Article
Obstetrics & Gynecology
Beatrix Thompson, Parker Holzer, Harvey Kliman
Summary: There are approximately 5 million pregnancies per year in the USA, with 1 million ending in miscarriage and over 20,000 ending in stillbirth. As many as 50% of these losses are unexplained. The study aimed to evaluate the effect of expanding placental pathology diagnostic categories in examining previously unexplained losses and found that dysmorphic chorionic villi and small placenta were common pathologic features associated with these losses.
REPRODUCTIVE SCIENCES
(2023)
Review
Agriculture, Dairy & Animal Science
S. G. Umana Sedo, C. B. Winder, D. L. Renaud
Summary: Calf mortality is an important indicator of animal health and welfare on dairy farms, but challenges in calculation and definition hinder the comparison of mortality rates. Monitoring factors associated with calf mortality is crucial, as discrepancies in evaluating these factors still exist. This review discusses the lack of reliable data and standardization in defining calf mortality, as well as current strategies for monitoring and preventing it.
JOURNAL OF DAIRY SCIENCE
(2023)
Review
Medicine, General & Internal
Anastasija Arechvo, Despoina A. Nikolaidi, Maria M. Gil, Valeria Rolle, Argyro Syngelaki, Ranjit Akolekar, Kypros H. Nicolaides
Summary: This study found that the independent predictor of stillbirth is higher for black women compared to other racial groups, with the risk being about two times higher than that for white women. This suggests that closer surveillance should be provided for black women.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Dana A. Muin, Martina Kollmann, Jasmin Blatterer, Gregor Hoermann, Peter W. Husslein, Ingrid Lafer, Erwin Petek, Thomas Schwarzbraun
Summary: Investigating cardio-pathogenic variants in singleton fetuses after unexplained intrauterine fetal death revealed that most male fetuses died at a median gestational age of 34 weeks, with a high proportion of variants of uncertain significance in cardio-specific genes.
SCIENTIFIC REPORTS
(2021)
Review
Medicine, General & Internal
Tiechao Ruan, Yan Yue, Wenting Lu, Ruixi Zhou, Tao Xiong, Yin Jiang, Junjie Ying, Jun Tang, Jing Shi, Hua Wang, Guoguang Xiao, Jinhui Li, Yi Qu, Dezhi Mu
Summary: Exposure to low ambient temperature during pregnancy increases the risk of adverse birth outcomes, including preterm birth, low birth weight, and stillbirth. Pregnant women in late pregnancy and those exposed to extremely low temperatures are more likely to experience preterm births. Pregnant women living in medium or hot areas and Asians and Blacks are more susceptible to the effects of low ambient temperature than those in cold areas and Caucasians.
CHINESE MEDICAL JOURNAL
(2023)
Review
Medicine, General & Internal
Yingying Tian, Xiuhua Yang
Summary: Uterine artery Doppler can predict significant vascular events during pregnancy, and predicting pregnancy complications in advance can reduce harm to mothers and neonates.
FRONTIERS IN MEDICINE
(2022)
Article
Obstetrics & Gynecology
H. Valgeirsdottir, T. Kunovac Kallak, I. Sundstrom Poromaa, M. Jonsson, N. Roos, L. Lindstrom, A-K Wikstrom
Summary: A nationwide register-based cohort study in Sweden found that women with polycystic ovary syndrome (PCOS) have an increased risk of stillbirth, particularly in late pregnancy. Compared to women without PCOS, women with PCOS had a 50% higher risk of stillbirth. However, women with PCOS and a severe hyperandrogenic profile did not show a stronger association with stillbirth compared to those without this profile.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2021)
Article
Endocrinology & Metabolism
Maheswaran Dhanasekaran, Sneha Mohan, Dana Erickson, Pankaj Shah, Linda Szymanski, Vella Adrian, Aoife M. Egan
Summary: This study evaluated the occurrence of diabetic ketoacidosis (DKA) in pregnant women at our hospital and identified the associated clinical risk factors. The study found that DKA was associated with a high rate of maternofetal morbidity and fetal loss. Maternal social stressors and suboptimal glycemic control were commonly found. Prenatal education strategies for women with diabetes mellitus should prioritize the prevention of DKA.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Review
Obstetrics & Gynecology
