Muscle-specific kinase (MuSK) autoantibodies suppress the MuSK pathway and ACh receptor retention at the mouse neuromuscular junction

Antibodies against low-density lipoprotein receptor–related protein 4 induce myasthenia gravis

(2013) Chengyong Shen et al.   JOURNAL OF CLINICAL INVESTIGATION

Pyridostigmine but not 3,4-diaminopyridine exacerbates ACh receptor loss and myasthenia induced in mice by muscle-specific kinase autoantibody

(2013) Marco Morsch et al.   JOURNAL OF PHYSIOLOGY-LONDON

Sequence of Age-Associated Changes to the Mouse Neuromuscular Junction and the Protective Effects of Voluntary Exercise

(2013) Anson Cheng et al.   PLoS One

MuSK Myasthenia Gravis IgG4 Disrupts the Interaction of LRP4 with MuSK but Both IgG4 and IgG1-3 Can Disperse Preformed Agrin-Independent AChR Clusters

(2013) Inga Koneczny et al.   PLoS One

MuSK IgG4 autoantibodies cause myasthenia gravis by inhibiting binding between MuSK and Lrp4

(2013) M. G. Huijbers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and superorganization of acetylcholine receptor-rapsyn complexes

(2013) B. Zuber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Muscle-specific kinase myasthenia gravis IgG4 autoantibodies cause severe neuromuscular junction dysfunction in mice

(2012) Rinse Klooster et al.   BRAIN

Muscle specific kinase autoantibodies cause synaptic failure through progressive wastage of postsynaptic acetylcholine receptors

(2012) Marco Morsch et al.   EXPERIMENTAL NEUROLOGY

Passive and active immunization models of MuSK-Ab positive myasthenia: Electrophysiological evidence for pre and postsynaptic defects

(2012) Stuart Viegas et al.   EXPERIMENTAL NEUROLOGY

Neuregulin-1 potentiates agrin-induced acetylcholine receptor clustering through muscle-specific kinase phosphorylation

(2012) S. T. Ngo et al.   JOURNAL OF CELL SCIENCE

Rapsyn mediates subsynaptic anchoring of PKA type I and stabilisation of acetylcholine receptor in vivo

(2012) K.-R. Choi et al.   JOURNAL OF CELL SCIENCE

Divalent and monovalent autoantibodies cause dysfunction of MuSK by distinct mechanisms in a rabbit model of myasthenia gravis

(2012) Shuuichi Mori et al.   JOURNAL OF NEUROIMMUNOLOGY

Antibodies against Muscle-Specific Kinase Impair Both Presynaptic and Postsynaptic Functions in a Murine Model of Myasthenia Gravis

(2011) Shuuichi Mori et al.   AMERICAN JOURNAL OF PATHOLOGY

Muscle-selective synaptic disassembly and reorganization in MuSK antibody positive MG mice

(2011) Anna Rostedt Punga et al.   EXPERIMENTAL NEUROLOGY

Neuregulin/ErbB regulate neuromuscular junction development by phosphorylation of α-dystrobrevin

(2011) Nadine Schmidt et al.   JOURNAL OF CELL BIOLOGY

Anti-MuSK autoantibodies block binding of collagen Q to MuSK

(2011) Y. Kawakami et al.   NEUROLOGY

Autoantibodies to low-density lipoprotein receptor-related protein 4 in myasthenia gravis

(2010) Osamu Higuchi et al.   ANNALS OF NEUROLOGY

Patient autoantibodies deplete postsynaptic muscle-specific kinase leading to disassembly of the ACh receptor scaffold and myasthenia gravis in mice

(2010) R. N. Cole et al.   JOURNAL OF PHYSIOLOGY-LONDON

The Cytoplasmic Adaptor Protein Dok7 Activates the Receptor Tyrosine Kinase MuSK via Dimerization

(2010) Elisa Bergamin et al.   MOLECULAR CELL

Pre- and postsynaptic neuromuscular junction abnormalities in musk myasthenia

(2010) Erik H. Niks et al.   MUSCLE & NERVE

Myosin Va cooperates with PKA RI  to mediate maintenance of the endplate in vivo

(2010) I. V. Roder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reporting ethical matters inThe Journal of Physiology: standards and advice

(2009) Gordon B. Drummond   JOURNAL OF PHYSIOLOGY-LONDON

The Roles of the Dystrophin-Associated Glycoprotein Complex at the Synapse

(2009) Gonneke S. K. Pilgram et al.   MOLECULAR NEUROBIOLOGY

Rapsyn interacts with the muscle acetylcholine receptor via α-helical domains in the α, β, and ε subunit intracellular loops

(2009) Y. Lee et al.   NEUROSCIENCE

Anti-MuSK patient antibodies disrupt the mouse neuromuscular junction

(2008) Rebecca N. Cole et al.   ANNALS OF NEUROLOGY

Lrp4 Is a Receptor for Agrin and Forms a Complex with MuSK

(2008) Natalie Kim et al.   CELL

An Ankyrin-Based Mechanism for Functional Organization of Dystrophin and Dystroglycan

(2008) Gai Ayalon et al.   CELL

Identification of a Motif in the Acetylcholine Receptor   Subunit Whose Phosphorylation Regulates Rapsyn Association and Postsynaptic Receptor Localization

(2008) L. S. Borges et al.   JOURNAL OF NEUROSCIENCE

Muscle-Specific Receptor Tyrosine Kinase Endocytosis in Acetylcholine Receptor Clustering in Response to Agrin

(2008) D. Zhu et al.   JOURNAL OF NEUROSCIENCE

LRP4 Serves as a Coreceptor of Agrin

(2008) Bin Zhang et al.   NEURON