Copper-dependent regulation of NMDA receptors by cellular prion protein: implications for neurodegenerative disorders

Effect of N-methyl-D-aspartate (NMDA) receptor antagonists on α-synuclein-evoked neuronal nitric oxide synthase activation in the rat brain

(2014) Agata Adamczyk et al.   Pharmacological Reports

A  neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptors

(2012) H. You et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Depressive-like behaviour of mice lacking cellular prion protein

(2011) Vinicius M. Gadotti et al.   BEHAVIOURAL BRAIN RESEARCH

PrPC interacts with potassium channel tetramerization domain containing 1 (KCTD1) protein through the PrP51-136 region containing octapeptide repeats

(2011) Tao Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Amyloid β peptide oligomers directly activate NMDA receptors

(2011) Laura Texidó et al.   CELL CALCIUM

Molecular basis of NMDA receptor functional diversity

(2011) Pierre Paoletti   EUROPEAN JOURNAL OF NEUROSCIENCE

Drug delivery strategies for Alzheimer's disease treatment

(2011) Antonio Di Stefano et al.   Expert Opinion on Drug Delivery

Regulation of NMDA receptors by the tyrosine kinase Fyn

(2011) Catherine H. Trepanier et al.   FEBS Journal

Unification of the Copper(I) Binding Affinities of the Metallo-chaperones Atx1, Atox1, and Related Proteins

(2011) Zhiguang Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of the CaMKII/NMDA Receptor Complex in the Maintenance of Synaptic Strength

(2011) M. Sanhueza et al.   JOURNAL OF NEUROSCIENCE

Alzheimer's Disease Brain-Derived Amyloid- -Mediated Inhibition of LTP In Vivo Is Prevented by Immunotargeting Cellular Prion Protein

(2011) A. E. Barry et al.   JOURNAL OF NEUROSCIENCE

Cellular Prion Protein Protects from Inflammatory and Neuropathic Pain

(2011) Vinicius M Gadotti et al.   Molecular Pain

Threshold for epileptiform activity is elevated in prion knockout mice

(2011) S. Ratté et al.   NEUROSCIENCE

Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

(2011) Darragh B. Freir et al.   Nature Communications

Ligand-specific deactivation time course of GluN1/GluN2D NMDA receptors

(2011) Katie M. Vance et al.   Nature Communications

The Synucleins Are a Family of Redox-Active Copper Binding Proteins

(2010) Paul Davies et al.   BIOCHEMISTRY

Pharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signalling

(2010) Wei Hu et al.   BRAIN

Prion protein and Aβ-related synaptic toxicity impairment

(2010) Anna Maria Calella et al.   EMBO Molecular Medicine

Metabotropic glutamate receptors transduce signals for neurite outgrowth after binding of the prion protein to laminin γ1 chain

(2010) Flavio H. Beraldo et al.   FASEB JOURNAL

Role of α7 Nicotinic Acetylcholine Receptor in Calcium Signaling Induced by Prion Protein Interaction with Stress-inducible Protein 1

(2010) Flavio H. Beraldo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Triheteromeric NR1/NR2A/NR2B Receptors Constitute the MajorN-Methyl-d-aspartate Receptor Population in Adult Hippocampal Synapses

(2010) Claudia Rauner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Memory Impairment in Transgenic Alzheimer Mice Requires Cellular Prion Protein

(2010) D. A. Gimbel et al.   JOURNAL OF NEUROSCIENCE

Excitatory Glycine Responses of CNS Myelin Mediated by NR1/NR3 "NMDA" Receptor Subunits

(2010) J. C. Pina-Crespo et al.   JOURNAL OF NEUROSCIENCE

Ionic mechanisms of action of prion protein fragment PrP(106-126) in rat basal forebrain neurons

(2010) Kwai Alier et al.   JOURNAL OF NEUROSCIENCE RESEARCH

New Insights into the Not-So-New NR3 Subunits of N-Methyl-D-aspartate Receptor: Localization, Structure, and Function

(2010) C.-M. Low et al.   MOLECULAR PHARMACOLOGY

The prion protein as a receptor for amyloid-β

(2010) Helmut W. Kessels et al.   NATURE

Axonal prion protein is required for peripheral myelin maintenance

(2010) Juliane Bremer et al.   NATURE NEUROSCIENCE

Getting a Grip on Prions: Oligomers, Amyloids, and Pathological Membrane Interactions

(2009) Byron Caughey et al.   Annual Review of Biochemistry

The multi-layered regulation of copper translocating P-type ATPases

(2009) Nicholas A. Veldhuis et al.   BIOMETALS

RNAi for the Treatment of Prion Disease: A Window for Intervention in Neurodegeneration?

(2009) Melanie White et al.   CNS & Neurological Disorders-Drug Targets

Effects of Copper on T-Type Ca2+ Channels in Mouse Spermatogenic Cells

(2009) Liang Lu et al.   JOURNAL OF MEMBRANE BIOLOGY

Mg2+ Imparts NMDA Receptor Subtype Selectivity to the Alzheimer's Drug Memantine

(2009) S. E. Kotermanski et al.   JOURNAL OF NEUROSCIENCE

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

(2009) Juha Laurén et al.   NATURE

Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake

(2009) Shaomin Li et al.   NEURON

Regulation of GABAA and Glutamate Receptor Expression, Synaptic Facilitation and Long-Term Potentiation in the Hippocampus of Prion Mutant Mice

(2009) Alejandra Rangel et al.   PLoS One

Absence of the Cellular Prion Protein Exacerbates and Prolongs Neuroinflammation in Experimental Autoimmune Encephalomyelitis

(2008) Shigeki Tsutsui et al.   AMERICAN JOURNAL OF PATHOLOGY

Molecular Mechanisms of Prion Pathogenesis

(2008) Adriano Aguzzi et al.   Annual Review of Pathology-Mechanisms of Disease

Control of Excitatory Synaptic Transmission by C-terminal Src Kinase

(2008) Jindong Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prion protein attenuates excitotoxicity by inhibiting NMDA receptors

(2008) Houman Khosravani et al.   JOURNAL OF CELL BIOLOGY

NMDA receptors in clinical neurology: excitatory times ahead

(2008) Lorraine V Kalia et al.   LANCET NEUROLOGY

Treatment of inflammatory and neuropathic pain by uncoupling Src from the NMDA receptor complex

(2008) Xue Jun Liu et al.   NATURE MEDICINE

Distinct gating modes determine the biphasic relaxation of NMDA receptor currents

(2008) Wei Zhang et al.   NATURE NEUROSCIENCE

A nomenclature for ligand-gated ion channels

(2008) Graham L. Collingridge et al.   NEUROPHARMACOLOGY

Allosteric modulation of NMDA receptor via elevation of brain glycine and d-serine: The therapeutic potentials for schizophrenia

(2008) Charles R. Yang et al.   PHARMACOLOGY & THERAPEUTICS

Physiology of the Prion Protein

(2008) Rafael Linden et al.   PHYSIOLOGICAL REVIEWS

Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease

(2008) M. D. White et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed inXenopus laevisoocytes

(2007) Philip E. Chen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Characterization of Copper Interactions with Alzheimer Amyloid β Peptides

(2003) Craig S. Atwood et al.   JOURNAL OF NEUROCHEMISTRY