Chanel J. Taylor et al.   NEUROBIOLOGY OF DISEASE

Progress in the Active Immunotherapeutic Approach to Alzheimer’s Disease: Clinical Investigations into AN1792-Associated Meningoencephalitis

(2008) Michael Pride et al.   Neurodegenerative Diseases