Engineered chloroplast dsRNA silencescytochrome p450 monooxygenase,V-ATPaseandchitin synthasegenes in the insect gut and disruptsHelicoverpa armigeralarval development and pupation

Suppression of inhibitor formation against FVIII in a murine model of hemophilia A by oral delivery of antigens bioencapsulated in plant cells

(2014) A. Sherman et al.   BLOOD

Oral Delivery of Angiotensin-Converting Enzyme 2 and Angiotensin-(1-7) Bioencapsulated in Plant Cells Attenuates Pulmonary Hypertension

(2014) Vinayak Shenoy et al.   HYPERTENSION

Oral Delivery of ACE2/Ang-(1–7) Bioencapsulated in Plant Cells Protects against Experimental Uveitis and Autoimmune Uveoretinitis

(2014) Pollob K Shil et al.   MOLECULAR THERAPY

Expression of γ-tocopherol methyltransferase in chloroplasts results in massive proliferation of the inner envelope membrane and decreases susceptibility to salt and metal-induced oxidative stresses by reducing reactive oxygen species

(2014) Shuangxia Jin et al.   PLANT BIOTECHNOLOGY JOURNAL

Gene silencing in plants: A diversity of pathways

(2013) Angel Emilio Martínez de Alba et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Silencing the HaHR3 Gene by Transgenic Plant-mediated RNAi to Disrupt Helicoverpa armigera Development

(2013) Yehui Xiong et al.   International Journal of Biological Sciences

Oral Delivery of Bioencapsulated Proteins Across Blood–Brain and Blood–Retinal Barriers

(2013) Neha Kohli et al.   MOLECULAR THERAPY

Expression of Fungal Cutinase and Swollenin in Tobacco Chloroplasts Reveals Novel Enzyme Functions and/or Substrates

(2013) Dheeraj Verma et al.   PLoS One

Low Cost Tuberculosis Vaccine Antigens in Capsules: Expression in Chloroplasts, Bio-Encapsulation, Stability and Functional Evaluation In Vitro

(2013) Priya Saikumar Lakshmi et al.   PLoS One

RNA Interference towards the Potato Psyllid, Bactericera cockerelli, Is Induced in Plants Infected with Recombinant Tobacco mosaic virus (TMV)

(2013) Hada Wuriyanghan et al.   PLoS One

Silencing Abnormal Wing Disc Gene of the Asian Citrus Psyllid, Diaphorina citri Disrupts Adult Wing Development and Increases Nymph Mortality

(2013) Ibrahim El-Shesheny et al.   PLoS One

Release of Proteins from Intact Chloroplasts Induced by Reactive Oxygen Species during Biotic and Abiotic Stress

(2013) Kwang-Chul Kwon et al.   PLoS One

RNAi Silencing of the HaHMG-CoA Reductase Gene Inhibits Oviposition in the Helicoverpa armigera Cotton Bollworm

(2013) Zhijian Wang et al.   PLoS One

Oral delivery of human biopharmaceuticals, autoantigens and vaccine antigens bioencapsulated in plant cells

(2012) Kwang-Chul Kwon et al.   ADVANCED DRUG DELIVERY REVIEWS

Oral delivery of bioencapsulated exendin-4 expressed in chloroplasts lowers blood glucose level in mice and stimulates insulin secretion in beta-TC6 cells

(2012) Kwang-Chul Kwon et al.   PLANT BIOTECHNOLOGY JOURNAL

The Primary Transcriptome of Barley Chloroplasts: Numerous Noncoding RNAs and the Dominating Role of the Plastid-Encoded RNA Polymerase

(2012) P. Zhelyazkova et al.   PLANT CELL

Tobacco Rattle Virus Vector: A Rapid and Transient Means of Silencing Manduca sexta Genes by Plant Mediated RNA Interference

(2012) Pavan Kumar et al.   PLoS One

Improvement of Pest Resistance in Transgenic Tobacco Plants Expressing dsRNA of an Insect-Associated Gene EcR

(2012) Jin-Qi Zhu et al.   PLoS One

Plastid non-coding RNAs: emerging candidates for gene regulation

(2012) Amber M. Hotto et al.   TRENDS IN PLANT SCIENCE

Profiling of regulatory microRNA transcriptomes in various biological processes: a review

(2011) A. A. Shah et al.   JOURNAL OF APPLIED GENETICS

Protein-mediated protection as the predominant mechanism for defining processed mRNA termini in land plant chloroplasts

(2011) Petya Zhelyazkova et al.   NUCLEIC ACIDS RESEARCH

Short non-coding RNA fragments accumulating in chloroplasts: footprints of RNA binding proteins?

