Through the glass darkly: intraepithelial neoplasia, top-down differentiation, and the road to ovarian cancer

Cervical Squamocolumnar Junction–specific Markers Define Distinct, Clinically Relevant Subsets of Low-grade Squamous Intraepithelial Lesions

(2013) Michael Herfs et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Early transformative changes in normal ovarian surface epithelium induced by oxidative stress require Akt upregulation, DNA damage and epithelial–stromal interaction

(2013) Shelby M. King et al.   CARCINOGENESIS

Prophylactic salpingectomy in premenopausal low-risk women for ovarian cancer: Primum non nocere

(2013) Michele Morelli et al.   GYNECOLOGIC ONCOLOGY

Long term follow up of BRCA1 and BRCA2 mutation carriers with unsuspected neoplasia identified at risk reducing salpingo-oophorectomy

(2013) C.B. Powell et al.   GYNECOLOGIC ONCOLOGY

Ovarian surface epithelium as a source of ovarian cancers: Unwarranted speculation or evidence-based hypothesis?

(2013) Nelly Auersperg   GYNECOLOGIC ONCOLOGY

Ovarian cancer risk factors by tumor dominance, a surrogate for cell of origin

(2013) Joanne Kotsopoulos et al.   INTERNATIONAL JOURNAL OF CANCER

Differential Expression of p-ERM, a Marker of Cell Polarity, in Benign and Neoplastic Oviductal Epithelium

(2013) Gang Ning et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

Overdiagnosis and Overtreatment in Cancer

(2013) Laura J. Esserman et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche

(2013) Andrea Flesken-Nikitin et al.   NATURE

Human papillomavirus (HPV) vaccine implementation in low and middle-income countries (LMICs): Health system experiences and prospects

(2013) Jannah Wigle et al.   VACCINE

A Simulation Model to Predict the Impact of Prophylactic Surgery and Screening on the Life Expectancy of BRCA1 and BRCA2 Mutation Carriers

(2012) B. M. Sigal et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The Oviduct and Ovarian Cancer

(2012) CHRISTOPHER P. CRUM et al.   CLINICAL OBSTETRICS AND GYNECOLOGY

Cellular Origin of Barrett's Esophagus: Controversy and Therapeutic Implications

(2012) Wa Xian et al.   GASTROENTEROLOGY

Frequency of Serous Tubal Intraepithelial Carcinoma in Various Gynecologic Malignancies

(2012) Shangguo Tang et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

A novel blueprint for ‘top down’ differentiation defines the cervical squamocolumnar junction during development, reproductive life, and neoplasia

(2012) Michael Herfs et al.   JOURNAL OF PATHOLOGY

Assessment of symptomatic women for early diagnosis of ovarian cancer: results from the prospective DOvE pilot project

(2012) Lucy Gilbert et al.   LANCET ONCOLOGY

Digital quantification of precursor frequency in the fallopian tube and its significance

(2012) Jonathan G Bijron et al.   MODERN PATHOLOGY

High-grade serous ovarian cancer arises from fallopian tube in a mouse model

(2012) J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer

(2012) M. Herfs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Residual Embryonic Cells as Precursors of a Barrett's-like Metaplasia

(2011) Xia Wang et al.   CELL

PAX2-null secretory cell outgrowths in the oviduct and their relationship to pelvic serous cancer

(2011) Charles M Quick et al.   MODERN PATHOLOGY

Molecular and functional characteristics of ovarian surface epithelial cells transformed by KrasG12D and loss of Pten in a mouse model in vivo

(2011) L K Mullany et al.   ONCOGENE

The Origin and Pathogenesis of Epithelial Ovarian Cancer: A Proposed Unifying Theory

(2010) Robert J. Kurman et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Are All Pelvic (Nonuterine) Serous Carcinomas of Tubal Origin?

(2010) Christopher G. Przybycin et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Cancer Statistics, 2010

(2010) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

HPV16 E2 Is an Immediate Early Marker of Viral Infection, Preceding E7 Expression in Precursor Structures of Cervical Carcinoma

(2010) Y. Xue et al.   CANCER RESEARCH

A comparison of human papillomavirus testing of clinician-collected and self-collected samples during follow-up after screen-and-treat

(2010) Sylvia Taylor et al.   INTERNATIONAL JOURNAL OF CANCER

Cancer survival in Australia, Canada, Denmark, Norway, Sweden, and the UK, 1995–2007 (the International Cancer Benchmarking Partnership): an analysis of population-based cancer registry data

(2010) MP Coleman et al.   LANCET

Differentiated vulvar intraepithelial neoplasia contains Tp53 mutations and is genetically linked to vulvar squamous cell carcinoma

(2010) Alvaro P Pinto et al.   MODERN PATHOLOGY

Genetic Analysis of the Early Natural History of Epithelial Ovarian Carcinoma

(2010) Bhavana Pothuri et al.   PLoS One

Precursor Lesions of High-Grade Serous Ovarian Carcinoma: Morphological and Molecular Characteristics

(2010) Amy L. Gross et al.   Journal of Oncology

Serous Tubal Intraepithelial Carcinoma and the Dominant Ovarian Mass

(2009) Michael H. Roh et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes

(2009) Rumi Sasaki et al.   CARCINOGENESIS

Acquisition of a second mutation of the Tp53 alleles immediately precedes epithelial morphological transformation in ovarian tumorigenicity

(2009) Kathy Q. Cai et al.   GYNECOLOGIC ONCOLOGY

Serous Carcinogenesis in the Fallopian Tube

(2009) Elke Jarboe et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY

The Li–Fraumeni syndrome (LFS): a model for the initiation of p53 signatures in the distal Fallopian tube

(2009) Wa Xian et al.   JOURNAL OF PATHOLOGY

Assessing Lead Time of Selected Ovarian Cancer Biomarkers: A Nested Case–Control Study

(2009) Garnet L. Anderson et al.   JNCI-Journal of the National Cancer Institute

Primary ex vivo cultures of human fallopian tube epithelium as a model for serous ovarian carcinogenesis

(2009) K Levanon et al.   ONCOGENE

PTEN Expression in Endometrial Biopsies as a Marker of Progression to Endometrial Carcinoma

(2008) J. V. Lacey et al.   CANCER RESEARCH

Risk-reduction surgery in BRCA mutation carriers in a Spanish population: adherence and results

(2008) Pedro Pérez Segura et al.   Clinical & Translational Oncology

Does the fimbria have an embryologic origin distinct from that of the rest of the fallopian tube?

(2008) Leslie A. Garrett et al.   FERTILITY AND STERILITY

Chromosomal instability in fallopian tube precursor lesions of serous carcinoma and frequent monoclonality of synchronous ovarian and fallopian tube mucosal serous carcinoma

(2008) Shannon Salvador et al.   GYNECOLOGIC ONCOLOGY

A candidate precursor to pelvic serous cancer (p53 signature) and its prevalence in ovaries and fallopian tubes from women with BRCA mutations

(2008) Ann K. Folkins et al.   GYNECOLOGIC ONCOLOGY

Serous Tubal Intraepithelial Carcinoma: Its Potential Role in Primary Peritoneal Serous Carcinoma and Serous Cancer Prevention

(2008) Joseph W. Carlson et al.   JOURNAL OF CLINICAL ONCOLOGY