Control of vascular smooth muscle function by Src-family kinases and reactive oxygen species in health and disease

Hypoxia-Inducible Factor-1α in Pulmonary Arterial Smooth Muscle Cells and Hypoxia-induced Pulmonary Hypertension

(2014) Kimberly A. Smith et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Selective regulation of cytoskeletal tension and cell–matrix adhesion by RhoA and Src

(2014) Harini Sreenivasappa et al.   Integrative Biology

A PLC 1-Dependent, Force-Sensitive Signaling Network in the Myogenic Constriction of Cerebral Arteries

(2014) A. L. Gonzales et al.   Science Signaling

Oxidative-Stress Biomarkers in Patients with Pulmonary Hypertension

(2014) Graziela S. Reis et al.   Pulmonary Circulation

cAMP attenuates the enhanced expression of Gi proteins and hyperproliferation of vascular smooth muscle cells from SHR: role of ROS and ROS-mediated signaling

(2013) Svetlana Gusan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Superoxide Generated at Mitochondrial Complex III Triggers Acute Responses to Hypoxia in the Pulmonary Circulation

(2013) Gregory B. Waypa et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Neprilysin Regulates Pulmonary Artery Smooth Muscle Cell Phenotype Through a Platelet-Derived Growth Factor Receptor–Dependent Mechanism

(2013) Vijaya Karoor et al.   HYPERTENSION

HIF and pulmonary vascular responses to hypoxia

(2013) Larissa A. Shimoda et al.   JOURNAL OF APPLIED PHYSIOLOGY

Oxidized High-Density Lipoprotein Induces the Proliferation and Migration of Vascular Smooth Muscle Cells by Promoting the Production of ROS

(2013) Yan Wang et al.   Journal of Atherosclerosis and Thrombosis

Hypoxic pulmonary vasoconstriction in the absence of pretone: essential role for intracellular Ca2+release

(2013) Michelle J. Connolly et al.   JOURNAL OF PHYSIOLOGY-LONDON

Reversible oxidation of PRL family protein-tyrosine phosphatases

(2013) Yosuke Funato et al.   METHODS

Drugs induced pulmonary arterial hypertension

(2013) Andrei Seferian et al.   PRESSE MEDICALE

Tyrosine Kinase Inhibitors in Pulmonary Arterial Hypertension: A Double-Edge Sword?

(2013) Laurent Godinas et al.   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

RhoA guanine exchange factor expression profile in arteries: evidence for a Rho kinase-dependent negative feedback in angiotensin II-dependent hypertension

(2012) Chrystelle Cario-Toumaniantz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Role of PKCα–p38MAPK–Giα axis in NADPH oxidase derived O2·--mediated activation of cPLA2 under U46619 stimulation in pulmonary artery smooth muscle cells

(2012) Sajal Chakraborti et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Novel Role of Proline-Rich Nonreceptor Tyrosine Kinase 2 in Vascular Wall Remodeling After Balloon Injury

(2012) Ravisekhar Gadepalli et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of Src Tyrosine Kinases in Experimental Pulmonary Hypertension

(2012) Soni Savai Pullamsetti et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Src tyrosine kinase is crucial for potassium channel function in human pulmonary arteries

(2012) C. Nagaraj et al.   EUROPEAN RESPIRATORY JOURNAL

Src modulates contractile vascular smooth muscle function via regulation of focal adhesions

(2012) Jianghong Min et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension

(2011) Roxane Paulin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Oxidative species increase arginase activity in endothelial cells through the RhoA/Rho kinase pathway

(2011) S Chandra et al.   BRITISH JOURNAL OF PHARMACOLOGY

15-Lipoxygenase-1-enhanced Src-Janus Kinase 2-Signal Transducer and Activator of Transcription 3 Stimulation and Monocyte Chemoattractant Protein-1 Expression Require Redox-sensitive Activation of Epidermal Growth Factor Receptor in Vascular Wall Remodeling

(2011) Nikhlesh K. Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role for miR-204 in human pulmonary arterial hypertension

(2011) Audrey Courboulin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NADPH Oxidase Pathway Is Involved in Aortic Contraction Induced by A3 Adenosine Receptor in Mice

(2011) M. S. El-Awady et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Hypoxia Enhances Platelet-derived Growth Factor Signaling in the Pulmonary Vasculature by Down-Regulation of Protein Tyrosine Phosphatases

(2010) Henrik ten Freyhaus et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Redox Regulation of Protein Kinases as a Modulator of Vascular Function

(2010) Greg A. Knock et al.   ANTIOXIDANTS & REDOX SIGNALING

Superoxide differentially controls pulmonary and systemic vascular tone through multiple signalling pathways

(2010) Vladimir A. Snetkov et al.   CARDIOVASCULAR RESEARCH

Nitric oxide, oxidative stress and inflammation in pulmonary arterial hypertension

(2010) Patrick Crosswhite et al.   JOURNAL OF HYPERTENSION

The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure

(2010) Christophe Guilluy et al.   NATURE MEDICINE

Updated Clinical Classification of Pulmonary Hypertension

(2009) Gérald Simonneau et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Role of src-family kinases in hypoxic vasoconstriction of rat pulmonary artery

(2008) Greg A. Knock et al.   CARDIOVASCULAR RESEARCH

Redox-based regulation of signal transduction: Principles, pitfalls, and promises

(2008) Yvonne M.W. Janssen-Heininger et al.   FREE RADICAL BIOLOGY AND MEDICINE

Superoxide constricts rat pulmonary arteries via Rho-kinase-mediated Ca2+ sensitization

(2008) Greg A. Knock et al.   FREE RADICAL BIOLOGY AND MEDICINE

PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility

(2008) Yangmi Lim et al.   JOURNAL OF CELL BIOLOGY