Rapid asymmetric reduction of ethyl 4-chloro-3-oxobutanoate using a thermostabilized mutant of ketoreductase ChKRED20

Upscale production of ethyl (S)-4-chloro-3-hydroxybutanoate by using carbonyl reductase coupled with glucose dehydrogenase in aqueous-organic solvent system

(2014) Zhi-Qiang Liu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Identification of ketone reductase ChKRED20 from the genome of Chryseobacterium sp. CA49 for highly efficient anti-Prelog reduction of 3,5-bis(trifluoromethyl)acetophenone

(2014) Yan Liu et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Characterization of a robust anti-Prelog short-chain dehydrogenase/reductase ChKRED20 from Chryseobacterium sp. CA49

(2014) Tuo-Xian Tang et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

(2014) Marco Biasini et al.   NUCLEIC ACIDS RESEARCH

Multi-Enzymatic Biosynthesis of Chiral β-Hydroxy Nitriles through Co-Expression of Oxidoreductase and Halohydrin Dehalogenase

(2013) Shao-Yun Chen et al.   ADVANCED SYNTHESIS & CATALYSIS

Characterization of a newly synthesized carbonyl reductase and construction of a biocatalytic process for the synthesis of ethyl (S)-4-chloro-3-hydroxybutanoate with high space-time yield

(2013) Zhong-Yu You et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Biochemical and structural characterization of recombinant short-chain NAD(H)-dependent dehydrogenase/reductase from Sulfolobus acidocaldarius highly enantioselective on diaryl diketone benzil

(2012) Angela Pennacchio et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Multiple amino acid substitutions significantly improve the thermostability of feruloyl esterase A from Aspergillus niger

(2012) Shuai-Bing Zhang et al.   BIORESOURCE TECHNOLOGY

Modifying enzyme activity and selectivity by immobilization

(2012) Rafael C. Rodrigues et al.   CHEMICAL SOCIETY REVIEWS

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

Coupling Chemical Modification and Immobilization to Improve the Catalytic Performance of Enzymes

(2011) Rafael C. Rodrigues et al.   ADVANCED SYNTHESIS & CATALYSIS

Industrial biotransformations in the synthesis of building blocks leading to enantiopure drugs

(2011) D. Muñoz Solano et al.   BIORESOURCE TECHNOLOGY

Biocatalytic ketone reduction: A green and efficient access to enantiopure alcohols

(2011) Yan Ni et al.   BIOTECHNOLOGY ADVANCES

Enzymatic reductions for the chemist

(2011) Frank Hollmann et al.   GREEN CHEMISTRY

A review—biosynthesis of optically pure ethyl (S)-4-chloro-3-hydroxybutanoate ester: recent advances and future perspectives

(2010) Qi Ye et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Asymmetric synthesis of (S)-ethyl-4-chloro-3-hydroxy butanoate using a Saccharomyces cerevisiae reductase: Enantioselectivity and enzyme–substrate docking studies

(2010) Jihye Jung et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Three amino acid changes contribute markedly to the thermostability of β-glucosidase BglC from Thermobifida fusca

(2010) Xiao-Qiong Pei et al.   BIORESOURCE TECHNOLOGY

Practical chiral alcohol manufacture using ketoreductases

(2010) Gjalt W Huisman et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Uses and production of chiral 3-hydroxy-γ-butyrolactones and structurally related chemicals

(2009) Sang-Hyun Lee et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Characterization of temperature dependent and substrate-binding cleft movements in Bacillus circulans family 11 xylanase: A molecular dynamics investigation

(2009) Davi Serradella Vieira et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

A green-by-design biocatalytic process for atorvastatin intermediate

(2009) Steven K. Ma et al.   GREEN CHEMISTRY

Development of a Practical Biocatalytic Process for (R)-2-Methylpentanol

(2009) Owen W. Gooding et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Highly Enantioselective Reduction of a Small Heterocyclic Ketone: Biocatalytic Reduction of Tetrahydrothiophene-3-one to the Corresponding (R)-Alcohol

(2009) Jack Liang et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Enhancement of thermostability of fungal deglycating enzymes by directed evolution

(2008) Kozo Hirokawa et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The SWISS-MODEL Repository and associated resources

(2008) F. Kiefer et al.   NUCLEIC ACIDS RESEARCH

Preparative Asymmetric Synthesis of 4,4-Dimethoxytetrahydro-2H-pyran-3-ol with a Ketone Reductase and in Situ Cofactor Recycling using Glucose Dehydrogenase

(2008) Birgit Kosjek et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Synthesis of chiral pharmaceutical intermediates by biocatalysis

(2007) Ramesh N. Patel   COORDINATION CHEMISTRY REVIEWS