Ana Bonell, Cherie Part, Uduak Okomo, Rebecca Cole, Shakoor Hajat, Sari Kovats, Amanda N. N. Sferruzzi-Perri, Jane E. E. Hirst
Summary: Exposure to extreme heat during pregnancy increases the risk of stillbirth. Majority studies show an association between heat and stillbirth risk, with recent research in low- to middle-income countries and tropical settings confirming that all populations are at risk. Both short-term and whole-pregnancy heat exposure contribute to the risk. The mechanisms behind this association involve placental and embryonic or fetal impacts, including epigenetic changes, alteration in imprinted genes, congenital abnormalities, and reduction in placental blood flow and function.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Obstetrics & Gynecology
Sukainah Al Khalaf, Karolina Kublickiene, Marius Kublickas, Ali S. Khashan, Alexander E. P. Heazell
Summary: The study found that women with a history of stillbirth in the first two pregnancies have an increased risk of stillbirth or other adverse outcomes in the third pregnancy. Additional surveillance is recommended for these women.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2023)
Review
Biochemistry & Molecular Biology
Anna Kajdy, Dorota Sys, Jan Modzelewski, Joanna Boguslawska, Aneta Cymbaluk-Ploska, Ewa Kwiatkowska, Magdalena Bednarek-Jedrzejek, Dariusz Borowski, Katarzyna Stefanska, Michal Rabijewski, Arkadiusz Baran, Andrzej Torbe, Stepan Feduniw, Sebastian Kwiatkowski
Summary: During pregnancy, the placenta naturally undergoes an aging process, but an abnormally accelerated and premature placental aging may lead to health issues. Placental senescence is associated with obstetric complications such as abnormal fetal growth, preeclampsia, preterm birth, and stillbirth. However, there is limited evidence on the role of placental aging in late small for gestational age (SGA), fetal growth restriction (FGR), and stillbirth. Future research should follow guidelines for planning and reporting and include clear differentiation between early and late SGA and FGR, and only include stillbirths with no other known cause.
Article
Public, Environmental & Occupational Health
Kaitlyn K. Stanhope, Jeff R. Temple, Carla Bann, Corette B. Parker, Donald Dudley, Carol J. R. Hogue
Summary: The majority of health research uses a deductive approach to measure stressful life events, but this study used an inductive process to identify the self-identified most stressful life events in women who experienced perinatal loss. Stillbirth was most commonly identified as the most stressful event, followed by loss by death of someone other than a child. Childhood maltreatment was associated with a lower risk of identifying perinatal loss as the most stressful event.
SOCIAL SCIENCE & MEDICINE
(2021)
Review
Public, Environmental & Occupational Health
Shashi B. Singh, Bijaya K. Padhi, Aravind P. Gandhi, Pallavi Lohani, Nisha Kumari, Geetu Singh, Prakasini Satapathy, Keerti Bhusan Pradhan, Sarvesh Rustagi, Alaa Hamza Hermis, Arkadiusz Dziedzic, Ranjit Sah
Summary: This study aims to estimate the global burden of stillbirths among pregnant women with COVID-19 vaccination. The systematic review and meta-analysis found a low prevalence of stillbirths among pregnant women vaccinated against COVID-19 infection.
TRAVEL MEDICINE AND INFECTIOUS DISEASE
(2023)
Article
Peripheral Vascular Disease
Brooke Armistead, Leena Kadam, Emily Siegwald, Fergus P. McCarthy, John C. Kingdom, Hamid-Reza Kohan-Ghadr, Sascha Drewlo
Summary: Preeclampsia is a severe hypertensive disorder of pregnancy caused by placental villi pathology leading to widespread maternal endothelial dysfunction. Modulating trophoblast differentiation pathway through PPAR gamma-GCM1 axis may reduce excessive sFLT1 production and improve clinical outcomes. Pharmacological manipulation of PPAR gamma activity shows potential to rescue the antiangiogenic state of preeclampsia.
Article
Public, Environmental & Occupational Health
Sha Huang, Jia Yi Hee, Yuxun Oswald Zhang, Ruofan Gongye, Siyu Zou, Kun Tang
Summary: This study found that pregnancy loss, especially spontaneous and induced abortions, is associated with an increased risk of COPD among Chinese women. However, a single pregnancy has a protective effect.
FRONTIERS IN PUBLIC HEALTH
(2022)
