Ischemic injury promotes Keap1 nitration and disturbance of antioxidative responses in endothelial cells: a potential vasoprotective effect of melatonin

Targeting Nitrosative Stress for Neurovascular Protection: New Implications in Brain Diseases

(2012) Rong-Rong Tao et al.   CURRENT DRUG TARGETS

Signaling pathways activated by the phytochemical nordihydroguaiaretic acid contribute to a Keap1-independent regulation of Nrf2 stability: Role of glycogen synthase kinase-3

(2011) Ana I. Rojo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Melatonin treatment following stroke induction modulates l-arginine metabolism

(2011) Shiva M. Nair et al.   JOURNAL OF PINEAL RESEARCH

Regulation of the ischemia-induced autophagy-lysosome processes by nitrosative stress in endothelial cells

(2011) Feng Han et al.   JOURNAL OF PINEAL RESEARCH

Melatonin protects against transient focal cerebral ischemia in both reproductively active and estrogen-deficient female rats: the impact of circulating estrogen on its hormetic dose-response

(2011) Shih-Huang Tai et al.   JOURNAL OF PINEAL RESEARCH

Melatonin attenuates decrease of protein phosphatase 2A subunit B in ischemic brain injury

(2011) Phil-Ok Koh   JOURNAL OF PINEAL RESEARCH

Melatonin attenuates brain contusion-induced oxidative insult, inactivation of signal transducers and activators of transcription 1, and upregulation of suppressor of cytokine signaling-3 in rats

(2011) Ming Che Tsai et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as a natural ally against oxidative stress: a physicochemical examination

(2011) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

Evidence that membrane-bound G protein-coupled melatonin receptors MT1 and MT2 are not involved in the neuroprotective effects of melatonin in focal cerebral ischemia

(2011) Ulkan Kilic et al.   JOURNAL OF PINEAL RESEARCH

SCF/ -TrCP Promotes Glycogen Synthase Kinase 3-Dependent Degradation of the Nrf2 Transcription Factor in a Keap1-Independent Manner

(2011) P. Rada et al.   MOLECULAR AND CELLULAR BIOLOGY

The Neurovascular Link in Health and Disease: Molecular Mechanisms and Therapeutic Implications

(2011) Annelies Quaegebeur et al.   NEURON

Nitric oxide activates Nrf2 through S-nitrosylation of Keap1 in PC12 cells

(2011) Han-Cheon Um et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Carbon Monoxide–Activated Nrf2 Pathway Leads to Protection Against Permanent Focal Cerebral Ischemia

(2011) Bing Wang et al.   STROKE

The neurovascular unit, matrix proteases, and innate inflammation

(2010) Gregory J. Del Zoppo   Annals of the New York Academy of Sciences

Nuclear Matrix Protein (NRP/B) Modulates the Nuclear Factor (Erythroid-derived 2)-related 2 (NRF2)-dependent Oxidative Stress Response

(2010) Seyha Seng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physical and Functional Interaction of Sequestosome 1 with Keap1 Regulates the Keap1-Nrf2 Cell Defense Pathway

(2010) Ian M. Copple et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Melatonin ameliorates ischemic-like injury-evoked nitrosative stress: Involvement of HtrA2/PED pathways in endothelial cells

(2010) Feng Han et al.   JOURNAL OF PINEAL RESEARCH

Brain Endothelial Cell Death: Modes, Signaling Pathways, and Relevance to Neural Development, Homeostasis, and Disease

(2010) Maria Teresa Rizzo et al.   MOLECULAR NEUROBIOLOGY

The induction of reactive oxygen species and loss of mitochondrial Omi/HtrA2 is associated with S-nitrosoglutathione-induced apoptosis in human endothelial cells

(2010) Qi-bing Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

17 -Estradiol induces protein S-nitrosylation in the endothelium

(2009) S. Chakrabarti et al.   CARDIOVASCULAR RESEARCH

Reducing oxidative/nitrosative stress: a newly-discovered genre for melatonin

(2009) Russel J. Reiter et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Nrf2:INrf2 (Keap1) signaling in oxidative stress

(2009) James W. Kaspar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Biology of Vascular Malformations of the Brain

(2009) Gabrielle G. Leblanc et al.   STROKE

The Nrf2/ARE Pathway as a Potential Therapeutic Target in Neurodegenerative Disease

(2008) Marcus J. Calkins et al.   ANTIOXIDANTS & REDOX SIGNALING

Proteomic analysis of protein tyrosine nitration after ischemia reperfusion injury: Mitochondria as the major target

(2008) Bin Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Detection of protein S-nitrosylation with the biotin-switch technique

(2008) Michael T. Forrester et al.   FREE RADICAL BIOLOGY AND MEDICINE

Degradation of PEP-19, a calmodulin-binding protein, by calpain is implicated in neuronal cell death induced by intracellular Ca2+ overload

(2008) Y. Kanazawa et al.   NEUROSCIENCE

Accumulation of beta-amyloid in the brain microvessels accompanies increased hyperphosphorylated tau proteins following microsphere embolism in aged rats

(2008) F. Han et al.   NEUROSCIENCE

Keap1 modification and nuclear accumulation in response to S-nitrosocysteine

(2007) Barbara J. Buckley et al.   FREE RADICAL BIOLOGY AND MEDICINE

Carnosic acid, acatechol-typeelectrophilic compound, protects neurons bothin vitroandin vivothrough activation of the Keap1/Nrf2 pathway viaS-alkylation of targeted cysteines on Keap1

(2007) Takumi Satoh et al.   JOURNAL OF NEUROCHEMISTRY