(2011) Hannes Ruwe et al.   NUCLEIC ACIDS RESEARCH

Characterization of plastid psb T sense and antisense RNAs

(2011) Ouafa Zghidi-Abouzid et al.   NUCLEIC ACIDS RESEARCH

Pinellia ternata agglutinin expression in chloroplasts confers broad spectrum resistance against aphid, whitefly, Lepidopteran insects, bacterial and viral pathogens

(2011) Shuangxia Jin et al.   PLANT BIOTECHNOLOGY JOURNAL

Metallothionein expression in chloroplasts enhances mercury accumulation and phytoremediation capability

(2011) Oscar N. Ruiz et al.   PLANT BIOTECHNOLOGY JOURNAL

Mutational analysis of Arabidopsis chloroplast polynucleotide phosphorylase reveals roles for both RNase PH core domains in polyadenylation, RNA 3′-end maturation and intron degradation

(2011) Arnaud Germain et al.   PLANT JOURNAL

Profiling of short RNAs during fleshy fruit development reveals stage-specific sRNAome expression patterns

(2011) Irina Mohorianu et al.   PLANT JOURNAL

Plastid biotechnology for crop production: present status and future perspectives

(2011) Jihong Liu Clarke et al.   PLANT MOLECULAR BIOLOGY

Knockdown of Midgut Genes by dsRNA-Transgenic Plant-Mediated RNA Interference in the Hemipteran Insect Nilaparvata lugens

(2011) Wenjun Zha et al.   PLoS One

Expression of Trichoderma reesei β-Mannanase in Tobacco Chloroplasts and Its Utilization in Lignocellulosic Woody Biomass Hydrolysis

(2011) Pankaj Agrawal et al.   PLoS One

Silencing of Aphid Genes by dsRNA Feeding from Plants

(2011) Marco Pitino et al.   PLoS One

Overexpression of a natural chloroplast-encoded antisense RNA in tobacco destabilizes 5S rRNA and retards plant growth

(2010) Amber M Hotto et al.   BMC PLANT BIOLOGY

Expression and characterization of antimicrobial peptides Retrocyclin-101 and Protegrin-1 in chloroplasts to control viral and bacterial infections

(2010) Seung-Bum Lee et al.   PLANT BIOTECHNOLOGY JOURNAL

Low-cost production of proinsulin in tobacco and lettuce chloroplasts for injectable or oral delivery of functional insulin and C-peptide

(2010) Diane Boyhan et al.   PLANT BIOTECHNOLOGY JOURNAL

Chloroplast-derived enzyme cocktails hydrolyse lignocellulosic biomass and release fermentable sugars

(2010) Dheeraj Verma et al.   PLANT BIOTECHNOLOGY JOURNAL

Release of Hormones from Conjugates: Chloroplast Expression of  -Glucosidase Results in Elevated Phytohormone Levels Associated with Significant Increase in Biomass and Protection from Aphids or Whiteflies Conferred by Sucrose Esters

(2010) S. Jin et al.   PLANT PHYSIOLOGY

The Role of Heterologous Chloroplast Sequence Elements in Transgene Integration and Expression

(2010) T. Ruhlman et al.   PLANT PHYSIOLOGY

Oral delivery of bioencapsulated coagulation factor IX prevents inhibitor formation and fatal anaphylaxis in hemophilia B mice

(2010) D. Verma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mirid Bug Outbreaks in Multiple Crops Correlated with Wide-Scale Adoption of Bt Cotton in China

(2010) Y. Lu et al.   SCIENCE

Cotton plants expressing CYP6AE14 double-stranded RNA show enhanced resistance to bollworms

(2010) Ying-Bo Mao et al.   TRANSGENIC RESEARCH

Ingested double-stranded RNAs can act as species-specific insecticides

(2009) Steven Whyard et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Chloroplast-derived vaccine antigens confer dual immunity against cholera and malaria by oral or injectable delivery

(2009) Abdoreza Davoodi-Semiromi et al.   PLANT BIOTECHNOLOGY JOURNAL

Developmental Control of a Lepidopteran Pest Spodoptera exigua by Ingestion of Bacteria Expressing dsRNA of a Non-Midgut Gene

(2009) Honggang Tian et al.   PLoS One

Transgenic plants as vital components of integrated pest management

(2009) Martine Kos et al.   TRENDS IN BIOTECHNOLOGY

Plant-made vaccine antigens and biopharmaceuticals

(2009) Henry Daniell et al.   TRENDS IN PLANT SCIENCE

Disruption of Spodoptera exigua larval development by silencing chitin synthase gene A with RNA interference

(2008) X. Chen et al.   BULLETIN OF ENTOMOLOGICAL RESEARCH

Effective Plague Vaccination via Oral Delivery of Plant Cells Expressing F1-V Antigens in Chloroplasts

(2008) P. A. Arlen et al.   INFECTION AND IMMUNITY

A protocol for expression of foreign genes in chloroplasts

(2008) Dheeraj Verma et al.   Nature Protocols

Exhaustion of the chloroplast protein synthesis capacity by massive expression of a highly stable protein antibiotic

(2008) Melanie Oey et al.   PLANT JOURNAL

Suppression of Cotton Bollworm in Multiple Crops in China in Areas with Bt Toxin-Containing Cotton

(2008) K.-M. Wu et al.   SCIENCE

How to cope with insect resistance to Bt toxins?

(2008) Alejandra Bravo et al.   TRENDS IN BIOTECHNOLOGY

Biological control and sustainable food production

(2007) J.S Bale et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES