Podocyte loss involves MDM2-driven mitotic catastrophe

p53-Independent Roles of MDM2 in NF-κB Signaling: Implications for Cancer Therapy, Wound Healing, and Autoimmune Diseases

(2015) Dana Thomasova et al.   NEOPLASIA

Podocyte Mitosis - A Catastrophe

(2012) L. Lasagni et al.   CURRENT MOLECULAR MEDICINE

Plasma leakage through glomerular basement membrane ruptures triggers the proliferation of parietal epithelial cells and crescent formation in non-inflammatory glomerular injury

(2012) Mi Ryu et al.   JOURNAL OF PATHOLOGY

Histones from Dying Renal Cells Aggravate Kidney Injury via TLR2 and TLR4

(2012) R. Allam et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

MDM2 (murine double minute-2) links inflammation and tubular cell healing during acute kidney injury in mice

(2012) Shrikant R. Mulay et al.   KIDNEY INTERNATIONAL

Four danger response programs determine glomerular and tubulointerstitial kidney pathology

(2012) Hans-Joachim Anders   Organogenesis

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

(2011) Markus Gödel et al.   JOURNAL OF CLINICAL INVESTIGATION

mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

(2011) Ken Inoki et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumour necrosis factor-α drives Alport glomerulosclerosis in mice by promoting podocyte apoptosis

(2011) Mi Ryu et al.   JOURNAL OF PATHOLOGY

Parietal Epithelial Cells Participate in the Formation of Sclerotic Lesions in Focal Segmental Glomerulosclerosis

(2011) B. Smeets et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renal microenvironments and macrophage phenotypes determine progression or resolution of renal inflammation and fibrosis

(2011) Hans-Joachim Anders et al.   KIDNEY INTERNATIONAL

Reversible cell-cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signaling

(2011) Marina Shkreli et al.   NATURE MEDICINE

Focal Segmental Glomerulosclerosis

(2011) Vivette D. D'Agati et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mechanisms of Tubulointerstitial Fibrosis

(2010) M. Zeisberg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Glomerular Epithelial Stem Cells: The Good, The Bad, and The Ugly

(2010) L. Lasagni et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NF- B in Renal Inflammation

(2010) A. B. Sanz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Bacterial CpG-DNA accelerates Alport glomerulosclerosis by inducing an M1 macrophage phenotype and tumor necrosis factor-α-mediated podocyte loss

(2010) Mi Ryu et al.   KIDNEY INTERNATIONAL

Adriamycin nephropathy: A model of focal segmental glomerulosclerosis

(2010) VINCENT WS LEE et al.   NEPHROLOGY

Progressive glomerulosclerosis in type 2 diabetes is associated with renal histone H3K9 and H3K23 acetylation, H3K4 dimethylation and phosphorylation at serine 10

(2010) Sufyan G. Sayyed et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Notch Activation Differentially Regulates Renal Progenitors Proliferation and Differentiation Toward the Podocyte Lineage in Glomerular Disorders

(2010) Laura Lasagni et al.   STEM CELLS

Renal Progenitor Cells Contribute to Hyperplastic Lesions of Podocytopathies and Crescentic Glomerulonephritis

(2009) B. Smeets et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Rapamycin Attenuates the Severity of Murine Adriamycin Nephropathy

(2008) Sing Leung Lui et al.   AMERICAN JOURNAL OF NEPHROLOGY

Late Onset of Ccl2 Blockade with the Spiegelmer mNOX-E36–3′PEG Prevents Glomerulosclerosis and Improves Glomerular Filtration Rate in db/db Mice

(2008) Volha Ninichuk et al.   AMERICAN JOURNAL OF PATHOLOGY

Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy

(2008) Sanjeev Shangary et al.   Annual Review of Pharmacology and Toxicology

Death through a tragedy: mitotic catastrophe

(2008) H Vakifahmetoglu et al.   CELL DEATH AND DIFFERENTIATION

Viral 5′-triphosphate RNA and non-CpG DNA aggravate autoimmunity and lupus nephritis via distinct TLR-independent immune responses

(2008) Ramanjaneyulu Allam et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regeneration of Glomerular Podocytes by Human Renal Progenitors

(2008) E. Ronconi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Recruitment of Podocytes from Glomerular Parietal Epithelial Cells

(2008) D. Appel et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Notch pathway in podocytes plays a role in the development of glomerular disease

(2008) Thiruvur Niranjan et al.   NATURE MEDICINE

The genetics of the p53 pathway, apoptosis and cancer therapy

(2008) Alexei Vazquez et al.   NATURE REVIEWS DRUG DISCOVERY

Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition

(2008) S. Shangary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA