Article
Agronomy
Aleksandra Figarska, Olga Witkowska-Pilaszewicz
Summary: The immunology of pregnancy focuses on the immune responses of a mother and her fetus to each other. Recent research has shed light on the complex immunological processes that allow the developing fetus to survive without being rejected by the mother's immune system. Horses are a valuable animal model for pregnancy immunology research due to their unique anatomy and physiology.
Article
Hematology
Shuting Wei, Wei Liu, Yu Qi, Yifan Guo, Shuping Zhang, Li Wang, Taifeng Zhuang, Na Zhang, Sijin Liu
Summary: The study found disordered maternal iron homeostasis in women who had early spontaneous abortions, with increased serum iron and hepcidin levels, and decreased serum ERFE levels. The elevated serum hepcidin and ERFE ratio (HE ratio) showed potential as a diagnostic marker for identifying adverse pregnancy outcomes.
BRITISH JOURNAL OF HAEMATOLOGY
(2021)
Article
Biology
Nathan Deming, Sarah Steer, Jesse Hernandez, Frank Dinenno, Jennifer Richards
Summary: This study demonstrates for the first time that carbohydrate ingestion may have a protective effect on cognitive function during long duration passive heat stress. Furthermore, this protection is associated with preserved internal carotid artery blood flow and glucose delivery to the brain.
JOURNAL OF THERMAL BIOLOGY
(2023)
Review
Pharmacology & Pharmacy
Anaelle Monfort, Ema Ferreira, Gregoire Leclair, Gregory Anton Lodygensky
Summary: Cannabis use during pregnancy and breastfeeding can have negative effects on birth outcomes and lacks robust pharmacokinetics data. Studies on the effects of cannabis on brain development should be accompanied by pharmacokinetics studies to assess correlations. More research is needed to understand the safety of cannabis use during pregnancy and breastfeeding.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Physiology
Daniel Hammarstrom, Sjur J. ofsteng, Nicolai B. Jacobsen, Krister B. Flobergseter, Bent R. Ronnestad, Stian Ellefsen
Summary: This study describes the ribosome biogenesis during resistance training and its relationship with training volume and muscle growth. The researchers found that ribosomes accumulate in the initial phase of training and the rate of accumulation predicts muscle hypertrophy. Additionally, ribosome biogenesis is associated with UBF protein levels.
Article
Physiology
Andre L. Teixeira, Jordan B. B. Lee, Massimo Nardone, Jamie F. F. Burr, Philip J. J. Millar
Summary: The sympathetic nervous system plays a crucial role in cardiovascular regulation, particularly in response to acute stress. The relationship between renal and leg vasoconstriction at rest or during sympathetic stressors is not yet known. This study aimed to investigate the relationships between muscle sympathetic nerve activity (MSNA), leg vascular conductance (LVC), and renal vascular conductance (RVC) in young healthy adults, both at rest and during laboratory-based stressors. The findings revealed differential control of regional sympathetic vasoconstriction at rest and during stress in young healthy humans.
JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Chunjiang Cai, Ying Ren, Jianhua Cao, Shengya Fang, Leying Zhang, Ling Yang
Summary: This study found that early pregnancy induces changes in the I kappa B family, which are closely related to maternal peripheral tolerance and pregnancy establishment in sheep. This suggests that the regulation of the I kappa B family may be favorable for maternal hepatic functions during pregnancy.
Article
Nutrition & Dietetics
Kiwamu Noshiro, Takeshi Umazume, Rifumi Hattori, Soromon Kataoka, Takashi Yamada, Hidemichi Watari
Summary: This study found that hemoglobin levels during the first trimester of pregnancy are efficient predictors of anemia occurring during the third trimester. In a longitudinal assessment of 231 healthy Japanese women, it was observed that women with lower red blood cell count, hemoglobin, hematocrit, and ferritin levels during the first trimester were more likely to develop anemia in the third trimester.
