Monoterpenoid indole alkaloids biosynthesis and its regulation in Catharanthus roseus: a literature review from genes to metabolites

Enhanced accumulation of catharanthine and vindoline in Catharanthus roseus hairy roots by overexpression of transcriptional factor ORCA2

(2016) Liu Dong Hui et al.   AFRICAN JOURNAL OF BIOTECHNOLOGY

A look inside an alkaloid multisite plant: the Catharanthus logistics

(2014) Vincent Courdavault et al.   CURRENT OPINION IN PLANT BIOLOGY

Making iridoids/secoiridoids and monoterpenoid indole alkaloids: progress on pathway elucidation

(2014) Vincenzo De Luca et al.   CURRENT OPINION IN PLANT BIOLOGY

High-Throughput Transcriptome Analysis of the Leafy Flower Transition of Catharanthus roseus Induced by Peanut Witches’-Broom Phytoplasma Infection

(2014) Li-Yu Daisy Liu et al.   PLANT AND CELL PHYSIOLOGY

Transcriptome Analysis of Catharanthus roseus for Gene Discovery and Expression Profiling

(2014) Mohit Verma et al.   PLoS One

The ORCA2 transcription factor plays a key role in regulation of the terpenoid indole alkaloid pathway

(2013) Chun Li et al.   BMC PLANT BIOLOGY

Characterization of two geraniol synthases from Valeriana officinalis and Lippia dulcis: Similar activity but difference in subcellular localization

(2013) Lemeng Dong et al.   METABOLIC ENGINEERING

Heteromeric and Homomeric Geranyl Diphosphate Synthases from Catharanthus roseus and Their Role in Monoterpene Indole Alkaloid Biosynthesis

(2013) Avanish Rai et al.   Molecular Plant

Bioinformatics challenges in de novo transcriptome assembly using short read sequences in the absence of a reference genome sequence

(2013) Elsa Góngora-Castillo et al.   NATURAL PRODUCT REPORTS

Investigation of the Chemomarkers Correlated with Flower Colour in Different Organs ofCatharanthus roseusUsing NMR-based Metabolomics

(2013) Qifang Pan et al.   PHYTOCHEMICAL ANALYSIS

CathaCyc, a Metabolic Pathway Database Built from Catharanthus roseus RNA-Seq Data

(2013) Alex Van Moerkercke et al.   PLANT AND CELL PHYSIOLOGY

Virus-induced gene silencing identifiesCatharanthus roseus7-deoxyloganic acid-7-hydroxylase, a step in iridoid and monoterpene indole alkaloid biosynthesis

(2013) Vonny Salim et al.   PLANT JOURNAL

A Pair of Tabersonine 16-Hydroxylases Initiates the Synthesis of Vindoline in an Organ-Dependent Manner in Catharanthus roseus

(2013) S. Besseau et al.   PLANT PHYSIOLOGY

Vacuolar Transport of the Medicinal Alkaloids from Catharanthus roseus Is Mediated by a Proton-Driven Antiport

(2013) I. Carqueijeiro et al.   PLANT PHYSIOLOGY

Development of efficient catharanthus roseus regeneration and transformation system using agrobacterium tumefaciens and hypocotyls as explants

(2012) Quan Wang et al.   BMC BIOTECHNOLOGY

CrMPK3, a mitogen activated protein kinase from Catharanthus roseus and its possible role in stress induced biosynthesis of monoterpenoid indole alkaloids

(2012) Susheel Raina et al.   BMC PLANT BIOLOGY

An alternative route to cyclic terpenes by reductive cyclization in iridoid biosynthesis

(2012) Fernando Geu-Flores et al.   NATURE

Characterization of the plastidial geraniol synthase from Madagascar periwinkle which initiates the monoterpenoid branch of the alkaloid pathway in internal phloem associated parenchyma

(2012) Andrew J. Simkin et al.   PHYTOCHEMISTRY

A single gene encodes isopentenyl diphosphate isomerase isoforms targeted to plastids, mitochondria and peroxisomes in Catharanthus roseus

(2012) Grégory Guirimand et al.   PLANT MOLECULAR BIOLOGY

Development of Transcriptomic Resources for Interrogating the Biosynthesis of Monoterpene Indole Alkaloids in Medicinal Plant Species

(2012) Elsa Góngora-Castillo et al.   PLoS One

In-depth proteome mining of culturedCatharanthus roseuscells identifies candidate proteins involved in the synthesis and transport of secondary metabolites

(2012) Antoine Champagne et al.   PROTEOMICS

Soybean transcription factor GmMYBZ2 represses catharanthine biosynthesis in hairy roots of Catharanthus roseus

(2011) Mei-Liang Zhou et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Overexpression of an apoplastic peroxidase gene CrPrx in transgenic hairy root lines of Catharanthus roseus

(2011) Monika Jaggi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Identification of phenolic compounds in isolated vacuoles of the medicinal plant Catharanthus roseus and their interaction with vacuolar class III peroxidase: an H2O2 affair?

(2011) Federico Ferreres et al.   JOURNAL OF EXPERIMENTAL BOTANY

Reengineering a Tryptophan Halogenase To Preferentially Chlorinate a Direct Alkaloid Precursor

(2011) Weslee S. Glenn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The basic helix-loop-helix transcription factor CrMYC2 controls the jasmonate-responsive expression of the ORCA genes that regulate alkaloid biosynthesis in Catharanthus roseus

(2011) Hongtao Zhang et al.   PLANT JOURNAL

The Transcription Factor CrWRKY1 Positively Regulates the Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus

(2011) N. Suttipanta et al.   PLANT PHYSIOLOGY

Cloning and characterization of two new Class III peroxidase genes from Catharanthus roseus

(2011) Santosh Kumar et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Jasmonate signaling involves the abscisic acid receptor PYL4 to regulate metabolic reprogramming in Arabidopsis and tobacco

(2011) P. Lackman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging trends in research on spatial and temporal organization of terpenoid indole alkaloid pathway in Catharanthus roseus: a literature update

(2011) Priyanka Verma et al.   PROTOPLASMA

Ectopic overexpression of vacuolar and apoplastic Catharanthus roseus peroxidases confers differential tolerance to salt and dehydration stress in transgenic tobacco

(2011) Santosh Kumar et al.   PROTOPLASMA

The subcellular organization of strictosidine biosynthesis in Catharanthus roseus epidermis highlights several trans-tonoplast translocations of intermediate metabolites

(2010) Grégory Guirimand et al.   FEBS Journal

Spatial organization of the vindoline biosynthetic pathway in Catharanthus roseus

(2010) Grégory Guirimand et al.   JOURNAL OF PLANT PHYSIOLOGY

The expression of 1-deoxy-d-xylulose synthase and geraniol-10-hydroxylase or anthranilate synthase increases terpenoid indole alkaloid accumulation in Catharanthus roseus hairy roots

(2010) Christie A.M. Peebles et al.   METABOLIC ENGINEERING

NMR-based metabolomic analysis of plants

(2010) Hye Kyong Kim et al.   Nature Protocols

Overexpression of G10H and ORCA3 in the hairy roots of Catharanthus roseus improves catharanthine production

(2010) Cui-Ting Wang et al.   PLANT CELL REPORTS

Metabolic Discrimination ofCatharanthus roseusCalli According to Their Relative Locations Using1H-NMR and Principal Component Analysis

(2009) Seung-Ok YANG et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Metabolic changes of salicylic acid-elicited Catharanthus roseus cell suspension cultures monitored by NMR-based metabolomics

(2009) Natali Rianika Mustafa et al.   BIOTECHNOLOGY LETTERS

Integrated omics approaches in plant systems biology

(2009) Atsushi Fukushima et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Flavonoid Glucosides from the Hairy Roots ofCatharanthus roseus

(2009) Ill-Min Chung et al.   JOURNAL OF NATURAL PRODUCTS

Improved accumulation of ajmalicine and tetrahydroalstonine in Catharanthus cells expressing an ABC transporter

(2009) Barbora Pomahačová et al.   JOURNAL OF PLANT PHYSIOLOGY

Metabolic reprogramming of periwinkle plant culture

(2009) Weerawat Runguphan et al.   Nature Chemical Biology

Biosynthesis of salicylic acid in fungus elicited Catharanthus roseus cells

(2009) Natali R. Mustafa et al.   PHYTOCHEMISTRY

A Chloroplastic UDP-Glucose Pyrophosphorylase from Arabidopsis Is the Committed Enzyme for the First Step of Sulfolipid Biosynthesis

(2009) Y. Okazaki et al.   PLANT CELL

Optimization of the transient transformation of Catharanthus roseus cells by particle bombardment and its application to the subcellular localization of hydroxymethylbutenyl 4-diphosphate synthase and geraniol 10-hydroxylase

(2009) Grégory Guirimand et al.   PLANT CELL REPORTS

Silencing of tryptamine biosynthesis for production of nonnatural alkaloids in plant culture

(2009) W. Runguphan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpression of 1-Deoxy-d-xylulose-5-phosphate reductoisomerase gene in chloroplast contributes to increment of isoprenoid production

(2008) Tomohisa Hasunuma et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Transcriptional response of the terpenoid indole alkaloid pathway to the overexpression of ORCA3 along with jasmonic acid elicitation of Catharanthus roseus hairy roots over time

(2008) Christie A.M. Peebles et al.   METABOLIC ENGINEERING

7-O-Methylated anthocyanidin glycosides from Catharanthus roseus

(2008) Kenjiro Toki et al.   PHYTOCHEMISTRY

The Leaf Epidermome of Catharanthus roseus Reveals Its Biochemical Specialization

(2008) J. Murata et al.   PLANT CELL