Direct acute tubular damage contributes to Shigatoxin-mediated kidney failure

Distinct Renal Pathology and a Chemotactic Phenotype after Enterohemorrhagic Escherichia coli Shiga Toxins in Non-Human Primate Models of Hemolytic Uremic Syndrome

(2013) Deborah J. Stearns-Kurosawa et al.   AMERICAN JOURNAL OF PATHOLOGY

Ouabain Protects against Shiga Toxin-Triggered Apoptosis by Reversing the Imbalance between Bax and Bcl-xL

(2013) I. Burlaka et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sulfatides are required for renal adaptation to chronic metabolic acidosis

(2013) P. Stettner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Globosides but Not Isoglobosides Can Impact the Development of Invariant NKT Cells and Their Interaction with Dendritic Cells

(2012) S. Porubsky et al.   JOURNAL OF IMMUNOLOGY

Renal and neurological involvement in typical Shiga toxin-associated HUS

(2012) Howard Trachtman et al.   Nature Reviews Nephrology

Best supportive care and therapeutic plasma exchange with or without eculizumab in Shiga-toxin-producing E. coli O104:H4 induced haemolytic–uraemic syndrome: an analysis of the German STEC-HUS registry

(2012) Jan T. Kielstein et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104:H4 induced haemolytic uraemic syndrome: case-control study

(2012) J. Menne et al.   BMJ-British Medical Journal

Differential Response of the Human Renal Proximal Tubular Epithelial Cell Line HK-2 to Shiga Toxin Types 1 and 2

(2011) Erin K. Lentz et al.   INFECTION AND IMMUNITY

Alternative Pathway Activation of Complement by Shiga Toxin Promotes Exuberant C3a Formation That Triggers Microvascular Thrombosis

(2011) M. Morigi et al.   JOURNAL OF IMMUNOLOGY

Shiga toxin glycosphingolipid receptors in microvascular and macrovascular endothelial cells: differential association with membrane lipid raft microdomains

(2011) Josefine Betz et al.   JOURNAL OF LIPID RESEARCH

Treatment of severe neurological deficits with IgG depletion through immunoadsorption in patients with Escherichia coli O104:H4-associated haemolytic uraemic syndrome: a prospective trial

(2011) Andreas Greinacher et al.   LANCET

Characterisation of the Escherichia coli strain associated with an outbreak of haemolytic uraemic syndrome in Germany, 2011: a microbiological study

(2011) Martina Bielaszewska et al.   LANCET INFECTIOUS DISEASES

Eculizumab in Severe Shiga-Toxin–Associated HUS

(2011) Anne-Laure Lapeyraque et al.   NEW ENGLAND JOURNAL OF MEDICINE

Origins of theE. coliStrain Causing an Outbreak of Hemolytic–Uremic Syndrome in Germany

(2011) David A. Rasko et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epidemic Profile of Shiga-Toxin–ProducingEscherichia coliO104:H4 Outbreak in Germany

(2011) Christina Frank et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prospective Genomic Characterization of the German Enterohemorrhagic Escherichia coli O104:H4 Outbreak by Rapid Next Generation Sequencing Technology

(2011) Alexander Mellmann et al.   PLoS One

Induced Domain Formation in Endocytic Invagination, Lipid Sorting, and Scission

(2010) Ludger Johannes et al.   CELL

Escherichia coli Shiga Toxin Mechanisms of Action in Renal Disease

(2010) Tom G. Obrig   Toxins

Shiga Toxin 2 Targets the Murine Renal Collecting Duct Epithelium

(2009) M. A. Psotka et al.   INFECTION AND IMMUNITY

Eculizumab for Atypical Hemolytic–Uremic Syndrome

(2009) Jens Nürnberger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Atypical Hemolytic–Uremic Syndrome

(2009) Marina Noris et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mouse Model of Hemolytic-Uremic Syndrome Caused by Endotoxin-Free Shiga Toxin 2 (Stx2) and Protection from Lethal Outcome by Anti-Stx2 Antibody

(2008) K. A. D. Sauter et al.   INFECTION AND IMMUNITY