Article
Biochemistry & Molecular Biology
Maria Fernanda Garces, Julieth Daniela Buell-Acosta, Edith Angel-Mueller, Arturo Jose Parada-Banos, Jaidy Acosta-Alvarez, Harold Felipe Saavedra-Lopez, Roberto Franco-Vega, Luis Miguel Maldonado-Acosta, Franklin Escobar-Cordoba, Keydy Vasquez-Romero, Ezequiel Lacunza, Sofia Alexandra Caminos-Cepeda, Ruben Nogueiras, Carlos Dieguez, Ariel Ivan Ruiz-Parra, Jorge Eduardo Caminos
Summary: This study found that the Ghrelin/LEAP-2 ratio reaches its peak after mid-pregnancy in humans and rats, and it is associated with weight gain during pregnancy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Neurosciences
Ana Luiza C. Sayegh, Jui-Lin Fan, Mathew Dawes, Julian F. R. Paton, James P. Fisher
Summary: The study found that central respiratory and sympathetic chemoreflex sensitivities are increased in hypertensive patients, suggesting that these reflexes may play a role in the development of hypertension.
JOURNAL OF PHYSIOLOGY-LONDON
(2023)
Review
Sport Sciences
Polina M. Krassovskaia, Alec B. Chaves, Joseph A. Houmard, Nicholas T. Broskey
Summary: Low birth weight is associated with adult cardiovascular disease mortality, highlighting the importance of prenatal lifestyle interventions. However, the direct impact of lifestyle interventions such as exercise on offspring metabolism and the underlying mechanisms remain unclear. Further research is needed to address these gaps and guide future studies.
INTERNATIONAL JOURNAL OF SPORTS MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jitka Starekova, Scott K. Nagle, Mark L. Schiebler, Scott B. Reeder, Venkata N. Meduri
Summary: This retrospective observational study described the clinical experience with Ferumoxytol-enhanced magnetic resonance angiography (Fe-MRA) in pregnant women with suspected pulmonary embolism (PE). The study found that Fe-MRA is a radiation- and gadolinium-free alternative for diagnosing PE during pregnancy.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Review
Developmental Biology
Jing Zhao, Wenjie Wang, Ling Zhang, Jia Zhang, Roger Sturmey, Jin Zhang
Summary: Early mammalian embryos exhibit dynamic metabolism to support changing cell fates during development. Metabolic pathways play crucial roles in cellular energetic demands, cell signalling, gene regulation, cell proliferation, and differentiation. Recent advances in metabolomics and computational analysis have deepened our understanding of the important role of dynamic metabolism in early mammalian embryogenesis.
Article
Physiology
Didier Collard, Lennart van de Velde, Valerie E. Stegehuis, Ronak Delewi, Marcel A. M. Beijk, IJsbrand A. J. Zijlstra, Robbert J. de Winter, Liffert Vogt, Bert-Jan H. van den Born
Summary: Renal sympathetic innervation is crucial in regulating renal and systemic hemodynamics and serves as a target for pharmacological and catheter-based therapies. This study investigated the effect of static handgrip exercise on renal hemodynamics and intraglomerular pressure in humans. The findings suggest that measuring renal arterial pressure and flow velocity during handgrip exercise can help identify individuals with different levels of sympathetic control over renal perfusion.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
(2023)
Article
Environmental Sciences
Jiyeon Ham, Whasun Lim, Gwonhwa Song
Summary: Ethalfluralin, a dinitroaniline-type herbicide, inhibits the viability, proliferation, and migration of porcine luminal epithelial and trophectoderm cells by disrupting calcium homeostasis and impairing mitochondrial function. It also activates endoplasmic reticulum stress signals and autophagy pathways, while suppressing the PI3K/AKT signaling pathway.
