SYMPOSIUM REVIEW: The role of the KATPchannel in glucose homeostasis in health and disease: more than meets the islet

New Uses for Old Drugs: Neonatal Diabetes and Sulphonylureas

(2010) Frances M. Ashcroft   Cell Metabolism

Molecular mechanisms underlying nutrient-stimulated incretin secretion

(2010) Helen E. Parker et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Secondary Consequences of β Cell Inexcitability: Identification and Prevention in a Murine Model of KATP-Induced Neonatal Diabetes Mellitus

(2009) Maria Sara Remedi et al.   Cell Metabolism

Coexpression of the Type 2 Diabetes Susceptibility Gene Variants KCNJ11 E23K and ABCC8 S1369A Alter the ATP and Sulfonylurea Sensitivities of the ATP-Sensitive K+ Channel

(2009) K. S.C. Hamming et al.   DIABETES

Kir6.2 Variant E23K Increases ATP-Sensitive K+ Channel Activity and Is Associated With Impaired Insulin Release and Enhanced Insulin Sensitivity in Adults With Normal Glucose Tolerance

(2009) D. T. Villareal et al.   DIABETES

Regulation of insulin secretion: a matter of phase control and amplitude modulation

(2009) J. C. Henquin   DIABETOLOGIA

Adjacent mutations in the gating loop of Kir6.2 produce neonatal diabetes and hyperinsulinism

(2009) Kenju Shimomura et al.   EMBO Molecular Medicine

Sar1-GTPase-dependent ER exit of KATP channels revealed by a mutation causing congenital hyperinsulinism

(2009) Tarvinder K. Taneja et al.   HUMAN MOLECULAR GENETICS

Sulphonylurea therapy improves cognition in a patient with the V59M KCNJ11 mutation

(2008) A. S. Slingerland et al.   DIABETIC MEDICINE

Update of mutations in the genes encoding the pancreatic beta-cell KATPchannel subunits Kir6.2 (KCNJ11) and sulfonylurea receptor 1 (ABCC8) in diabetes mellitus and hyperinsulinism

(2008) Sarah E. Flanagan et al.   HUMAN MUTATION

Destabilization of ATP-sensitive Potassium Channel Activity by NovelKCNJ11Mutations Identified in Congenital Hyperinsulinism

(2008) Yu-Wen Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clinical characteristics and biochemical mechanisms of congenital hyperinsulinism associated with dominant KATP channel mutations

(2008) Sara E. Pinney et al.   JOURNAL OF CLINICAL INVESTIGATION

The G53D Mutation in Kir6.2 (KCNJ11) Is Associated with Neonatal Diabetes and Motor Dysfunction in Adulthood that Is Improved with Sulfonylurea Therapy

(2007) Joseph C. Koster et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM