Primary cilia and coordination of receptor tyrosine kinase (RTK) signalling

Orientation of Primary Cilia of Articular Chondrocytes in Three-Dimensional Space

(2011) Cornelia E. Farnum et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Polycystins, focal adhesions and extracellular matrix interactions

(2011) Iain A. Drummond   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The ciliary pocket: a once-forgotten membrane domain at the base of cilia

(2011) Rania Ghossoub et al.   BIOLOGY OF THE CELL

Intraflagellar transport proteins in ciliogenesis of photoreceptor cells

(2011) Tina Sedmak et al.   BIOLOGY OF THE CELL

A Role for the Primary Cilium in Notch Signaling and Epidermal Differentiation during Skin Development

(2011) Ellen J. Ezratty et al.   CELL

p27 as Jekyll and Hyde: Regulation of cell cycle and cell motility

(2011) Michelle D. Larrea et al.   CELL CYCLE

Cilia and cell cycle re-entry

(2011) Sehyun Kim et al.   CELL CYCLE

Cilia in the nervous system: linking cilia function and neurodevelopmental disorders

(2011) Ji E Lee et al.   CURRENT OPINION IN NEUROLOGY

The Activated Targets of mTOR Signaling Pathway Are Characteristic for PDGFRA Mutant and Wild-type Rather Than KIT Mutant GISTs

(2011) Zoltán Sápi et al.   DIAGNOSTIC MOLECULAR PATHOLOGY

Targeting p27Kip1protein: its relevance in the therapy of human cancer

(2011) Adriana Borriello et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia

(2011) J. B. Wallingford et al.   GENES & DEVELOPMENT

Fibroblast growth factors: from molecular evolution to roles in development, metabolism and disease

(2011) N. Itoh et al.   JOURNAL OF BIOCHEMISTRY

MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis

(2011) Corey L. Williams et al.   JOURNAL OF CELL BIOLOGY

TOR kinase complexes and cell migration

(2011) Lunhua Liu et al.   JOURNAL OF CELL BIOLOGY

EB1 and EB3 promote cilia biogenesis by several centrosome-related mechanisms

(2011) J. M. Schroder et al.   JOURNAL OF CELL SCIENCE

C14ORF179 encoding IFT43 is mutated in Sensenbrenner syndrome

(2011) H. H. Arts et al.   JOURNAL OF MEDICAL GENETICS

Loss of Primary Cilia Upregulates Renal Hypertrophic Signaling and Promotes Cystogenesis

(2011) P. D. Bell et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

IFT20 is required for opsin trafficking and photoreceptor outer segment development

(2011) Brian T. Keady et al.   MOLECULAR BIOLOGY OF THE CELL

Ciliary transition zone activation of phosphorylated Tctex-1 controls ciliary resorption, S-phase entry and fate of neural progenitors

(2011) Aiqun Li et al.   NATURE CELL BIOLOGY

Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry

(2011) Sehyun Kim et al.   NATURE CELL BIOLOGY

Ciliopathies

(2011) Friedhelm Hildebrandt et al.   NEW ENGLAND JOURNAL OF MEDICINE

The long and winding road to rational treatment of cancer associated with LKB1/AMPK/TSC/mTORC1 signaling

(2011) W van Veelen et al.   ONCOGENE

Ciliopathies: an expanding disease spectrum

(2011) Aoife M. Waters et al.   PEDIATRIC NEPHROLOGY

A Variant of Fibroblast Growth Factor Receptor 2 (Fgfr2) Regulates Left-Right Asymmetry in Zebrafish

(2011) Da-Wei Liu et al.   PLoS One

Canopy1, a positive feedback regulator of FGF signaling, controls progenitor cell clustering during Kupffer's vesicle organogenesis

(2011) T. Matsui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Receptor tyrosine kinase–G-protein-coupled receptor signalling platforms: out of the shadow?

(2011) Nigel J. Pyne et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Cranioectodermal Dysplasia, Sensenbrenner Syndrome, Is a Ciliopathy Caused by Mutations in the IFT122 Gene

(2010) Joanna Walczak-Sztulpa et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Trafficking to the Ciliary Membrane: How to Get Across the Periciliary Diffusion Barrier?

(2010) Maxence V. Nachury et al.   Annual Review of Cell and Developmental Biology

Mechanical loading modulates chondrocyte primary cilia incidence and length

(2010) Susan R McGlashan et al.   CELL BIOLOGY INTERNATIONAL

Neuronal ciliary signaling in homeostasis and disease

(2010) Jill A. Green et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Directional Cell Migration and Chemotaxis in Wound Healing Response to PDGF-AA are Coordinated by the Primary Cilium in Fibroblasts

(2010) Linda Schneider et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The ciliary membrane

(2010) Rajat Rohatgi et al.   CURRENT OPINION IN CELL BIOLOGY

FGF signalling: diverse roles during early vertebrate embryogenesis

(2010) K. Dorey et al.   DEVELOPMENT

Pitchfork Regulates Primary Cilia Disassembly and Left-Right Asymmetry

(2010) Doris Kinzel et al.   DEVELOPMENTAL CELL

CEP290 tethers flagellar transition zone microtubules to the membrane and regulates flagellar protein content

(2010) Branch Craige et al.   JOURNAL OF CELL BIOLOGY

The primary cilium at a glance

(2010) P. Satir et al.   JOURNAL OF CELL SCIENCE

The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia

(2010) A. Molla-Herman et al.   JOURNAL OF CELL SCIENCE

Primary cilia organization reflects polarity in the growth plate and implies loss of polarity and mosaicism in osteochondroma

(2010) Carlos E de Andrea et al.   LABORATORY INVESTIGATION

EGF receptor activation by GPCRs: An universal pathway reveals different versions

(2010) Claus Liebmann   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

(2010) Katrin Düvel et al.   MOLECULAR CELL

A comprehensive map of the mTOR signaling network

(2010) Etienne Caron et al.   Molecular Systems Biology

Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-β2 and RanGTP

(2010) John F. Dishinger et al.   NATURE CELL BIOLOGY

Primary cilia regulate mTORC1 activity and cell size through Lkb1

(2010) Christopher Boehlke et al.   NATURE CELL BIOLOGY

The primary cilium: a signalling centre during vertebrate development

(2010) Sarah C. Goetz et al.   NATURE REVIEWS GENETICS

RPGR: Role in the photoreceptor cilium, human retinal disease, and gene therapy

(2010) Jutta Hosch et al.   OPHTHALMIC GENETICS

Setdb2 restricts dorsal organizer territory and regulates left-right asymmetry through suppressing fgf8 activity

(2010) P.-F. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Septin Diffusion Barrier at the Base of the Primary Cilium Maintains Ciliary Membrane Protein Distribution

(2010) Q. Hu et al.   SCIENCE

Fibroblast Growth Factor Receptor Signaling Crosstalk in Skeletogenesis

(2010) H. Miraoui et al.   Science Signaling

Akt-RSK-S6 Kinase Signaling Networks Activated by Oncogenic Receptor Tyrosine Kinases

(2010) A. Moritz et al.   Science Signaling

p21WAF1/CIP1and cancer: A shifting paradigm?

(2009) Andrei L. Gartel   BIOFACTORS

The Vertebrate Primary Cilium in Development, Homeostasis, and Disease

(2009) Jantje M. Gerdes et al.   CELL

Characterization of Primary Cilia in Human Airway Smooth Muscle Cells

(2009) Jun Wu et al.   CHEST

Centriole Age Underlies Asynchronous Primary Cilium Growth in Mammalian Cells

(2009) Charles T. Anderson et al.   CURRENT BIOLOGY

Fgf4 is required for left–right patterning of visceral organs in zebrafish

(2009) Hajime Yamauchi et al.   DEVELOPMENTAL BIOLOGY

EGF receptor in relation to tumor development: molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors

(2009) Kenji Takeuchi et al.   FEBS Journal

Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

(2009) Seongjin Seo et al.   HUMAN MOLECULAR GENETICS

Articular chondrocytes express connexin 43 hemichannels and P2 receptors - a putative mechanoreceptor complex involving the primary cilium?

(2009) M. M. Knight et al.   JOURNAL OF ANATOMY

The Na+/H+exchanger NHE1 is required for directional migration stimulated via PDGFR-α in the primary cilium

(2009) Linda Schneider et al.   JOURNAL OF CELL BIOLOGY

TheChlamydomonas reinhardtiiBBSome is an IFT cargo required for export of specific signaling proteins from flagella

(2009) Karl-Ferdinand Lechtreck et al.   JOURNAL OF CELL BIOLOGY

Growth arrest induces primary-cilium formation and sensitizes IGF-1-receptor signaling during differentiation induction of 3T3-L1 preadipocytes

(2009) D. Zhu et al.   JOURNAL OF CELL SCIENCE

p57KIP2: "Kip"ing the Cell under Control

(2009) I. S. Pateras et al.   MOLECULAR CANCER RESEARCH

The Insulin-Like Growth Factor (IGF) Receptor Type 1 (IGF1R) as an Essential Component of the Signalling Network Regulating Neurogenesis

(2009) Alexander Annenkov   MOLECULAR NEUROBIOLOGY

FGF signalling during embryo development regulates cilia length in diverse epithelia

(2009) Judith M. Neugebauer et al.   NATURE

INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse

(2009) Monique Jacoby et al.   NATURE GENETICS

Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies

(2009) Stephanie L Bielas et al.   NATURE GENETICS

Primary Cilia and Signaling Pathways in Mammalian Development, Health and Disease

(2009) Iben R. Veland et al.   NEPHRON PHYSIOLOGY

Common corruption of the mTOR signaling network in human tumors

(2009) S Menon et al.   ONCOGENE

FGF-dependent left-right asymmetry patterning in zebrafish is mediated by Ier2 and Fibp1

(2009) S.-K. Hong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell biology of embryonic migration

(2008) Satoshi Kurosaka et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Cell Cycle-Dependent Ciliogenesis and Cancer

(2008) O. V. Plotnikova et al.   CANCER RESEARCH

Intraflagellar transport and the sensory outer segment of vertebrate photoreceptors

(2008) Christine Insinna et al.   DEVELOPMENTAL DYNAMICS

Primary cilia in osteoarthritic chondrocytes: From chondrons to clusters

(2008) S.R. McGlashan et al.   DEVELOPMENTAL DYNAMICS

Assembly of primary cilia

(2008) Lotte B. Pedersen et al.   DEVELOPMENTAL DYNAMICS

Role of platelet-derived growth factors in physiology and medicine

(2008) J. Andrae et al.   GENES & DEVELOPMENT

Ultrastructural and antigenic properties of neural stem cells and their progeny in adult rat subventricular zone

(2008) Alexandre I. Danilov et al.   GLIA

Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery

(2008) Enko N. Kiprilov et al.   JOURNAL OF CELL BIOLOGY

Non-Random Distribution and Sensory Functions of Primary Cilia in Vascular Smooth Muscle Cells

(2008) C.J. Lu et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Evolution of the Insulin Receptor Family and Receptor Isoform Expression in Vertebrates

(2008) C. Hernandez-Sanchez et al.   MOLECULAR BIOLOGY AND EVOLUTION

Identification of Ciliary Localization Sequences within the Third Intracellular Loop of G Protein-coupled Receptors

(2008) Nicolas F. Berbari et al.   MOLECULAR BIOLOGY OF THE CELL

The solitary (primary) cilium–A mechanosensory toggle switch in bone and cartilage cells

(2007) J.F. Whitfield   CELLULAR SIGNALLING