ENVIRONMENTAL POLLUTION
(2022)
Article
Peripheral Vascular Disease
Mark B. Badrov, Sun Young Park, Jeung-Ki Yoo, Michinari Hieda, Yoshiyuki Okada, Sara S. Jarvis, Abigail S. Stickford, Stuart A. Best, David B. Nelson, Qi Fu
Article
Geriatrics & Gerontology
Graeme Carrick-Ranson, Francis G. Spinale, Paul S. Bhella, Satyam Sarma, Shigeki Shibata, Naoki Fujimoto, Jeffrey L. Hastings, Benjamin D. Levine
EXPERIMENTAL GERONTOLOGY
(2019)
Article
Cardiac & Cardiovascular Systems
Qi Fu, Shigeki Shibata, Jeffrey L. Hastings, Steven H. Platts, Douglas M. Hamilton, Michael W. Bungo, Michael B. Stenger, Christine Ribeiro, Beverley Adams-Huet, Benjamin D. Levine
Article
Physiology
Shigehiko Ogoh, Kazuya Suzuki, Takuro Washio, Kazuki Tamiya, Shotaro Saito, Tom G. Bailey, Shigeki Shibata, Go Ito, Tadayoshi Miyamoto
EXPERIMENTAL PHYSIOLOGY
(2019)
Article
Dentistry, Oral Surgery & Medicine
Soichiro Kawase, Yoshiyuki Okada, Kazushige Isono, Hitoshi Iwasaki, Takashi Kuno, Kohei Matsumura, Yiwen Fu, Yorikazu Harada, Tadashi Ogasawara
Article
Physiology
Spencer C. Cushen, Marc L. Sprouse, Alexandra Blessing, Jie Sun, Sara S. Jarvis, Yoshiyuki Okada, Qi Fu, Steven A. Romero, Nicole R. Phillips, Styliani Goulopoulou
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
(2020)
Article
Peripheral Vascular Disease
Mark B. Badrov, Yoshiyuki Okada, Jeung-Ki Yoo, Wanpen Vongpatanasin, J. Kevin Shoemaker, Benjamin D. Levine, Qi Fu
Article
Neurosciences
Yoshiyuki Okada, M. Melyn Galbreath, Sara S. Jarvis, Shigeki Shibata, Wanpen Vongpatanasin, Benjamin D. Levine, Qi Fu
JOURNAL OF PHYSIOLOGY-LONDON
(2020)
Article
Multidisciplinary Sciences
Toshifumi Muneyasu, Harutoyo Hirano, Akira Furui, Zu Soh, Ryuji Nakamura, Noboru Saeki, Yoshiyuki Okada, Masashi Kawamoto, Masao Yoshizumi, Atsuo Yoshino, Takafumi Sasaoka, Shigeto Yamawaki, Toshio Tsuji
Summary: This study aimed to investigate the features of peripheral arterial stiffness to determine whether it inherits the features of muscle sympathetic nerve activity (MSNA) for non-invasive evaluation. Results showed that peripheral arterial stiffness beta exhibits similar features to MSNA, making it an effective non-invasive substitute for MSNA measurement.
SCIENTIFIC REPORTS
(2021)
Article
Clinical Neurology
Chueh-Lung Hwang, Kazunobu Okazaki, Shigeki Shibata, Yu-Lun Liu, Qi Fu
Summary: This study investigated the effects of the menstrual cycle on muscle sympathetic nerve activity burst amplitude distribution during an orthostatic challenge in young women. The results showed that the mean and median values of relative burst amplitude increased from supine to upright position, regardless of menstrual cycle phases. However, the skewness and kurtosis of burst amplitude distribution varied between the early follicular phase and mid-luteal phase.
CLINICAL AUTONOMIC RESEARCH
(2021)
Article
Nutrition & Dietetics
Shinya Matsushima, Minoru Yoshida, Hitoshi Yokoyama, Yosuke Watanabe, Hidetaka Onodera, Haruaki Wakatake, Hiroki Saito, Masahiko Kimura, Shigeki Shibata
Summary: The study showed that critically ill patients in the ICU with higher protein intake had better muscle strength at discharge and recovered to independent walking faster compared to those with lower protein intake.
Article
Education, Special
Y. Oda, K. Yoshida, R. Kawano, T. Yoshinaka, A. Oda, T. Takahashi, K. Oue, A. Mukai, M. Irifune, Y. Okada
Summary: This study compared the cardiovascular effects of oral antipsychotic medication on patients with intellectual disabilities during dental treatment under intravenous sedation. The results suggest that antipsychotic medication may not have clinically significant adverse effects on cardiovascular fluctuations in this population.
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH
(2022)
Article
Dentistry, Oral Surgery & Medicine
Yuki Oda, Keita Yoshida, Chiaki Furutani, Atsuko Wakita, Yoko Hama, Miwa Miyauchi, Yoshiyuki Okada
Summary: This case report describes a female patient with Joubert syndrome who successfully underwent dental treatment through physical behavior adjustment and oxygenation, avoiding the risk of apnea attacks.
SPECIAL CARE IN DENTISTRY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Yuki Oda, Chiaki Furutani, Yuika Mizota, Atsuko Wakita, Sumiyo Mimura, Takuya Kihara, Masaru Ohara, Yoshiyuki Okada, Mitsugi Okada, Hiroki Nikawa
JOURNAL OF APPLIED ORAL SCIENCE
(2019)
Article
Physiology
Zachary J. Schlader, Yoshiyuki Okada, Stuart A. Best, Qi Fu, Craig G. Crandall
PHYSIOLOGICAL REPORTS
(2019)